Metabolism, Pharmacokinetics, and Excretion of a Nonpeptidic Substance P Receptor Antagonist, Ezlopitant, in Normal Healthy Male Volunteers: Characterization of Polar Metabolites by Chemical Derivatization with Dansyl Chloride

2007 ◽  
Vol 35 (7) ◽  
pp. 1071-1080 ◽  
Author(s):  
Chandra Prakash ◽  
John O'Donnell ◽  
S. Cyrus Khojasteh-Bakht
Keyword(s):  
Substance P ◽  
Receptor Antagonist ◽  
Dansyl Chloride ◽  
Chemical Derivatization ◽  
Healthy Male ◽  
Healthy Male Volunteers ◽  
Male Volunteers ◽  
Polar Metabolites ◽  
Substance P Receptor

Pharmacokinetic characterization of the novel oral prenyl transferase inhibitor AZD3409: The first analysis in healthy male volunteers

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 3172-3172 ◽  
Author(s):  
P. McCormack ◽  
M. Macpherson ◽  
D. Wilson ◽  
A. Lindsay ◽  
T. Parry ◽  
...  
Keyword(s):  
The Novel ◽  
Healthy Male ◽  
Healthy Male Volunteers ◽  
Male Volunteers ◽  
Prenyl Transferase

Pharmacokinetic characterization of the novel oral prenyl transferase inhibitor AZD3409: The first analysis in healthy male volunteers

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 3172-3172
Author(s):  
P. McCormack ◽  
M. Macpherson ◽  
D. Wilson ◽  
A. Lindsay ◽  
T. Parry ◽  
...  
Keyword(s):  
The Novel ◽  
Healthy Male ◽  
Healthy Male Volunteers ◽  
Male Volunteers ◽  
Prenyl Transferase

Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites

2015 ◽  
Vol 43 (8) ◽  
pp. 1190-1207 ◽  
Author(s):  
Steven Lacy ◽  
Bih Hsu ◽  
Dale Miles ◽  
Dana Aftab ◽  
Ronghua Wang ◽  
...  
Keyword(s):  
Healthy Male ◽  
Healthy Male Volunteers ◽  
Male Volunteers
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