scholarly journals Cerebral white matter volume changes in patients with obsessive-compulsive disorder: Voxel-based morphometry

2015 ◽  
Vol 69 (11) ◽  
pp. 717-723 ◽  
Author(s):  
Shin-Eui Park ◽  
Gwang-Woo Jeong
Keyword(s):  
White Matter ◽  
Obsessive Compulsive Disorder ◽  
Cerebral White Matter ◽  
Voxel Based Morphometry ◽  
White Matter Volume ◽  
Volume Changes ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Matter Volume

Changes in Gray Matter Volume and White Matter Microstructure in Adolescents with Obsessive-Compulsive Disorder

2011 ◽  
Vol 70 (11) ◽  
pp. 1083-1090 ◽  
Author(s):  
Mojtaba Zarei ◽  
David Mataix-Cols ◽  
Isobel Heyman ◽  
Morgan Hough ◽  
Joanne Doherty ◽  
...  
Keyword(s):  
White Matter ◽  
Obsessive Compulsive Disorder ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Matter Volume ◽  
White Matter Microstructure

The Structure of the OCD Brain

2017 ◽  
Author(s):  
Premika S. W. Boedhoe ◽  
Odile A. van den Heuvel
Keyword(s):  
White Matter ◽  
Diffusion Tensor ◽  
Future Research ◽  
Voxel Based Morphometry ◽  
White Matter Volume ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Subcortical Volumes ◽  
Diffusion Tensor Imaging Dti

This chapter summarizes the most consistent findings of structural neuroimaging studies of obsessive-compulsive disorder (OCD), and discusses their relationship within the implicated brain networks. The techniques used in these studies are diverse, and include manual tracing of specific regions of interest, whole-brain voxel-based morphometry (VBM) for both gray matter and white matter volume comparisons, FreeSurfer to investigate differences in cortical thickness and subcortical volumes, and other methods such as covariance analyses. Findings on white matter integrity with tract-based spatial statistics (TBSS) and in diffusion tensor imaging (DTI) studies are discussed as well.The literature shows that the pathophysiology of OCD cannot be explained by alterations in function and structure of the classical cortico-striato-thalamo-cortical (CSTC) regions exclusively, but that fronto-limbic and fronto-parietal connections are important as well, and the role of the cerebellum needs more attention in future research.

Sign in / Sign up

Export Citation Format

Share Document