scholarly journals Respiratory modulation of muscle sympathetic nerve activity is not increased in essential hypertension or chronic obstructive pulmonary disease

2011 ◽  
Vol 589 (20) ◽  
pp. 4997-5006 ◽  
Author(s):  
Rania Fatouleh ◽  
Vaughan G. Macefield
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Essential Hypertension ◽  
Pulmonary Disease ◽  
Sympathetic Nerve ◽  
Sympathetic Nerve Activity ◽  
Muscle Sympathetic Nerve Activity ◽  
Chronic Obstructive ◽  
Nerve Activity ◽  
Obstructive Pulmonary Disease ◽  
Respiratory Modulation

Impact of Non-Invasive Ventilation on Sympathetic Nerve Activity in Chronic Obstructive Pulmonary Disease

Lung ◽  
2016 ◽  
Vol 195 (1) ◽  
pp. 69-75 ◽  
Author(s):  
Helge Haarmann ◽  
Jan Folle ◽  
Xuan Phuc Nguyen ◽  
Peter Herrmann ◽  
Karsten Heusser ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Sympathetic Nerve ◽  
Sympathetic Nerve Activity ◽  
Chronic Obstructive ◽  
Invasive Ventilation ◽  
Nerve Activity ◽  
Obstructive Pulmonary Disease ◽  
Non Invasive ◽  
Non Invasive Ventilation

scholarly journals PECULIARITIES OF APOPTOTIC MARKER EXPRESSION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ARTERIAL HYPERTENSION

2018 ◽  
Vol 18 (4) ◽  
pp. 65-71
Author(s):  
O.S. Tyaglaya
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Essential Hypertension ◽  
Arterial Hypertension ◽  
Pulmonary Disease ◽  
Cysteine Proteases ◽  
Chronic Obstructive ◽  
Significant Elevation ◽  
Caspase 9 ◽  
Obstructive Pulmonary Disease ◽  
Caspase 7

It is known that both chronic obstructive pulmonary disease and arterial hypertension are multifactorial diseases, and develop as a result of a complex interaction of genetic and environmental factors. The purpose of this work was to study the metabolism of caspase-7 and caspase-9 in patients with chronic obstructive pulmonary disease (COPD) in combination with arterial hypertension (AH). Materials and methods. We examined 23 patients with a diagnosis of essential hypertension stage II and COPD stage II without a clinically significant concomitant pathology. The plasma level of caspase-7 and caspase-9 was determined using the appropriate ELISA test systems (manufacturer – Bender Medsystems, Austria) at the Medical and Laboratory Training Centre of Zaporizhzhia State Medical University in accordance with the instructions attached to the kit. The analysis of the dynamics of the studied cysteine ​​proteases indicates a statistically significant elevation of these apoptosis markers in the conditions of hypertension and COPD. The value of caspase-7 in the cohort of patients with COPD + AH significantly exceeded similar figures for the groups of patients with a single pathology presented by AH or COPD, and averaged 0.41 ± 0.09 ng / ml. A statistically significant elevation of the caspase-9 level in patients with COPD + AH up to 2.16 ± 0.29 ng / ml compared with other groups also indicates a more significant induction of apoptotic processes in comorbid pathology than in isolated AH or COPD. Conclusion. The obtained results require further clarification of the nature of the relationship between changes in the metabolism of cysteine ​​proteases and the primacy of pathogenetic processes in the mechanisms of risk formation for complications and progression of ventilation disorders in patients with COPD and comorbid essential hypertension.

scholarly journals Effect of respiratory rehabilitation techniques on the autonomic function in patients with chronic obstructive pulmonary disease: A systematic review

2016 ◽  
Vol 14 (3) ◽  
pp. 217-230 ◽  
Author(s):  
Jibril Mohammed ◽  
Hellen Da Silva ◽  
Jessica Van Oosterwijck ◽  
Patrick Calders
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Autonomic Function ◽  
Evidence Synthesis ◽  
Muscle Sympathetic Nerve Activity ◽  
Chronic Obstructive ◽  
Oxygen Supplementation ◽  
Obstructive Pulmonary Disease ◽  
Breathing Techniques ◽  
Controlled Breathing

Patients with chronic obstructive pulmonary disease (COPD) show several extrapulmonary abnormalities such as impairment in the autonomic function (AF). Similarly, the use of respiratory training techniques such as controlled breathing techniques, noninvasive mechanical ventilation (NIMV), and oxygen supplementation for AF modulation in patients with COPD is popular in existing literature. However, the evidence to support their use is nonexistent. A systematic search of studies reporting on the effect of controlled breathing techniques, NIMV, and/or oxygen supplementation techniques on AF outcome parameters was conducted in three online databases: PubMed, Embase, and Web of Science. Following the Preferred Reporting Items for Systematic reviews and Meta-Analyses statement, relevant studies were retained and qualitatively analyzed for evidence synthesis. The methodological quality in these studies was evaluated using the evidence based guideline development (EBRO) checklists per designs provided by the Dutch Cochrane Centre. Eighteen studies met the inclusion criteria of the review and were included and discussed. The evidence synthesis revealed that a strong and moderate level evidence supported oxygen supplementation and slow breathing techniques, respectively, in significantly enhancing the baroreceptor sensitivity (BRS) values in patients with COPD. The effect of the examined techniques on the heart rate variability and muscle sympathetic nerve activity was of a limited or inconsistent evidence. The findings from this review suggest that oxygen supplementation and controlled breathing techniques have profound positive influence on the BRS in patients with COPD. However, it is not fully clear whether these influence translates to any therapeutic benefit on the general AF of patients with COPD in the long term.

scholarly journals Respiratory modulation of muscle sympathetic nerve activity in obstructive sleep apnoea

2014 ◽  
Vol 99 (10) ◽  
pp. 1288-1298 ◽  
Author(s):  
Rania Fatouleh ◽  
David K. McKenzie ◽  
Vaughan G. Macefield
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Sympathetic Nerve ◽  
Sympathetic Nerve Activity ◽  
Muscle Sympathetic Nerve Activity ◽  
Sleep Apnoea ◽  
Nerve Activity ◽  
Obstructive Sleep ◽  
Respiratory Modulation

CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) IS ASSOCIATED WITH SYMPATHETIC NERVE HYPERACTIVITY

2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S68-S69
Author(s):  
Y. B. Svernsdóttir ◽  
C. Ashley ◽  
V. G. Macefield
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Sympathetic Nerve ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

Impaired baroreflex changes in muscle sympathetic nerve activity in adolescents who have a family history of essential hypertension

1988 ◽  
Vol 6 (4) ◽  
pp. S525-528 ◽  
Author(s):  
Yutaka Yamada ◽  
Eiji Miyajima ◽  
Osamu Tochikubo ◽  
Toshiyoshi Matsukawa ◽  
Hiroshi Shionoiri ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Family History ◽  
Sympathetic Nerve ◽  
Sympathetic Nerve Activity ◽  
Muscle Sympathetic Nerve Activity ◽  
Nerve Activity ◽  
History Of
Sign in / Sign up

Export Citation Format

Share Document