Early diagnosis of kidney transplant rejection and cyclosporin nephrotoxicity by urine cytology

1992 ◽  
Vol 5 ◽  
pp. S13-S16 ◽  
Author(s):  
M. Kyo ◽  
F. Gudat ◽  
P. Dalquen ◽  
B. Huser ◽  
G. Thiel ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Kidney Transplant ◽  
Transplant Rejection ◽  
Urine Cytology

Differential diagnosis of kidney transplant rejection and cyclosporin/tacrolimus nephropathy using urine cytology

2002 ◽  
Vol 16 ◽  
pp. 40-44 ◽  
Author(s):  
Masahiro Kyo ◽  
Yasuji Ichikawa ◽  
Kiyohide Toki ◽  
Kennichi Nishimura ◽  
Takanobu Fukunishi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Kidney Transplant ◽  
Transplant Rejection ◽  
Urine Cytology

Monitoring Of Human Kidney Transplants Using Quantification Of Autologous 111Indium -Oxine Platelet Label Deposition - Beneficial Effect Of PGI2-Treatment In Acute (AR) And Chronic Rejection (CR)

1981 ◽  
Author(s):  
H Sinzinger ◽  
Ch Leithner ◽  
M Schwarz
Keyword(s):  
Early Diagnosis ◽  
Acute Rejection ◽  
Serum Creatinine ◽  
Beneficial Effect ◽  
Transplant Rejection ◽  
Human Kidney ◽  
Controlled Study ◽  
Platelet Deposition ◽  
Transplant Function ◽  
Diagnosis Of Rejection

Eighty patients with AR and chronic transplant rejection as well as with a stable transplant function were monitored by a combination of quantification of 111In-oxine labeled platelet uptake in the transplanted kidney (under γ- camera) and platelet survival (PS). In acute phase after transplantation the patients were controlled twice or three times a day until 3-4 weeks (weekly platelet labeling) after the transplantation. The quantification of platelet deposition (index (i): transplant region:contralateral region/cts. per 5 minutes) is demonstrated to be a very useful parameter of early diagnosis of rejection crisis. In AR i reaches values up to 2,00, the PS between 24 and 72 hours. In constant transplant function i below 1,20 are found, indicating that also in patients without any clinical sign of rejection, a platelet deposition and a shortening of PS occurs. In 8 patients with CR (i: 1,201,35; PS: 60-96 hours) and one week continuous i.v. PG2-administration (5ng PG2/kg/min) leads to a decrease in platelet deposition (i: minus 0,10-0,15) and a prolongation of PS. In 4 of these patients also the serum creatinine was decreased between 0,5 and 1,1 mg%. Using thereafter a combination of antiplatelet drugs we try now to retain the platelet deposition at the lower level reached by means of the PGI2application. Similar beneficial data could be obtained by treating acute rejection with PGI2-infusion. The preliminary data of a controlled study and the platelet function behaviour during PGI2 are reported.

scholarly journals Anti‐interleukin‐6 antibody clazakizumab in late antibody‐mediated kidney transplant rejection: effect on cytochrome P450 drug metabolism

2021 ◽  
Author(s):  
Jakob Mühlbacher ◽  
Christian Schörgenhofer ◽  
Konstantin Doberer ◽  
Michael Dürr ◽  
Klemens Budde ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Kidney Transplant ◽  
Interleukin 6 ◽  
Transplant Rejection

INDIUM-111 LABELLED PLATELETS IN CHRONIC KIDNEY TRANSPLANT REJECTION

The Lancet ◽  
1980 ◽  
Vol 316 (8187) ◽  
pp. 213-214 ◽  
Author(s):  
CH. Leithner ◽  
H. Sinzinger ◽  
P. Angelberger ◽  
G. Syre
Keyword(s):  
Kidney Transplant ◽  
Transplant Rejection ◽  
Indium 111

Kidney injury molecule-1 and osteopontin: New markers for prediction of early kidney transplant rejection

2013 ◽  
Vol 54 (3-4) ◽  
pp. 457-464 ◽  
Author(s):  
Zhan-Kui Jin ◽  
Pu-Xun Tian ◽  
Xu-Zhen Wang ◽  
Wu-Jun Xue ◽  
Xiao-Ming Ding ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Transplant Rejection ◽  
Kidney Injury ◽  
Kidney Injury Molecule 1
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