scholarly journals Determining the effects of excess weight on renal cortical stiffness in children and adolescents with point Shear Wave Elastography

2021 ◽  
Author(s):  
Zehra Filiz Karaman ◽  
Fatih Kardas

Aim: To determine the early effects of excess weight on renal cortical stiffness in children and adolescents using point shear wave elastography (pSWE). Materials and methods: One hundred and forty-six overweight and obese children (43.2% male; mean age, 12.6±2.9 years: range 4.3-18) and 48 lean children (27.1% male: mean age, 12.4±3.4: range 4.8-18.9) were included in the study and control group, respectively. pSWE measurements of the two kidneys were performed. The mean value of shear wave velocity was compared between groups. Results: The mean shear wave velocity was 2.79±0.53 m/s for the control subjects and 3.09±0.59 m/s for the overweight-obese subjects. The differences between the two groups were sta-tistically significant (p=0.001). There was no correlation between shear wave velocity and age or depth. A positive correlation was found between shear wave velocity and body mass index, body mass index-standard deviation score. Conclusion: Renal cortical stiffness was higher in children with excess weight than in lean children. This study is the first attempt at applying pSWE to investigate the early adverse effects of excess weight.

2001 ◽  
Vol 36 (2) ◽  
pp. 363-372 ◽  
Author(s):  
T. Hermanns-Lê ◽  
F. Jonlet ◽  
A. Scheen ◽  
G.E. Piérard

2016 ◽  
Vol 41 (7) ◽  
pp. 1310-1316 ◽  
Author(s):  
Sabina Stumpf ◽  
◽  
Heike Jaeger ◽  
Tilmann Graeter ◽  
Suemeyra Oeztuerk ◽  
...  

2018 ◽  
Vol 20 (2) ◽  
pp. 141 ◽  
Author(s):  
Alpaslan Yavuz ◽  
Adem Yokus ◽  
Kerem Taken ◽  
Abdussamet Batur ◽  
Mesut Ozgokce ◽  
...  

Aims: To evaluate the reliability of testicular stiffness quantification using shear wave elastography in predicting the fertility potential of males and for the pre-diagnosis of disorders based upon sperm quantification. Material and methods: One hundred males between the ages of 19-49 years (mean age of 28.77±6.11), ninety of whom with complaints of infertility, were enrolled in this prospective study. Scrotal grey-scale, Doppler ultrasound (US), and mean testicular shear wave velocity quantifications (SWVQs) were performed. The volumes of testes, as well as the grade of varicocele if present, were recorded. The mean shear wave velocity values (SWVVs) of each testis and a mean testicular SWVV for each patient were calculated. The semen-analyses of patients were consecutively performed. Results: There were significant negative correlations between the mean testicular SWVVs of patients and their sperm counts or the testis volumes (r=-0.399, r=-0.565; p<0.01, respectively). A positive correlation was found between testicular volumes and sperm counts (r=0.491, p<0.01). The cut-off values regarding mean testicular SWVV to distinguish normal sperm count from azoospermia and oligozoospermia were 1.465 m/s (75.0% sensitivity and 75.0% specificity) and 1.328 m/s (64.3% sensitivity and 68.2% specificity), respectively, and the value to distinguish oligozoospermia from azoospermia was 1.528 m/s (66.7% sensitivity, 60.7% specificity). Conclusion: The mean testicular SWVQ using the ARFI shear wave technique was a reliable, non-invasive and acceptably stable method for predicting male infertility, especially related to sperm count issues. 


2019 ◽  
Vol 12 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Lisa Hackett ◽  
Ricardo Aveledo ◽  
Patrick H Lam ◽  
George AC Murrell

Introduction Shear wave elastography ultrasound is a relatively new technique that evaluates the tissue elasticity by applying an acoustic radiation force impulse. It is undetermined how reliable this modality is in assessing rotator cuff tendons. The aim of this study, therefore, was to evaluate the reliability of shear wave elastography ultrasound to assess the stiffness of normal and tendinopathic supraspinatus tendons. Methods An inter- and intra-rater reliability trial was carried out using shear wave elastography to assess the supraspinatus tendon at its distal insertion, by measuring shear wave velocity and elasticity. Twenty participants with a mean age of 37 (21–69) years old were evaluated. Ten subjects with normal supraspinatus tendon and 10 subjects with tendinopathic tendon were selected. The Virtual Touch Imaging Quantification program was used to generate the acoustic radiation force impulse and to obtain the elastography data. Three raters with different experience in conventional ultrasound were used for the inter-rater trial in normal tendons and the most experienced rater examined all subjects for the intra-rater reliability evaluation. Each rater obtained three readings in three different examinations per subject over a one-week period. Results The mean (±SEM) shear wave velocity for the normal supraspinatus tendon was 9.96 ± 0.02 m/s (=297 kPa), while in the tendinopathic supraspinatus tendon was 8.3 ± 0.2 m/s (=207 kPa) (p < 0.001). The intra-rater trial agreement was excellent, with an intraclass correlation coefficient = 0.96. In the inter-rater testing, the mean shear wave velocity in normal tendons was 9.90 ± 0.07 m/s (=294 kPa), with intraclass correlation coefficient = 0.45. Conclusion Shear wave elastography ultrasound was able to show that tendinopathic tendons were less stiff than normal tendons. It was a reliable imaging technique to assess the supraspinatus tendon, especially when used by a single experienced musculoskeletal sonographer.


2019 ◽  
Vol 35 (3) ◽  
pp. 182-187
Author(s):  
Amitabh Dashottar ◽  
Erin Montambault ◽  
Jeffrey R. Betz ◽  
Kevin D. Evans

Although ultrasound elastography is established as a reliable and valid tool for assessment of skeletal muscles, guidelines around the technical specifications, data selection, and acquisition parameters still lack consensus. One such parameter is the use of the quantification box (Q-box) that calculates the shear wave velocity/modulus, within a selected region of interest (ROI). Currently, no data compare the effect of the elastographic area within the ROI to the mean shear wave velocity calculations, using a Q-box. In this study, the mean shear wave velocity calculated over a smaller (single Q-box) ROI is compared to the mean shear wave velocity calculated over maximum area of elastogram, within a ROI. Comparison of mean shear wave velocity revealed a significant difference ( t = 2.79, P = .007) between the means calculated over maximum area of elastogram for only nonuniform elastograms. The rater agreement for the classification scheme was assessed (κ = 0.85). To prevent possible overestimation of shear wave velocities, it may be necessary to place the Q-box over the maximum elastographic area.


2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Takahiro Fukuhara ◽  
Eriko Matsuda ◽  
Yukari Endo ◽  
Ryohei Donishi ◽  
Shoichiro Izawa ◽  
...  

We sought to elucidate the correlation between shear wave velocity (SWV) and fibrosis in thyroid by precisely assessing pathological structures inside 5 × 5 mm2regions of interest (ROIs) of resected specimens, under conditions that excluded physical artifacts. The materials were unselected thyroid and lymph node specimens resected during thyroid surgery. Immediately after surgery, fresh unfixed thyroid and metastatic lymph node specimens were suspended in gel phantoms, and SWV was measured. Upon pathological examination of each specimen, the extent of fibrosis was graded as none, moderate, or severe. A total of 109 specimens were evaluated: 15 normal thyroid, 16 autoimmune thyroiditis, 40 malignant nodules, 19 benign thyroid nodules, and 19 metastatic lymph nodes. When all specimens were classified according to the degree of fibrosis determined by pathological imaging, the mean SWV was1.49±0.39 m/s for no fibrosis,2.13±0.66 m/s for moderate fibrosis, and2.68±0.82 m/s for severe fibrosis. The SWVs of samples with moderate and severe fibrosis were significantly higher than those of samples without fibrosis. The results of this study demonstrate that fibrosis plays an important role in determining stiffness, as measured by SWV in thyroid.


Author(s):  
Hiroaki Noro ◽  
Naokazu Miyamoto ◽  
Naotoshi Mitsukawa ◽  
Toshio Yanagiya

AbstractLower stiffness of the medial longitudinal arch is reportedly a risk factor for lower leg disorders. The plantar aponeurosis is considered essential to maintaining the medial longitudinal arch. It is therefore expected that medial longitudinal arch stiffness is influenced by plantar aponeurosis stiffness. However, this has not been experimentally demonstrated. We examined the relationship between the plantar aponeurosis stiffness and medial longitudinal arch stiffness in humans in vivo. Thirty young subjects participated in this study. The navicular height and shear wave velocity (an index of stiffness) of the plantar aponeurosis were measured in supine and single-leg standing positions, using B-mode ultrasonography and shear wave elastography, respectively. The medial longitudinal arch stiffness was calculated based on body weight, foot length, and the difference in navicular height between the supine and single-leg standing conditions (i. e., navicular drop). Shear wave velocity of the plantar aponeurosis in the supine and single-leg standing positions was not significantly correlated to medial longitudinal arch stiffness (spine: r=−0.14, P=0.45 standing: r=−0.16, P=0.41). The findings suggest that the medial longitudinal arch stiffness would be strongly influenced by the stiffness of foot structures other than the plantar aponeurosis.


2020 ◽  
Author(s):  
Lei Wang ◽  
Xi Xiang ◽  
Bihui Zhu ◽  
Li Qiu

Abstract Background: To measure the middle deltoid (MD) muscle elasticity during different shoulder abduction in healthy participants using shear wave elastography (SWE) and analyze the factors that may affect the MD elasticity, and then to establish the reference ranges of the normal MD elasticity during different shoulder abduction. Methods: Mean shear wave velocity (SWV) of the MD in 70 healthy participants were evaluated at left and right shoulder 0° and 90° abduction (L0°, R0°, L90°, R90°) using SWE, and potential factors that may affect MD elasticity including gender, MD thickness, age, body mass index were analyzed. Normal reference ranges of MD elasticity were calculated using normal distribution method. Results: Mean SWV was statistically significantly higher at L90° than L0°, higher at R90° than R0°, higher at R0° than L0°, and higher at R90° than L90° (all p< 0.0001). Mean SWV was significantly higher in males at both L0° (p< 0.05) and R0° (p< 0.01) than in females. Neither MD thickness, age nor body mass index influenced MD elasticity. Normal reference ranges of the MD elasticity were 2.4-3.1 m/s in males and 2.2-2.9 m/s in females at L0° and 2.5-3.3 m/s in males and 2.4-3.2 m/s in females at R0°, and were 4.9-6.7 m/s at L90°, 5.2-7.1 m/s at R90° for both males and females. Conclusions: Our results suggest that the normal MD elasticity at L0°, R0°, L90°, R90° are different and gender should be considered when determining the reference ranges of normal MD elasticity at L0° and R0° with SWE. These values may provide quantitative baseline measurements for assessment of the normal MD elasticity.


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