scholarly journals An examination of certain factors which might, or do, affect the vascular response to oxytocin

1967 ◽  
Vol 193 (3) ◽  
pp. 547-569 ◽  
Author(s):  
Sybil Lloyd ◽  
Mary Pickford
Keyword(s):  
Vascular Response

scholarly journals Influence of group B streptococci on piglet pulmonary artery response to bradykinin

1999 ◽  
Vol 86 (1) ◽  
pp. 61-65 ◽  
Author(s):  
Richard M. Whitehurst ◽  
Rachel Laskey ◽  
Ronald N. Goldberg ◽  
Donald Herbert ◽  
Cornelius Van Breemen
Keyword(s):  
Pulmonary Artery ◽  
Contractile Response ◽  
Isometric Force ◽  
Control Group ◽  
Relaxed Controls ◽  
Vascular Response ◽  
Group B Streptococci ◽  
Resting Tension ◽  
Neonatal Group ◽  
Group B

To study whether a sepsis-induced increase in des-Arg9-bradykinin (des-Arg9-BK) and bradykinin (BK) B1-receptor activity participates in the observed increase in pulmonary vascular resistance in neonatal group B streptococcal sepsis (GBS), isometric force bioassays of pulmonary artery (PA) rings were studied, after 4-h exposure to either Krebs or GBS, by using the following protocols: 1) BK dose-response curve, 2) vascular response to BK with N G-nitro-l-arginine methyl ester (l-NAME), and 3) response to des-Arg9-BK (BK metabolite and B1 agonist). PA rings exposed to BK resulted in contraction in the GBS group and a decrease in resting tension in the Control group ( P = 0.034) at a concentration of 10−5 M. GBS-treated PA rings contracted more to des-Arg9-BK than did Controls ( P < 0.001). BK (10−6 M) relaxed preconstricted PA rings incubated in GBS less than BK relaxed Controls ( P < 0.001), and preincubation withl-NAME decreased relaxation in both. These results suggest that GBS decreased endothelium-dependent BK relaxation and increased contractile response to des-Arg9-BK. We speculate that this occurs secondary to upregulation of B1 receptors reflected by B1-agonist-mediated PA contraction.

Involvement of proteinase activated receptor-2in the vascular response to sphingosine 1-phosphate

2013 ◽  
Vol 126 (8) ◽  
pp. 545-556 ◽  
Author(s):  
Fiorentina Roviezzo ◽  
Antonella De Angelis ◽  
Luana De Gruttola ◽  
Antonio Bertolino ◽  
Nikol Sullo ◽  
...  
Keyword(s):  
Vascular Inflammation ◽  
Vascular Response ◽  
Vascular Effect ◽  
Vascular Responses ◽  
Sphingosine 1 Phosphate

S1P exerts a diverse set of vascular responses, and PAR-2 has been shown to be involved in vascular inflammation as well as in other inflammatory-based diseases. In the present study, we demonstrate that S1P-mediated vascular effect involves PAR-2 activation.

A Novel α-Conotoxin Identified by Gene Sequencing Is Active in Suppressing the Vascular Response to Selective Stimulation of Sensory Nerves in Vivo†

Biochemistry ◽  
2003 ◽  
Vol 42 (22) ◽  
pp. 6904-6911 ◽  
Author(s):  
D. W. Sandall ◽  
N. Satkunanathan ◽  
D. A. Keays ◽  
M. A. Polidano ◽  
X. Liping ◽  
...  
Keyword(s):  
Gene Sequencing ◽  
Sensory Nerves ◽  
Vascular Response ◽  
Selective Stimulation ◽  
Stimulation Of

Trait anxiety and peripheral vascular response to mental stress — Sex differences

2008 ◽  
Vol 69 (3) ◽  
pp. 268
Author(s):  
M. Marinov ◽  
Z. Stoyanov ◽  
I. Boncheva ◽  
I. Vartanyan ◽  
T. Chernigovskaya
Keyword(s):  
Sex Differences ◽  
Trait Anxiety ◽  
Mental Stress ◽  
Vascular Response ◽  
Peripheral Vascular
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