scholarly journals P1‐53: The combination of sarcoid lymphadenopathy and cystic formation of the mediastinum: Ways to optimize radiation diagnostics

Respirology ◽  
2021 ◽  
Vol 26 (S3) ◽  
pp. 94-94
Keyword(s):  
1995 ◽  
Vol 268 (5) ◽  
pp. F793-F801 ◽  
Author(s):  
F. Terzi ◽  
C. Ticozzi ◽  
M. Burtin ◽  
V. Motel ◽  
H. Beaufils ◽  
...  

It is generally accepted that renal compensatory growth after unilateral nephrectomy (Uni) is due to prominent hypertrophy with no involvement of protooncogenes. Neither the balance between hypertrophy and hyperplasia nor the expression of the early-growth-related genes has been studied after subtotal nephrectomy (Nx). The occurrence of cystic tubular dilatations after Nx may suggest an excessive cell proliferation in this model. We measured DNA, RNA, and protein content, number of nuclei per tubular section, as well as c-fos, c-jun, c-myc, c-H-ras, c-sis, and c-erb-B2 protooncogene expression in kidneys taken at time of surgery and 2, 7, and 14 days after sham operation (control rats), Uni, or Nx. After Uni, hyperplasia was greater than expected (+79% for DNA at day 14) and was associated with moderate hypertrophy (+11% for protein/DNA ratio). After Nx, compensatory growth was due only to hyperplasia (+117% for DNA at day 14), with unchanged protein/DNA ratio (vs. Uni, P < 0.02). The greater hyperplasia after Nx was confirmed by nuclei counting. The protooncogene mRNA expression was constantly absent in control and Uni rats, whereas that of c-fos and c-jun genes was detected in Nx rats at day 14 with a 2- to 12-fold increment. The c-fos and c-jun protein levels were also increased at that time in Nx rats. This suggests the following: 1) the cellular events following Uni and Nx are not the same, and 2) the late protooncogene expression in Nx exclusively could favor a particular type of cell proliferation possibly more related with cystic formation than with actual compensatory growth.


2018 ◽  
Vol 20 (suppl_6) ◽  
pp. vi58-vi58
Author(s):  
Ali Alattar ◽  
Brian Hirshman ◽  
Rushikesh Joshi ◽  
Clark Chen

2011 ◽  
Vol 64 (1-2) ◽  
pp. 89-92 ◽  
Author(s):  
Radovan Cvijanovic ◽  
Dejan Ivanov ◽  
Mirjana Zivojinov

Introduction. Teratomas are tumours derived from pluripotent germ cells. They appear most frequently on ovaries. However, other locations are also possible: testicles, retroperitoneum, stomach, neck, and bottom of the mouth cavity. It is not very common to find teratomas in two different body cavities. Case report. A 51-year-old patient visited her doctor complaining of an intensive pain which suddenly appeared in her low back. The computed tomography scan of the abdomen was performed, which revealed cystic formation, 12.5 x 18 cm in size, with remarkable capsule visualization. It had paraaortic, subdiaphragmatic, retropancreatic and suprarenal left localisation with signs of compression and pancreatic dislocation. The cystic formation had a septated appearance filled with clear fluid in all its parts except at the bottom, where it was dense. The intra-operative finding was left retroperitoneal mass placed above the left kidney, dislocating surrounding structures and their infiltration could not be excluded for sure. A tumour mass passed through the diaphragmatic hiatus and continued in the left thoracic space. The cyst was only drained and the fenestration was performed. Three months later, the second operation was performed-splenectomy, left suprarenaladenectomy, left nephrectomy, aortic deliberalisation, the left diaphragmatic crus was opened and tumour mass was completely removed from the thoracic space. The histological examination showed mature teratoma with morphological characterisations of the skin, so the definite diagnosis was dermoid cyst. Conclusion. The patient presented with thoracoabdominal teratoma. Although without malignant transformation, the teratoma required splenectomy, supraadrenalectomy and nefrectomy due to its position and size.


1974 ◽  
Vol 83 (17_suppl) ◽  
pp. 1-15 ◽  
Author(s):  
Allan L. Abramson ◽  
Robert L. Eason ◽  
William H. Pryor ◽  
Eugene J. Messer

Autogenous marrow-cancellous bone chips were transplanted into 36 canine frontal sinus cavities and studied over variable postoperative periods by radiographic and histologic methods. Cysts lined with frontal sinus mucosa were noted to enlarge progressively between three and 26 weeks. Cysts which originated from the ectoturbinate scroll frequently went on to communicate with the nasofrontal duct (neocavitation). If no cystic formation developed, this loosely packed autograft eventually was transformed into organized cancellous bone, thus obliterating the sinus cavity. When external frontal contour was evaluated, good results were obtained when the cavity was completely filled with cancellous autograft. If partial filling of the sinus cavity was performed, a variable amount of depression was noted.


2010 ◽  
Vol 4 (2) ◽  
pp. 102-103
Author(s):  
Koichi Sugimoto ◽  
Hiroyuki Koike ◽  
Kiyoshi Hashimoto ◽  
Atsunobu Esa

2020 ◽  
Vol 137 ◽  
pp. 235-238 ◽  
Author(s):  
Liang Wu ◽  
Ying Tian ◽  
Li'ao Wang ◽  
Dejiang Wang ◽  
Yulun Xu

1979 ◽  
Vol 88 (5) ◽  
pp. 701-707 ◽  
Author(s):  
J. H. T. Rambo

Variation in the quality of healing in mastoid cavities has never been clearly understood. It is the author's contention that the factor responsible for the wide variation in healing, even though all chronic disease has been removed, is buried mucosa which leads to cystic formation. Over the past 20 years the author has followed the principle of removing all mucosa from the mastoid segment and has been rewarded with dry ears routinely in open cavity surgery. For the past 12 years he has removed cholesteatoma through tympanoplasty and modified radical mastoidectomy. These cases, also, have been consistently free of cavity problems. In the late 50s and early 60s closed cavity operations were tried in radical mastoidectomy, fenestration and tympanoplasty with mastoidectomy. Postoperative healing difficulties were encountered then that are similar to those being reported now with intact canal wall operation. No conclusions are drawn in the controversy between open and closed cavity techniques. The observation may be made, nevertheless, that the problems of closed cavity operations have not been solved. It is the thesis of this paper that the main objection to open cavity operations, ie, poor quality of healing, has been resolved.


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