Lipopolysaccharide‐responsive beige‐like anchor acts as a cAMP‐dependent protein kinase anchoring protein in B cells

2020 ◽  
Vol 92 (3) ◽  
Author(s):  
Nidia Carolina Moreno‐Corona ◽  
Orestes Lopez‐Ortega ◽  
Jose Mizael Flores Hermenegildo ◽  
Laura Berron‐Ruiz ◽  
Juan Carlos Rodriguez‐Alba ◽  
...  
Keyword(s):  
B Cells ◽  
Protein Kinase ◽  
Dependent Protein Kinase ◽  
Camp Dependent Protein Kinase ◽  
Anchoring Protein ◽  
Dependent Protein

Sphingosine Kinase Interacting Protein is an A-Kinase Anchoring Protein Specific for Type I cAMP-Dependent Protein Kinase

ChemBioChem ◽  
2010 ◽  
Vol 11 (7) ◽  
pp. 963-971 ◽  
Author(s):  
Duangnapa Kovanich ◽  
Marcel A. G. van der Heyden ◽  
Thin Thin Aye ◽  
Toon A. B. van Veen ◽  
Albert J. R. Heck ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Sphingosine Kinase ◽  
Type I ◽  
Dependent Protein Kinase ◽  
Interacting Protein ◽  
Camp Dependent Protein Kinase ◽  
Anchoring Protein ◽  
Dependent Protein

scholarly journals PKA-phosphorylation of PDE4D3 facilitates recruitment of the mAKAP signalling complex

2004 ◽  
Vol 381 (3) ◽  
pp. 587-592 ◽  
Author(s):  
Jennifer J. CARLISLE MICHEL ◽  
Kimberly L. DODGE ◽  
Wei WONG ◽  
Nicole C. MAYER ◽  
Lorene K. LANGEBERG ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Negative Feedback ◽  
Feedback Loop ◽  
Negative Feedback Loop ◽  
Dependent Protein Kinase ◽  
Camp Dependent Protein Kinase ◽  
Anchoring Protein ◽  
Dependent Protein

mAKAP (muscle-selective A-kinase-anchoring protein) co-ordinates a cAMP-sensitive negative-feedback loop comprising PKA (cAMP-dependent protein kinase) and the cAMP-selective PDE4D3 (phosphodiesterase 4D3). In vitro and cellular experiments demonstrate that PKA-phosphorylation of PDE4D3 on Ser-13 increases the affinity of PDE4D3 for mAKAP. Our data suggest that activation of mAKAP-anchored PKA enhances the recruitment of PDE4D3, allowing for quicker signal termination.

Cover Picture: Sphingosine Kinase Interacting Protein is an A-Kinase Anchoring Protein Specific for Type I cAMP-Dependent Protein Kinase (ChemBioChem 7/2010)

ChemBioChem ◽  
2010 ◽  
Vol 11 (7) ◽  
pp. 833-833
Author(s):  
Duangnapa Kovanich ◽  
Marcel A. G. van der Heyden ◽  
Thin Thin Aye ◽  
Toon A. B. van Veen ◽  
Albert J. R. Heck ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Sphingosine Kinase ◽  
Type I ◽  
Dependent Protein Kinase ◽  
Interacting Protein ◽  
Camp Dependent Protein Kinase ◽  
Anchoring Protein ◽  
Dependent Protein
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