Ultrafast high frequency ultrasound Doppler imaging and its biomedical applications

2019 ◽  
Vol 146 (4) ◽  
pp. 2900-2900
Author(s):  
Chih-Chung Huang
Keyword(s):  
High Frequency ◽  
Biomedical Applications ◽  
Doppler Imaging ◽  
High Frequency Ultrasound ◽  
Ultrasound Doppler ◽  
Frequency Ultrasound

scholarly journals High-Frequency Ultrasound Doppler System for Biomedical Applications with a 30-MHz Linear Array

2008 ◽  
Vol 34 (4) ◽  
pp. 638-646 ◽  
Author(s):  
Xiaochen Xu ◽  
Lei Sun ◽  
Jonathan M. Cannata ◽  
Jesse T. Yen ◽  
K. Kirk Shung
Keyword(s):  
High Frequency ◽  
Biomedical Applications ◽  
Linear Array ◽  
High Frequency Ultrasound ◽  
Ultrasound Doppler ◽  
Doppler System ◽  
Frequency Ultrasound

scholarly journals Monitoring of Adult Zebrafish Heart Regeneration Using High-Frequency Ultrasound Spectral Doppler and Nakagami Imaging

Sensors ◽  
2019 ◽  
Vol 19 (19) ◽  
pp. 4094 ◽  
Author(s):  
Sunmi Yeo ◽  
Changhan Yoon ◽  
Ching-Ling Lien ◽  
Tai-Kyong Song ◽  
K. Kirk Shung
Keyword(s):  
High Frequency ◽  
Doppler Imaging ◽  
Adult Zebrafish ◽  
High Frequency Ultrasound ◽  
In Vivo Experiments ◽  
Longitudinal Measurements ◽  
Array Transducer ◽  
Spectral Doppler ◽  
Frequency Ultrasound

This paper reports the feasibility of Nakagami imaging in monitoring the regeneration process of zebrafish hearts in a noninvasive manner. In addition, spectral Doppler waveforms that are typically used to access the diastolic function were measured to validate the performance of Nakagami imaging. A 30-MHz high-frequency ultrasound array transducer was used to acquire backscattered echo signal for spectral Doppler and Nakagami imaging. The performances of both methods were validated with flow and tissue-mimicking phantom experiments. For in vivo experiments, both spectral Doppler and Nakagami imaging were simultaneously obtained from adult zebrafish with amputated hearts. Longitudinal measurements were performed for five zebrafish. From the experiments, the E/A ratio measured using spectral Doppler imaging increased at 3 days post-amputation (3 dpa) and then decreased to the value before amputation, which were consistent with previous studies. Similar results were obtained from the Nakagami imaging where the Nakagami parameter value increased at 3 dpa and decreased to its original value. These results suggested that the Nakagami and spectral Doppler imaging would be useful techniques in monitoring the regeneration of heart or tissues.

High‐frequency ultrasound Doppler velocimetry measurements of intra‐cochlear structures in human temporal bones.

2010 ◽  
Vol 128 (4) ◽  
pp. 2305-2305
Author(s):  
Jeremy Brown ◽  
Zahra Torbatian ◽  
Phil Garland ◽  
Rob Adamson ◽  
Rene Van Wijhe ◽  
...  
Keyword(s):  
High Frequency ◽  
Doppler Velocimetry ◽  
High Frequency Ultrasound ◽  
Ultrasound Doppler ◽  
Temporal Bones ◽  
Frequency Ultrasound

scholarly journals Motor cortex neurovascular coupling: inputs from ultra–high-frequency ultrasound imaging in humans

2019 ◽  
Vol 131 (5) ◽  
pp. 1632-1638 ◽  
Author(s):  
Fabien Almairac ◽  
Denys Fontaine ◽  
Thomas Demarcy ◽  
Hervé Delingette ◽  
Stéphanie Beuil ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Motor Cortex ◽  
High Frequency ◽  
Cortical Area ◽  
Neurovascular Coupling ◽  
Doppler Imaging ◽  
High Frequency Ultrasound ◽  
Local Cerebral Blood Flow ◽  
Frequency Ultrasound

OBJECTIVENeurovascular coupling reflects the link between neural activity and changes in cerebral blood flow. Despite many technical advances in functional exploration of the brain, including functional MRI, there are only a few reports of direct evidence of neurovascular coupling in humans. The authors aimed to explore, for the first time in humans, the local cerebral blood flow of the primary motor cortex using ultra–high-frequency ultrasound (UHF-US) Doppler imaging to detect low blood flow velocity (1 mm/sec).METHODSFour consecutive patients underwent awake craniotomy for glioma resection using cortical direct electrostimulation for brain mapping. The primary motor cortical area eliciting flexion of the contralateral forearm was identified. UHF-US color Doppler imaging of this cortical area was acquired at rest, during repeated spontaneous forearm flexion, and immediately after the movement’s termination. In each condition, the surface areas of the detectable vessels were measured after extraction of non–zero-velocity colored pixels and summed.RESULTSDuring movement, local cerebral blood flow increased significantly by 14.4% (range 5%–30%) compared with baseline. Immediately after the termination of movements, the local hyperemia decreased significantly by 8.6% (range 1.9%–15.7%).CONCLUSIONSTo the authors’ knowledge, this study is the first to provide a real-time demonstration of the neurovascular coupling in the human cortex by ultrasound imaging. They assume that UHF-US may be used to gather original and advanced data on brain functioning, which could be used to help in the identification of functional cortical areas during brain surgery.Clinical trial registration no.: NCT03179176 (clinicaltrials.gov)

Evaluation of Hand Tendon Movement by Using High-Frequency Ultrasound Vector Doppler Imaging

2020 ◽  
Vol 67 (10) ◽  
pp. 2945-2952
Author(s):  
Min-Yuan Wang ◽  
Tai-Hua Yang ◽  
Hsin Huang ◽  
Hsiu-Yun Hsu ◽  
Li-Chieh Kuo ◽  
...  
Keyword(s):  
High Frequency ◽  
Doppler Imaging ◽  
High Frequency Ultrasound ◽  
Frequency Ultrasound
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