In Part 1 by Mr J. Shapiro, the merits of the chosen combined shielding design are explained. The geometry of the radiation head is given including the source movement mechanism. The problem, basic principle and engineering embodiment of the radiation beam definition and control mechanism are discussed. The fundamental approach and engineering solutions of the radiation head alignment system are described. The remote control of the unit and the treatment sequence are briefly reviewed. In Part 2 by Dr A. D. O'Connor, the radioactive isotopes suitable for use in large treatment units in radiotherapy are reviewed with special reference to cobalt 60. In comparison with X-ray generators of such quality, such units are more reliable. The features of design of a unit desirable for isotope teletherapy are set out. The methods of treatment planning and execution are described and the advantages obtained from the Servotec Canterbury unit enumerated.