High Pressure On-Chip Valves for Thermoplastic Microfluidics
Keyword(s):
A high-pressure microvalve technology based on the integration of discrete elastomeric elements into rigid thermoplastic chips is described. The low-dead-volume valves employ deformable polydimethylsiloxane (PDMS) plugs actuated using a threaded stainless steel needle, allowing exceptionally high pressure resistance to be achieved. The simple fabrication process is made possible through the use of poly(ethylene glycol) (PEG) as a removable blocking material to avoid contamination of PDMS within the flow channel while yielding a smooth contact surface with the PDMS valve surface. Burst pressure tests reveal that the valves can withstand over 24MPa without leakage.
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1999 ◽
Vol 1
(23)
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pp. 5369-5375
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Keyword(s):
2009 ◽
Vol 286
(2)
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pp. 162-169
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Keyword(s):
Keyword(s):
2017 ◽
Vol 62
(6)
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pp. 1853-1858
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