scholarly journals Validation of a CFD Methodology for Positive Displacement LVAD Analysis Using PIV Data

2009 ◽  
Vol 131 (11) ◽  
Author(s):  
Richard B. Medvitz ◽  
Varun Reddy ◽  
Steve Deutsch ◽  
Keefe B. Manning ◽  
Eric G. Paterson
Keyword(s):  
Left Ventricular ◽  
Hydrodynamic Performance ◽  
Ventricular Assist ◽  
Shear Rates ◽  
Eddy Simulation ◽  
Positive Displacement ◽  
Image Velocimetry ◽  
Computational Fluid Dynamics Cfd ◽  
High Level

Computational fluid dynamics (CFD) is used to asses the hydrodynamic performance of a positive displacement left ventricular assist device. The computational model uses implicit large eddy simulation direct resolution of the chamber compression and modeled valve closure to reproduce the in vitro results. The computations are validated through comparisons with experimental particle image velocimetry (PIV) data. Qualitative comparisons of flow patterns, velocity fields, and wall-shear rates demonstrate a high level of agreement between the computations and experiments. Quantitatively, the PIV and CFD show similar probed velocity histories, closely matching jet velocities and comparable wall-strain rates. Overall, it has been shown that CFD can provide detailed flow field and wall-strain rate data, which is important in evaluating blood pump performance.

HYDRAULICS AND IN VITRO HEMOLYSIS TEST OF A MAGLEV IMPLANTABLE VENTRICULAR ASSIST DEVICE

2017 ◽  
Vol 17 (07) ◽  
pp. 1740023
Author(s):  
GUANGHUI WU ◽  
CHUANGYE XU ◽  
XIUJIAN LIU ◽  
CHANGYAN LIN ◽  
LIN YANG ◽  
...  
Keyword(s):  
Left Ventricular Assist Device ◽  
Ventricular Assist Device ◽  
Left Ventricular ◽  
Hydrodynamic Performance ◽  
In Vitro Tests ◽  
Animal Testing ◽  
Assist Device ◽  
Ventricular Assist ◽  
Left Ventricular Assist

A small implantable centrifugal left ventricular assist device, the CH-VAD (CH Biomedical Inc, JiangSu, China), featuring a magnetically levitated impeller is under development. The goal of this study is to validate hydrodynamic performance and hemocompatibility of the pump through in vitro studies. The hydraulic performance was quantified experimentally by using in vitro circulation loop system, and it turned out that the pump could deliver 5[Formula: see text]L/min under a pressure of 100[Formula: see text]mmHg at a rotational speed of approximate 3400[Formula: see text]rpm. A series of in vitro tests were established according to ASTM F1841, the standard practice for the assessment of hemolysis in continuous-flow blood pumps. The results showed that the average normalized index of hemolysis (NIH) value of the VAD was 0.0007[Formula: see text][Formula: see text][Formula: see text]0.0003[Formula: see text]mg/dL. The magnetic levitation left ventricular assist device (LVAD) has good hemolytic performance and stable mechanical property. These acceptable performance results supported proceeding initial acute animal testing conditions.

A Systemic Mock Circulation for In-Vitro Testing of a Pneumatically Operated Left Ventricular Assist Device

2014 ◽  
Vol 47 (3) ◽  
pp. 8409-8414 ◽  
Author(s):  
A. Karabegovic ◽  
M. Hinteregger ◽  
C. Janeczek ◽  
W. Reichenfelser ◽  
V. Soragnese ◽  
...  
Keyword(s):  
Left Ventricular Assist Device ◽  
Ventricular Assist Device ◽  
Left Ventricular ◽  
In Vitro Testing ◽  
Assist Device ◽  
Ventricular Assist ◽  
Mock Circulation ◽  
Left Ventricular Assist

Defibrillator-Heart Pump: An Implantable Ventricular Assist Device With Integrated Defibrillator Component—The First In Vitro Testing

2019 ◽  
Vol 26 (6) ◽  
pp. 720-724
Author(s):  
Anas Aboud ◽  
Kai Liebing ◽  
Charlie Abraham ◽  
Jan-Christian Reil ◽  
Yara Turkistani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Therapeutic Option ◽  
Left Ventricular ◽  
Ventricular Assist Devices ◽  
In Vitro Testing ◽  
Left Ventricular Assist Devices ◽  
Ventricular Assist ◽  
Heart Pump ◽  
Increased Risk

Left ventricular assist devices (LVADs) are an important therapeutic option for patients with end-stage heart failure waiting for heart transplantation or in older patients as definite therapy for heart failure. Interestingly, about 62% of patients receiving LVADs do not have an automatic implantable cardioverter-defibrillator (AICD) at the time of implantation, although these patients have increased risk of being confronted with dangerous arrhythmia. Therefore, an LVAD system including AICD function is a reasonable alternative for such heart failure patients thereby avoiding a second surgical intervention for AICD implantation. In this article, a newly developed system including LVAD and AICD function is introduced, and we also report its first in vitro testing.

In vitro performance of trans‐valve left ventricular assist device installed at aortic valve position

2020 ◽  
Vol 44 (10) ◽  
pp. 1067-1072
Author(s):  
Eiji Okamoto ◽  
Tetsuya Yano ◽  
Yusuke Inoue ◽  
Yasuyuki Shiraishi ◽  
Tomoyuki Yambe ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Left Ventricular Assist Device ◽  
Ventricular Assist Device ◽  
Left Ventricular ◽  
Assist Device ◽  
Ventricular Assist ◽  
Left Ventricular Assist ◽  
Valve Position ◽  
In Vitro Performance

Reliability Model from the In Vitro Durability Tests of a Left Ventricular Assist System

ASAIO Journal ◽  
1999 ◽  
Vol 45 (6) ◽  
pp. 595-601 ◽  
Author(s):  
JAMES LEE ◽  
PHILLIP J. MILLER ◽  
HERB CHEN ◽  
MICHAEL C. CONLEY ◽  
JAMES L. CARPENTER ◽  
...  
Keyword(s):  
Left Ventricular ◽  
Reliability Model ◽  
Left Ventricular Assist System ◽  
Ventricular Assist ◽  
Left Ventricular Assist
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