Pulsatile Pressure System for Cellular Mechanical Stimulation

Author(s):  
Rebecca Taylor ◽  
Oscar Abilez ◽  
Feng Cao ◽  
Joe Wu ◽  
Chengpei Xu ◽  
...  

Cardiovascular disease (CVD) affects more than 71 million Americans accounting annually for nearly $400 billion in US health care costs. [1] In adult tissues such as the heart, the capacity for self-regeneration is limited. Recently, stem cell therapy has emerged as a promising methodology for myocardial repair.

Heart ◽  
2005 ◽  
Vol 91 (5) ◽  
pp. 696-702 ◽  
Author(s):  
P. L Weissberg

2016 ◽  
Vol 38 (1) ◽  
pp. 23-29 ◽  
Author(s):  
RONGRONG SUN ◽  
XIANCHI LI ◽  
MIN LIU ◽  
YI ZENG ◽  
SHUANG CHEN ◽  
...  

2006 ◽  
Vol 3 (S1) ◽  
pp. S138-S151 ◽  
Author(s):  
Pedro L Sánchez ◽  
José Alberto San Román ◽  
Adolfo Villa ◽  
María Eugenia Fernández ◽  
Francisco Fernández-Avilés

2010 ◽  
Vol 19 (7) ◽  
pp. 1109-1120 ◽  
Author(s):  
Premal Trivedi ◽  
Nancy Tray ◽  
Thuy Nguyen ◽  
Neha Nigam ◽  
G. Ian Gallicano

2008 ◽  
Vol 207 (3) ◽  
pp. 423-434 ◽  
Author(s):  
Nathan M. Novotny ◽  
Rinki Ray ◽  
Troy A. Markel ◽  
Paul R. Crisostomo ◽  
Meijing Wang ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Yang-Ying Liao ◽  
Zhi-Yi Chen ◽  
Yi-Xiang Wang ◽  
Yan Lin ◽  
Feng Yang ◽  
...  

Angiogenesis plays a vital part in the pathogenesis and treatment of cardiovascular disease and has become one of the hotspots that are being discussed in the past decades. At present, the promising angiogenesis therapies are gene therapy and stem cell therapy. Besides, a series of studies have shown that the ultrasound targeted microbubble destruction (UTMD) was a novel gene delivery system, due to its advantages of noninvasiveness, low immunogenicity and toxicity, repeatability and temporal and spatial target specificity; UTMD has also been used for angiogenesis therapy of cardiovascular disease. In this review, we mainly discuss the combination of UTMD and gene therapy or stem cell therapy which is applied in angiogenesis therapy in recent researches, and outline the future challenges and good prospects of these approaches.


VASA ◽  
2016 ◽  
Vol 45 (3) ◽  
pp. 260-260
Author(s):  
Holger Reinecke ◽  
Hendrik Reinecke ◽  
Harald Reinecke ◽  
Hans Reinecke

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