Determining the Mechanical Properties of Coronary Sinus for Percutaneous Mitral Valve Repair

2008 ◽  
Author(s):  
Thuy M. Pham ◽  
Xuan H. Nguyen ◽  
Milton DeHerrera ◽  
Wei Sun
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Operative Mortality ◽  
Treatment Options ◽  
Mitral Valve Regurgitation ◽  
Current Treatment ◽  
Valve Repair ◽  
Percutaneous Mitral Valve Repair ◽  
Surgical Treatments

Mitral valve regurgitation, the leakage of blood back to the left atrium during systole, is a significant cause of morbidity and mortality. The current treatment options for symptomatic mitral regurgitation are mitral valve replacement and mitral valve repair. However, the operative mortality for both of these treatments remains substantial[1]. Furthermore, these treatments are often not referred for elderly patients with comorbidities. Thus, there is a pressing need for less invasive, non-surgical treatments of mitral regurgitation.

Biomechanical Properties of Human Coronary Sinus for Minimally Invasive Mitral Valve Repair

2010 ◽  
Author(s):  
Thuy Pham ◽  
Wei Sun
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Operative Mortality ◽  
Treatment Options ◽  
Mitral Valve Regurgitation ◽  
Biomechanical Properties ◽  
Current Treatment ◽  
Valve Repair ◽  
Surgical Treatments

Mitral valve regurgitation, the leakage of blood back to the left atrium during systole, is a significant cause of morbidity and mortality. The current treatment options for symptomatic mitral regurgitation are mitral valve repair and replacement. However, the operative mortality for both of these treatments remains substantial (1). Furthermore, these treatments are often not referred for elderly patients with comorbidities. Thus, there is a pressing need for less invasive, non-surgical treatments of mitral regurgitation.

scholarly journals Percutaneous Mitral Valve Repair with the MitraClip System in the Current Clinical Practice

Hearts ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 74-86
Author(s):  
Sergio Sorrentino ◽  
Alessandra Berardini ◽  
Giovanni Statuto ◽  
Andrea Angeletti ◽  
Giulia Massaro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Randomized Clinical Trials ◽  
Treatment Options ◽  
Mitral Valve Regurgitation ◽  
Valve Repair ◽  
Percutaneous Mitral Valve Repair ◽  
Mitraclip System

Severe mitral valve regurgitation (MR) carries a significant burden both in prognosis and quality of life of patients, as well as on healthcare systems, with high rates of hospitalization for heart failure. While mitral valve surgery constitutes the first-line treatment option for primary MR in suitable patients, surgical treatment for secondary severe MR remains controversial, with a substantial lack of evidence on a survival benefit. In recent decades, percutaneous mitral valve repair has emerged as an alternative treatment for patients deemed not suitable for surgery. Among several devices under development or evaluation, the MitraClip system is the most widespread and is supported by the strongest evidence. While the role of MitraClip in patients with chronic primary MR who are not deemed suitable for surgery is well established, with consistent data showing improvement in both prognosis and quality of life, MitraClip treatment in secondary MR is a rapidly evolving field. Two recent randomized clinical trials generated apparently controversial results but actually provided an interesting pathophysiologic frame that could help discerning patients who will benefit from the procedure versus patients who will not. In this review, we will discuss current treatment options for mitral regurgitation, focusing on percutaneous mitral valve repair with the MitraClip system.

Percutaneous Mitral Valve Repair Vs. Stand-Alone Medical Therapy in Patients with Functional Mitral Regurgitation and Heart Failure

2020 ◽  
Vol 21 (1) ◽  
pp. 52-60 ◽  
Author(s):  
Tomás Benito-González ◽  
Rodrigo Estévez-Loureiro ◽  
Pedro A. Villablanca ◽  
Patrizio Armeni ◽  
Ignacio Iglesias-Gárriz ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Medical Therapy ◽  
Functional Mitral Regurgitation ◽  
Valve Repair ◽  
Percutaneous Mitral Valve Repair

Early and Mid-term Results of Mitral Valve Repair in Patients with Degenerative Mitral Regurgitation

2021 ◽  
Author(s):  
Hasan Erdem ◽  
Emre Selçuk
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Survival Rates ◽  
Mitral Valve Regurgitation ◽  
Valve Repair ◽  
Repair Rate ◽  
Mitral Repair ◽  
Mid Term Results

Objectives: In this study, we present the mid-term results of patients who underwent valve repair due to degenerative mitral valve regurgitation in the first five years of our mitral valve repair program. Patients and Methods: In this retrospective study, all patients who were operated for degenerative mitral regurgitation by a single surgical team between 2013 and 2017 were investigated. We determined early and mid-term cumulative survival rates, repair failure and freedom from reoperation. In addition, as a specific subgroup, the results of patients under 18 years of age after mitral valve repair were investigated Results: Mitral repair was performed in 121 of 153 degenerative mitral regurgitation patients during the study period. The overall repair rate was 79%. Mitral valve repair rate increased significantly over years. The Median follow-up time was 63 (range 10-92) months. Early mortality was 2.5% (n=3 patients). During the follow-up period, moderate-to-severe mitral regurgitation was observed in 14 (11.8%) patients, mitral valve reoperation was required in 7 (5.9%) patients. Valve repair was performed in 4 of 7 patients under the age of 18. There was no pediatric case requiring reoperation during the follow-up period (median 46 months). Conclusion: Mid-term results of mitral valve repair in degenerative mitral valve patients are satisfactory. The success rate of repair increases in line with surgical experience.

Percutaneous Mitral Valve Repair With Mitraclip® System in a Patient With Acute Mitral Regurgitation After Myocardial Infarction

2015 ◽  
Vol 68 (3) ◽  
pp. 259-261
Author(s):  
Miguel Rodríguez-Santamarta ◽  
Rodrigo Estévez-Loureiro ◽  
Javier Gualis ◽  
David Alonso ◽  
Armando Pérez de Prado ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Valve Repair ◽  
Percutaneous Mitral Valve Repair ◽  
Acute Mitral Regurgitation
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