Analgesic Effect of Light-Emitting Diode (LED) Therapy at Wavelengths of 635 and 945 nm onBothrops moojeniVenom-Induced Hyperalgesia

2013 ◽  
Vol 90 (1) ◽  
pp. 207-213 ◽  
Author(s):  
Nikele Nadur-Andrade ◽  
Stella R. Zamuner ◽  
Elaine F. Toniolo ◽  
Carlos J. de Lima ◽  
José C. Cogo ◽  
...  
2011 ◽  
Vol 65 (3) ◽  
pp. 224-229 ◽  
Author(s):  
Yasushi Oshima ◽  
Richard D. Coutts ◽  
Neil M. Badlani ◽  
Robert M. Healey ◽  
Toshikazu Kubo ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Yuan-Yi Chia ◽  
Chien-Cheng Liu ◽  
Guan-Ming Feng ◽  
Chia-Chih Alex Tseng ◽  
Kuo-Chuan Hung ◽  
...  

Background. Light-emitting diode (LED) phototherapy has been reported to relieve pain and enhance tissue repair through several mechanisms. However, the analgesic effect of LED on incised wounds has never been examined.Objectives. We examined the analgesic effect of LED therapy on incision pain and the changes in cyclooxygenase 2 (COX-2), prostaglandin E2 (PGE2), and the proinflammatory cytokines interleukin 6 (IL-6), IL-1β, and tumor necrosis factorα(TNF-α).Methods. Rats received LED therapy on incised skin 6 days before incision (L-I group) or 6 days after incision (I-L group) or from 3 days before incision to 3 days after incision (L-I-L group). Behavioral tests and analysis of skin tissue were performed after LED therapy.Results. LED therapy attenuated the decrease in thermal withdrawal latency in all the irradiated groups and the decrease in the mechanical withdrawal threshold in the L-I group only. The expression levels of COX-2, PGE2, and IL-6 were significantly decreased in the three LED-treated groups, whereas IL-1βand TNF-αwere significantly decreased only in the L-I group compared with their levels in the I groups (p<0.05).Conclusions. LED therapy provides an analgesic effect and modifies the expression of COX-2, PGE2, and proinflammatory cytokines in incised skin.


2005 ◽  
Author(s):  
Cheryl D. DiCarlo ◽  
Jeremiah Brown ◽  
Henry D. Hacker ◽  
Steven T. Schuschereba ◽  
Rachael D. Cheramie ◽  
...  

2008 ◽  
Vol 92 (5) ◽  
pp. 262-265 ◽  
Author(s):  
Shoukichi Kikugawa ◽  
Takahiro Morimitsu ◽  
Masaharu Yokoyama ◽  
Tomoki Kawamura ◽  
Shinichi Mitsumoto

2021 ◽  
Vol 50 (3) ◽  
pp. 301-306
Author(s):  
Xiaotong Xu ◽  
Ji-Eun Lee ◽  
So-Mi Jeong ◽  
Woo-Sin Kang ◽  
Si-Hyeong Ryu ◽  
...  

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