Genomic characterization of lumpy skin disease virus in southern China

2021 ◽  
Author(s):  
Jun Ma ◽  
Yaoxian Yuan ◽  
Jianwei Shao ◽  
Minghui Sun ◽  
Wei He ◽  
...  
Keyword(s):  
Disease Virus ◽  
Skin Disease ◽  
Southern China ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
Genomic Characterization

Molecular characterization of lumpy skin disease virus in Iran (2014–2018)

2021 ◽  
Author(s):  
Zeinab Hedayati ◽  
Hamid Reza Varshovi ◽  
Ali Mohammadi ◽  
Mohammad Tabatabaei
Keyword(s):  
Molecular Characterization ◽  
Disease Virus ◽  
Skin Disease ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus

scholarly journals Characterization of sheep pox virus vaccine for cattle against lumpy skin disease virus

2014 ◽  
Vol 109 ◽  
pp. 1-6 ◽  
Author(s):  
Eeva S.M. Tuppurainen ◽  
Caroline R. Pearson ◽  
Katarzyna Bachanek-Bankowska ◽  
Nick J. Knowles ◽  
Shadi Amareen ◽  
...  
Keyword(s):  
Disease Virus ◽  
Virus Vaccine ◽  
Skin Disease ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus

scholarly journals Genomic characterization of a lumpy skin disease virus isolated in southeast China

2021 ◽  
Author(s):  
Jun Ma ◽  
Yaoxian Yuan ◽  
Jianwei Shao ◽  
Minghui Sun ◽  
Weinan Huang ◽  
...  
Keyword(s):  
Disease Virus ◽  
Skin Disease ◽  
Vaccine Recombinant ◽  
Lumpy Skin Disease ◽  
Southeast China ◽  
Lumpy Skin Disease Virus ◽  
Mdbk Cells ◽  
Genomic Characterization ◽  
The One ◽  
And Control

SUMMARYLumpy skin disease virus (LSDV) is of high economic importance and has spread rapidly to many European and Asian countries in recent years. LSDVs spread to China in 2019 and have caused severe outbreaks in multiple provinces. The LSDVs in China have not been well investigated. Here we isolated an LSDV (GD01/2020) in southeast China and investigated its features in replication, phylogenetics, and genomics. GD01/2020 caused a typical LSD outbreak and replicated well in MDBK cells as detected by a novel quantitative real-time PCR assay targeting the viral GPCR gene. GD01/2020 was similar in phylogenetics to the one circulating in Xinjiang, China in 2019, and distinct from the LSDVs identified in other countries. In genomics, GD01/2020 was a vaccine-recombinant similar to those identified in Russia. A total of 13 major putative recombination events between a vaccine strain and a field strain were identified in the genome of GD01/2020, which could affect the virulence and transmissibility of the virus. The results suggested that the LSD outbreaks in China caused by a virulent vaccine-recombinant LSDV from the same unknown exotic source, and virulent vaccine-recombinant LSDVs obtained transboundary transmissibility. This report shed novel insights into the diagnosis, transmission, and control of the disease.

scholarly journals Molecular characterization of lumpy skin disease virus in Namibia, 2017

2018 ◽  
Vol 163 (9) ◽  
pp. 2525-2529
Author(s):  
Umberto Molini ◽  
Gottlieb Aikukutu ◽  
Siegfried Khaiseb ◽  
Naindji N. Haindongo ◽  
Angela C. Lilungwe ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Disease Virus ◽  
Skin Disease ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus

Full-length genome characterization of a novel recombinant vaccine-like lumpy skin disease virus strain detected during the climatic winter in Russia, 2019

2020 ◽  
Vol 165 (11) ◽  
pp. 2675-2677
Author(s):  
Alexander Sprygin ◽  
Antoinette Van Schalkwyk ◽  
Irina Shumilova ◽  
Alexander Nesterov ◽  
Svetlana Kononova ◽  
...  
Keyword(s):  
Disease Virus ◽  
Virus Strain ◽  
Skin Disease ◽  
Recombinant Vaccine ◽  
Full Length ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
Genome Characterization ◽  
Full Length Genome

scholarly journals Molecular characterization of lumpy skin disease virus (LSDV) emerged in Bangladesh reveals unique genetic features compared to contemporary field strains

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Shukes Chandra Badhy ◽  
Mohammad Golam Azam Chowdhury ◽  
Tirumala Bharani Kumar Settypalli ◽  
Giovanni Cattoli ◽  
Charles Euloge Lamien ◽  
...  
Keyword(s):  
Middle East ◽  
Molecular Characterization ◽  
Disease Virus ◽  
Skin Disease ◽  
Clinical Signs ◽  
Sequence Alignments ◽  
Multiple Sequence ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus

Abstract Background Lumpy skin disease (LSD) is a contagious viral disease of cattle caused by lumpy skin disease virus (LSDV). LSD has recently spread in Asia following outbreaks in the Middle East and Europe. The disease emerged in Bangladesh in July 2019 in the Chattogram district, then rapidly spread throughout the entire country. We investigated six LSD outbreaks in Bangladesh to record the clinical signs and collect samples for diagnostic confirmation. Furthermore, we performed the molecular characterization of Bangladesh isolates, analyzing the full RPO30 and GPCR genes and the partial EEV glycoprotein gene. Results Clinical observations revealed common LSD clinical signs in the affected cattle. PCR and real-time PCR, showed the presence of the LSDV genome in samples from all six districts. Phylogenetic analysis and detailed inspection of multiple sequence alignments revealed that Bangladesh isolates differ from common LSDV field isolates encountered in Africa, the Middle East, and Europe, as well as newly emerged LSDV variants in Russia and China. Instead, they were closely related to LSDV KSGP-0240, LSDV NI2490, and LSDV Kenya. Conclusions These results show the importance of continuous monitoring and characterization of circulating strains and the need to continually refine the strategies for differentiating vaccine strains from field viruses.

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