High-speed digital video imaging system to record cardiac action potentials

2001 ◽  
Author(s):  
Akira Mishima ◽  
Tatsuhiko Arafune ◽  
Ken Masamune ◽  
Ichiro Sakuma ◽  
Takeyoshi Dohi ◽  
...  
Keyword(s):  
Action Potentials ◽  
High Speed ◽  
Digital Video ◽  
Imaging System ◽  
Video Imaging ◽  
Cardiac Action

High-speed gear-failure digital video imaging system

1997 ◽  
Author(s):  
Howard Broughton ◽  
James J. Sims
Keyword(s):  
High Speed ◽  
Digital Video ◽  
Imaging System ◽  
Video Imaging

A three-camera multispectral digital video imaging system

1995 ◽  
Vol 54 (3) ◽  
pp. 333-337 ◽  
Author(s):  
J.H. Everitt ◽  
D.E. Escobar ◽  
I. Cavazos ◽  
J.R. Noriega ◽  
M.R. Davis
Keyword(s):  
Digital Video ◽  
Imaging System ◽  
Video Imaging

A Twelve-Band Airborne Digital Video Imaging System (ADVIS)

1998 ◽  
Vol 66 (2) ◽  
pp. 122-128 ◽  
Author(s):  
D.E. Escobar ◽  
J.H. Everitt ◽  
J.R. Noriega ◽  
I. Cavazos ◽  
M.R. Davis
Keyword(s):  
Digital Video ◽  
Imaging System ◽  
Video Imaging

scholarly journals Characterising the dynamics of expirated bloodstain pattern formation using high-speed digital video imaging

2010 ◽  
Vol 125 (6) ◽  
pp. 757-762 ◽  
Author(s):  
Andrea E. Donaldson ◽  
Nicole K. Walker ◽  
Iain L. Lamont ◽  
Stephen J. Cordiner ◽  
Michael C. Taylor
Keyword(s):  
Pattern Formation ◽  
High Speed ◽  
Digital Video ◽  
Video Imaging ◽  
Bloodstain Pattern

New Molecular Scaffolds for Fluorescent Voltage Indicators

2018 ◽  
Author(s):  
Steven Boggess ◽  
Shivaani Gandhi ◽  
Brian Siemons ◽  
Nathaniel Huebsch ◽  
Kevin Healy ◽  
...  
Keyword(s):  
Membrane Potential ◽  
Action Potentials ◽  
Induced Pluripotent Stem Cell ◽  
Molecular Wire ◽  
Voltage Sensing ◽  
Design Synthesis ◽  
Cardiac Action ◽  
Action Potential Waveform ◽  
Induced Pluripotent ◽  
Voltage Sensing Domain

<div> <p>The ability to non-invasively monitor membrane potential dynamics in excitable cells like neurons and cardiomyocytes promises to revolutionize our understanding of the physiology and pathology of the brain and heart. Here, we report the design, synthesis, and application of a new class of fluorescent voltage indicator that makes use of a fluorene-based molecular wire as a voltage sensing domain to provide fast and sensitive measurements of membrane potential in both mammalian neurons and human-derived cardiomyocytes. We show that the best of the new probes, fluorene VoltageFluor 2 (fVF 2) readily reports on action potentials in mammalian neurons, detects perturbations to cardiac action potential waveform in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes, shows a substantial decrease in phototoxicity compared to existing molecular wire-based indicators, and can monitor cardiac action potentials for extended periods of time. Together, our results demonstrate the generalizability of a molecular wire approach to voltage sensing and highlights the utility of fVF 2 for interrogating membrane potential dynamics.</p> </div>

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