A New Generation of Aortic Valve Prosthesis: Design, Manufacture and Hydrodynamic Assessment

2012 ◽  
Author(s):  
Benyamin Rahmani ◽  
Hossein Ghanbari ◽  
Spyridon Tzamtzis ◽  
Gaetano Burriesci ◽  
Alexander M. Seifalian
Keyword(s):  
Aortic Valve ◽  
Heart Valves ◽  
Artery Bypass ◽  
Polymeric Materials ◽  
Valve Prosthesis ◽  
Nanocomposite Polymer ◽  
Cardiac Procedure ◽  
Aortic Valve Prosthesis ◽  
Suboptimal Design ◽  
New Generation

Aortic valve replacement (AVR) is the second most common cardiac procedure after coronary artery bypass grafting, accounting for more than 200,000 transplantations annually worldwide [1]. Currently available mechanical and bioprosthetic heart valve replacements are not ideal as they are associated with relevant complications. The tri-leaflet polymeric heart valves (PHVs) have been widely investigated as possible alternative to these substitutes. However, the clinical application of PHVs has been limited by their suboptimal design and poor durability of available polymeric materials. This study presents a new concept of surgical aortic valve using a novel nanocomposite polymer.

Proposed percutaneous aortic valve prosthesis made of cryogel

2019 ◽  
Vol 233 (5) ◽  
pp. 515-524 ◽  
Author(s):  
Hadi Mohammadi ◽  
Dylan Goode ◽  
Guy Fradet ◽  
Kibret Mequanint
Keyword(s):  
Aortic Valve ◽  
Heart Valves ◽  
Kidney Injury ◽  
Blood Stream ◽  
Valve Prosthesis ◽  
Element Analysis ◽  
Novel Approach ◽  
Natural Geometry ◽  
Myocardial Infraction ◽  
Aortic Valve Prosthesis

Transcatheter heart valves are promising for high-risk patients. Generally, their leaflets are made of pericardium stented in a Nitinol basket. Despite their relative success, they are associated with significant complications such as valve migration, implantation risks, stroke, coronary obstruction, myocardial infraction, acute kidney injury (which all are due to the release of detached solid calcific pieces in to the blood stream) and expected issues existing with tissue valves such as leaflet calcification. This study is an attempt to fabricate the first ever polymeric percutaneous valves made of cryogel following the geometry and mechanical properties of porcine aortic valve to address some of the above-mentioned shortcomings. A novel, one-piece, tricuspid percutaneous valve, consisting of leaflets made entirely from the hydrogel, polyvinyl alcohol cryogel reinforced by bacterial cellulose natural nanocomposite, attached to a Nitinol basket was developed and demonstrated. Following the natural geometry of the valve, a novel approach was applied based on the revolution about an axis of a hyperboloid shape. The geometry was modified based on avoiding sharp warpage of leaflets and removal of the central opening orifice area of the valve when valve is fully closed using the finite element analysis. The modified geometry was replaced by a cloud of (control) points and was essentially converted to Bezier surfaces for further adjustment. A cavity mold was then designed and fabricated to form the valve. The fabricated valve was sewn into the Nitinol basket which is covered by Dacron cloth. The models presented in this study merit further development and revisions for both aortic and mitral positions.

scholarly journals 49 years of normal functioning Starr–Edwards aortic valve prosthesis

2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Mouhamed Amr Sabouni ◽  
Robin H Baumeister ◽  
Paul Traverse
Keyword(s):  
Aortic Valve ◽  
Heart Valves ◽  
Valve Prosthesis ◽  
Normal Functioning ◽  
The Past ◽  
Aortic Valve Prosthesis

Abstract Although it is no longer in production, the Starr–Edwards valve has successfully replaced hundreds of thousands of heart valves in the past 50 years of its use. We report on the case of a valve in the aortic position still functioning 49 years after implantation without replacement, showcasing the valve’s durability.

New Generation CoreValve EvolutTM R 23mm Aortic Valve Prosthesis: Initial Experience

2015 ◽  
Vol 68 (8) ◽  
pp. 721-722
Author(s):  
Antonio J. Muñoz-García ◽  
Isaac Pascual ◽  
Pablo Avanzas ◽  
Juan H. Alonso-Briales ◽  
César Morís ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Valve Prosthesis ◽  
Initial Experience ◽  
Aortic Valve Prosthesis ◽  
New Generation

scholarly journals Improvements of Procedural Results With a New-Generation Self-Expanding Transfemoral Aortic Valve Prosthesis in Comparison to the Old-Generation Device

2016 ◽  
Vol 30 (1) ◽  
pp. 72-78 ◽  
Author(s):  
Bruna Gomes ◽  
Nicolas A. Geis ◽  
Emmanuel Chorianopoulos ◽  
Benjamin Meder ◽  
Florian Leuschner ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Valve Prosthesis ◽  
Aortic Valve Prosthesis ◽  
New Generation

The new generation is coming. Percutaneous implantation of the fully repositionable Lotus® aortic valve prosthesis: the first Polish experience

2015 ◽  
pp. 80-84 ◽  
Author(s):  
Marek Grygier ◽  
Aleksander Araszkiewicz ◽  
Maciej Lesiak ◽  
Zofia Oko-Sarnowska ◽  
Olga Trojnarska ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Valve Prosthesis ◽  
Polish Experience ◽  
Aortic Valve Prosthesis ◽  
New Generation

RF59 PERCEVAL SUTURELESS AORTIC VALVE PROSTHESIS

2018 ◽  
Vol 19 ◽  
pp. e44
Author(s):  
E. Mikus ◽  
M. Pagliaro ◽  
S. Calvi ◽  
M. Panzavolta ◽  
E. Ramoni ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Valve Prosthesis ◽  
Aortic Valve Prosthesis

Passing a Mechanical Aortic Valve With a Short Tip Dilator to Facilitate Aortic Arch Endovascular Branched Repair

2021 ◽  
pp. 152660282110025
Author(s):  
Nikolaos Konstantinou ◽  
Sven Peterss ◽  
Jan Stana ◽  
Barbara Rantner ◽  
Ramin Banafsche ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Arch ◽  
Stent Graft ◽  
Mechanical Valve ◽  
Valve Prosthesis ◽  
Proper Position ◽  
Mechanical Aortic Valve ◽  
Aortic Replacement ◽  
Custom Made ◽  
Aortic Valve Prosthesis

Purpose To present a novel technique to successfully cross a mechanical aortic valve prosthesis. Technique A 55-year-old female patient with genetically verified Marfan syndrome presented with a 5-cm anastomotic aneurysm of the proximal aortic arch after previous ascending aortic replacement due to a type A aortic dissection in 2007. The patient also underwent mechanical aortic valve replacement in 1991. A 3-stage hybrid repair was planned. The first 2 steps included debranching of the supra-aortic vessels. In the third procedure, a custom-made double branched endovascular stent-graft with a short 35-mm introducer tip was implanted. The mechanical valve was passed with the tip of the dilator on the lateral site of the leaflet, without destructing the valve and with only mild symptoms of aortic insufficiency, as one leaflet continued to work. This allowed the implantation of the stent-graft directly distally of the coronary arteries. Postoperative computed tomography angiography showed no endoleaks and patent coronary and supra-aortic vessels. Conclusion Passing a mechanical aortic valve prosthesis at the proper position is feasible and allows adequate endovascular treatment in complex arch anatomy. However, caution should be taken during positioning of the endovascular graft as the tip may potentially damage the valve prosthesis.

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