Progressive hearing loss in mouse models of presbycusis: Influence of an augmented acoustic environment and of gender

2000 ◽  
Vol 107 (5) ◽  
pp. 2797-2798
Author(s):  
James F. Willott
2020 ◽  
Author(s):  
Adam C. Dziorny ◽  
Luisa L. Scott ◽  
Anne E. Luebke ◽  
Joseph P. Walton

AbstractCongenital sensorineural hearing loss (SNHL) affects thousands of infants each year and results in significant delays in speech and language development. Previous studies have shown that early exposure to a simple augmented acoustic environment (AAE) can limit the effects of progressive SNHL on hearing sensitivity. However, SNHL is also accompanied by “hidden hearing loss” that is not assessed on standard audiological exams, such as reduced temporal processing acuity. To assess whether sound therapy may improve these hidden deficits, a mouse model of congenital SNHL was exposed to simple or temporally complex AAE. Peripheral function and sound sensitivity in auditory midbrain neurons improved following exposure to both types of AAE. However, only exposure to a novel, temporally complex AAE significantly improved a measure of temporal processing acuity, neural gap-in-noise detection in the auditory midbrain. These experiments suggest that targeted sound therapy may improve hearing outcomes for children suffering from congenital SNHL.


2009 ◽  
Vol 119 (7) ◽  
pp. 1374-1379 ◽  
Author(s):  
Chiemi Tanaka ◽  
Eric C. Bielefeld ◽  
Guang-Di Chen ◽  
Manna Li ◽  
Donald Henderson

2020 ◽  
Vol 26 (1) ◽  
pp. 31-36
Author(s):  
Md Zakaria Sarkar ◽  
AHM Ferdows Nur ◽  
Utpal Kumar Dutta ◽  
Muhammad Rafiqul Islam ◽  
Debabrota Roy ◽  
...  

Objective: The aim of this study was to evaluate hearing outcome after stapedotomy in patients with Otosclerosis. Methods: This cross sectional study was carried out from July 2017 to January 2019 in National Institute of ENT, Unit V. About 22 patients with Otosclerosis were included in this study. Diagnosis of Otosclerosis was based on the history, medical status with Otoscopy, Tuning fork tests and Audiometric tests. We compiled data on the pre and post operative air-bone gap (ABG) at 0.5, 1, 2 KHZ. The ABG was Calculated using AC and BC thresholds on the same audiogram. Post operative hearing gain was then Calculated from the ABG before the operation minus the ABG of the last follow up examination Results: In this study most of the cases were age group 14-30 years (72.7%), female (54.5%). Most common symptoms was progressive hearing loss, tinnitus (77.8%).The average preoperative hearing loss in this study was (AC) was 48.31±7.68. The average post opt. hearing (AC) at follow up was 28.95±10.30 with an average hearing gain of 15.40±8.53 dB which was significant. The average pre-operative ABG was 28.99 dB ± 8.10. The average post opt. ABG was analyzed at 1 follow up showed ABG 13.18±8.09 dB which was found to be significant. Conclusion: Stapedotomy is an effective surgical procedure for the treatment of otosclerosis which leads to improvement in patient’s quality of life. A favorable hearing outcome can be obtained by the combination of experienced hands with minimal surgical trauma and appropriate surgical technique. Bangladesh J Otorhinolaryngol; April 2020; 26(1): 31-36


2017 ◽  
Vol 28 ◽  
Author(s):  
Abdellah Taous ◽  
Maha Aït Berri ◽  
Mohamed Sinaa ◽  
Issam En-nafaa ◽  
Karim Nadour ◽  
...  

PLoS ONE ◽  
2011 ◽  
Vol 6 (3) ◽  
pp. e17607 ◽  
Author(s):  
Shehnaaz S. M. Manji ◽  
Louise H. Williams ◽  
Kerry A. Miller ◽  
Lisa M. Ooms ◽  
Melanie Bahlo ◽  
...  

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