Three-dimensional photoacoustic/ultrasound handheld scanner for clinical translation

2020 ◽  
Author(s):  
Changyeop Lee ◽  
Wonseok Choi ◽  
Jeesu Kim ◽  
Chulhong Kim
Keyword(s):  
Three Dimensional ◽  
Clinical Translation ◽  
Handheld Scanner

Using a 3D handheld scanner to capture trochlear groove shape: proof of concept study

2021 ◽  
Author(s):  
J Mistry ◽  
CB Hing ◽  
S Harris
Keyword(s):  
Inclination Angle ◽  
Interobserver Reliability ◽  
Intraclass Correlation ◽  
Three Dimensional ◽  
Trochlear Groove ◽  
Sulcus Angle ◽  
Custom Software ◽  
Test Retest Reliability ◽  
Time Planning ◽  
Handheld Scanner

Introduction Trochleoplasty is a surgical procedure used to treat patellar instability by modifying the trochlear groove. Analysis of the groove with a handheld scanner would enable accurate real-time planning and facilitate tailormade correction. We aimed to measure trochlear depth, sulcus angle, trochlear facet ratio, trochlear angle and lateral trochlear inclination angle and to establish inter- and intra-rater reliability for knee models to determine reliability and repeatability. Methods The trochlear grooves of three knee models were scanned by two investigators. Three-dimensional reference models were created and surface-matched. Custom software was used to determine the desired parameters. The intraclass correlation coefficient (ICC) was used to determine test–retest reliability and the parameter results for each model that showed best reproducibility. Results There was good interobserver reliability (trochlear depth, 1.0mm; sulcus angle, 2.7°; trochlear angle, 4.0°; lateral trochlear inclination angle, 4.0°), except in the trochlear facet ratio (32.0%) of one knee model. With outliers removed, the ICC was moderate to excellent in 73.34% of measurements, with trochlear depth showing the best reproducibility. Discussion This feasibility study showed a handheld scanner in conjunction with supporting software can measure trochlear parameters with good to excellent inter- and intra-observer reliability.

Visual weld inspection enters the new millennium

Sensor Review ◽  
2001 ◽  
Vol 21 (4) ◽  
pp. 278-282 ◽  
Author(s):  
Jeffrey Noruk
Keyword(s):  
Automotive Industry ◽  
Visual Inspection ◽  
Three Dimensional ◽  
Sensor Technology ◽  
Production Lines ◽  
Inspection Systems ◽  
Weld Inspection ◽  
Welding Consumables ◽  
Handheld Scanner ◽  
Welding Processes

New weld inspection methods superceding visual inspection are presented. Laser‐based sensor technology contained in a handheld scanner for pre‐ and post‐weld inspection enables measurement of joint preparations or finished welds and validation of their geometry against pre‐set limits, as well as the analysis of three‐dimensional images of weld beads. The range of laser‐based sensor equipment available extends to full robotic weld inspection systems, which are applied in arc and laser welding processes on production lines, such as in the automotive industry. The benefits of these systems include higher repeatability, a permanent record for generating trending information, and the production of data helpful in reducing welding consumables used, resulting in significant savings to manufacturers.

scholarly journals High-speed three-dimensional photoacoustic computed tomography for preclinical research and clinical translation

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Li Lin ◽  
Peng Hu ◽  
Xin Tong ◽  
Shuai Na ◽  
Rui Cao ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Speed ◽  
Three Dimensional ◽  
Biological Tissues ◽  
Clinical Translation ◽  
Breath Hold ◽  
Human Breast ◽  
Preclinical Research ◽  
Imaging Depth

AbstractPhotoacoustic computed tomography (PACT) has generated increasing interest for uses in preclinical research and clinical translation. However, the imaging depth, speed, and quality of existing PACT systems have previously limited the potential applications of this technology. To overcome these issues, we developed a three-dimensional photoacoustic computed tomography (3D-PACT) system that features large imaging depth, scalable field of view with isotropic spatial resolution, high imaging speed, and superior image quality. 3D-PACT allows for multipurpose imaging to reveal detailed angiographic information in biological tissues ranging from the rodent brain to the human breast. In the rat brain, we visualize whole brain vasculatures and hemodynamics. In the human breast, an in vivo imaging depth of 4 cm is achieved by scanning the breast within a single breath hold of 10 s. Here, we introduce the 3D-PACT system to provide a unique tool for preclinical research and an appealing prototype for clinical translation.

The orbit of Pluto over a long interval of time

1966 ◽  
Vol 25 ◽  
pp. 227-229 ◽  
Author(s):  
D. Brouwer
Keyword(s):  
Periodic Orbit ◽  
Numerical Integration ◽  
Restricted Problem ◽  
Three Dimensional ◽  
The Third ◽  
Circular Restricted Problem ◽  
Resonance Relation

The paper presents a summary of the results obtained by C. J. Cohen and E. C. Hubbard, who established by numerical integration that a resonance relation exists between the orbits of Neptune and Pluto. The problem may be explored further by approximating the motion of Pluto by that of a particle with negligible mass in the three-dimensional (circular) restricted problem. The mass of Pluto and the eccentricity of Neptune's orbit are ignored in this approximation. Significant features of the problem appear to be the presence of two critical arguments and the possibility that the orbit may be related to a periodic orbit of the third kind.

Conformation of Ribosomes from Escherichia Coli

1974 ◽  
Vol 32 ◽  
pp. 210-211
Author(s):  
M. Boublik ◽  
W. Hellmann ◽  
F. Jenkins
Keyword(s):  
Binding Sites ◽  
Ribosomal Proteins ◽  
Fluorescent Dyes ◽  
Protein Biosynthesis ◽  
Three Dimensional ◽  
Spatial Arrangement ◽  
Dimensional Structure ◽  
Complete Understanding ◽  
And Function

The present knowledge of the three-dimensional structure of ribosomes is far too limited to enable a complete understanding of the various roles which ribosomes play in protein biosynthesis. The spatial arrangement of proteins and ribonuclec acids in ribosomes can be analysed in many ways. Determination of binding sites for individual proteins on ribonuclec acid and locations of the mutual positions of proteins on the ribosome using labeling with fluorescent dyes, cross-linking reagents, neutron-diffraction or antibodies against ribosomal proteins seem to be most successful approaches. Structure and function of ribosomes can be correlated be depleting the complete ribosomes of some proteins to the functionally inactive core and by subsequent partial reconstitution in order to regain active ribosomal particles.

Ultrastructural Investigations of the Contractile Filaments of Amoebae

1974 ◽  
Vol 32 ◽  
pp. 188-189
Author(s):  
P.L. Moore
Keyword(s):  
Cytoplasmic Streaming ◽  
Three Dimensional ◽  
Freeze Fracture ◽  
Amoeboid Movement ◽  
Different Types ◽  
Chemical Conditions ◽  
Complete Interpretation

Previous freeze fracture results on the intact giant, amoeba Chaos carolinensis indicated the presence of a fibrillar arrangement of filaments within the cytoplasm. A complete interpretation of the three dimensional ultrastructure of these structures, and their possible role in amoeboid movement was not possible, since comparable results could not be obtained with conventional fixation of intact amoebae. Progress in interpreting the freeze fracture images of amoebae required a more thorough understanding of the different types of filaments present in amoebae, and of the ways in which they could be organized while remaining functional.The recent development of a calcium sensitive, demembranated, amoeboid model of Chaos carolinensis has made it possible to achieve a better understanding of such functional arrangements of amoeboid filaments. In these models the motility of demembranated cytoplasm can be controlled in vitro, and the chemical conditions necessary for contractility, and cytoplasmic streaming can be investigated. It is clear from these studies that “fibrils” exist in amoeboid models, and that they are capable of contracting along their length under conditions similar to those which cause contraction in vertebrate muscles.

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