Development of fibrin-free intraocular lens with photochemical surface modification

2004 ◽  
Author(s):  
Yuji Sato ◽  
Katsuya Tanizawa ◽  
Hiroyuki Anai ◽  
Nobuhiro Sato ◽  
Yuki Sato ◽  
...  
Keyword(s):  
Surface Modification ◽  
Intraocular Lens

Drug Eluting Intraocular Lens Surface Modification for PCO Prevention

2018 ◽  
Vol 24 ◽  
pp. 40-44 ◽  
Author(s):  
Yuemei Han ◽  
Xu Xu ◽  
Yuqin Wang ◽  
Sihao Liu ◽  
Xia Zhao ◽  
...  
Keyword(s):  
Surface Modification ◽  
Intraocular Lens ◽  
Drug Eluting ◽  
Lens Surface

VUV-photon Induced Formation of Hydrophilic and Hydrophobic Micro Domains Structure on Intraocular Lens Surface for Blocking after Cataract

2007 ◽  
Vol 1054 ◽  
Author(s):  
Yuji Sato ◽  
Kenji Kawai ◽  
Mikio Sasoh ◽  
Hiroaki Ozaki ◽  
Takeo Ohki ◽  
...  
Keyword(s):  
Surface Modification ◽  
Infrared Spectroscopy ◽  
Intraocular Lens ◽  
Laser Light ◽  
Ultra Violet ◽  
Hydrophobic Surface ◽  
Sample Surface ◽  
Oh Groups ◽  
Ft Ir ◽  
Lens Surface

ABSTRACTA micro domain structure, which hydrophilic and hydrophobic groups were arrayed alternately, was formed on the surface of an intraocular lens [IOL] by using ultra violet rays [VUV]. With this technique, the IOL that is free from fibrin has been developed. In order to substitute the hydrophilic groups in matrix-form on the surface, an ArF laser light was then irradiated on the hydrophobic surface in the presence of water for the −OH groups, through the 50-micrometer dot-patterned reticle. With this selective photochemical surface modification, the hydrophilic and hydrophobic groups were arrayed alternately on the sample surface. The modified IOL was soaked in 0.1-wt % fibrin solutions, and the fibrin-sticking rate was measured by using an infrared spectroscopy [FT-IR]. It results that the absorption coefficient of amide band reached to 0.0006, decreasing to one-six of non-treatment sample's.

scholarly journals Facile multifunctional IOL surface modification via poly(PEGMA-co-GMA) grafting for posterior capsular opacification inhibition

RSC Advances ◽  
2021 ◽  
Vol 11 (17) ◽  
pp. 9840-9848
Author(s):  
Jiayi Xia ◽  
Duoduo Lu ◽  
Yuemei Han ◽  
Jiahao Wang ◽  
Yueze Hong ◽  
...  
Keyword(s):  
Surface Modification ◽  
Intraocular Lens ◽  
Surface Coating ◽  
Posterior Capsular Opacification ◽  
Drug Eluting ◽  
Lens Surface

Drug eluting and hydrophilic intraocular lens surface coating was facilely fabricated via poly(PEGMA-co-GMA) grafting. Such a multifunctional coating reduced posterior capsular opacification incidence after implantation effectively.

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