Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase

Sarah R. Hunter; Alex Vonk; Anne K. Mullen Grey; David S. Riddick

doi:10.1124/dmd.116.073833

Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase

Drug Metabolism and Disposition ◽

10.1124/dmd.116.073833 ◽

2016 ◽

Vol 45 (2) ◽

pp. 118-129 ◽

Cited By ~ 10

Author(s):

Sarah R. Hunter ◽

Alex Vonk ◽

Anne K. Mullen Grey ◽

David S. Riddick

Keyword(s):

Cytochrome P450 ◽

Glucocorticoid Receptor ◽

Aryl Hydrocarbon Receptor ◽

Pregnane X Receptor ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Aryl Hydrocarbon ◽

Cytochrome P450 Oxidoreductase

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Role of glucocorticoid receptor and pregnane X receptor in dexamethasone induction of rat hepatic aryl hydrocarbon receptor nuclear translocator and NADPH‐cytochrome P450 oxidoreductase (LB597)

The FASEB Journal ◽

10.1096/fasebj.28.1_supplement.lb597 ◽

2014 ◽

Vol 28 (S1) ◽

Author(s):

David Riddick ◽

Sarah Hunter ◽

Alex Vonk

Keyword(s):

Cytochrome P450 ◽

Glucocorticoid Receptor ◽

Aryl Hydrocarbon Receptor ◽

Pregnane X Receptor ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Aryl Hydrocarbon ◽

Cytochrome P450 Oxidoreductase

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Role of the Conserved Phenylalanine 181 of NADPH−Cytochrome P450 Oxidoreductase in FMN Binding and Catalytic Activity†

Biochemistry ◽

10.1021/bi011147l ◽

2001 ◽

Vol 40 (45) ◽

pp. 13439-13447 ◽

Cited By ~ 9

Author(s):

Mark J. I. Paine ◽

Steven Ayivor ◽

Andrew Munro ◽

Pascale Tsan ◽

Lu-Yun Lian ◽

...

Keyword(s):

Cytochrome P450 ◽

Catalytic Activity ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Role of Acidic Residues in the Interaction of NADPH-Cytochrome P450 Oxidoreductase with Cytochrome P450 and Cytochromec

Journal of Biological Chemistry ◽

10.1074/jbc.270.46.27475 ◽

1995 ◽

Vol 270 (46) ◽

pp. 27475-27480 ◽

Cited By ~ 101

Author(s):

Anna L. Shen ◽

Charles B. Kasper

Keyword(s):

Cytochrome P450 ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase ◽

Acidic Residues

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Role of Ser457 of NADPH−Cytochrome P450 Oxidoreductase in Catalysis and Control of FAD Oxidation−Reduction Potential†

Biochemistry ◽

10.1021/bi960587n ◽

1996 ◽

Vol 35 (29) ◽

pp. 9451-9459 ◽

Cited By ~ 22

Author(s):

Anna L. Shen ◽

Charles B. Kasper

Keyword(s):

Cytochrome P450 ◽

Reduction Potential ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Oxidation Reduction ◽

Oxidation Reduction Potential ◽

Cytochrome P450 Oxidoreductase ◽

And Control

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Mosquito NADPH-cytochrome P450 oxidoreductase: kinetics and role of phenylalanine amino acid substitutions at leu86 and leu219 in CYP6AA3-mediated deltamethrin metabolism

Archives of Insect Biochemistry and Physiology ◽

10.1002/arch.20354 ◽

2010 ◽

pp. n/a-n/a

Author(s):

Songklod Sarapusit ◽

Sirikun Pethuan ◽

Pornpimol Rongnoparut

Keyword(s):

Cytochrome P450 ◽

Amino Acid ◽

Amino Acid Substitutions ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer

Biochemistry ◽

10.1021/acs.biochem.7b01102 ◽

2018 ◽

Vol 57 (6) ◽

pp. 945-962 ◽

Cited By ~ 5

Author(s):

Chuanwu Xia ◽

Freeborn Rwere ◽

Sangchoul Im ◽

Anna L. Shen ◽

Lucy Waskell ◽

...

Keyword(s):

Cytochrome P450 ◽

Hydride Transfer ◽

Kinetic Studies ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Loop Dynamics ◽

Cytochrome P450 Oxidoreductase

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Amphipol-facilitated Elucidation of the Functional Tetrameric Complex of Full-length Cytochrome P450 CYP2B4 and NADPH-Cytochrome-P450 Oxidoreductase

Journal of Biological Chemistry ◽

10.1016/j.jbc.2021.100645 ◽

2021 ◽

pp. 100645

Author(s):

Shen Cheng ◽

Zhiyuan Bo ◽

Paul Hollenberg ◽

Yoichi Osawa ◽

Haoming Zhang

Keyword(s):

Cytochrome P450 ◽

Full Length ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase ◽

Tetrameric Complex

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NADPH-cytochrome P450 oxidoreductase from the chicken (Gallus gallus): Sequence characterization, functional expression and kinetic study

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology ◽

10.1016/j.cbpc.2010.08.005 ◽

2011 ◽

Vol 153 (1) ◽

pp. 53-59 ◽

Cited By ~ 1

Author(s):

Xiaojie Zhou ◽

Mei Li ◽

Chengfa Sheng ◽

Xinghui Qiu

Keyword(s):

Cytochrome P450 ◽

Kinetic Study ◽

Functional Expression ◽

Gallus Gallus ◽

Sequence Characterization ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling

Toxicological Sciences ◽

10.1093/toxsci/kfv177 ◽

2015 ◽

Vol 148 (1) ◽

pp. 261-275 ◽

Cited By ~ 8

Author(s):

Philippe Briolotti ◽

Laurent Chaloin ◽

Patrick Balaguer ◽

Franck Da Silva ◽

Veronika Tománková ◽

...

Keyword(s):

Cytochrome P450 ◽

Aryl Hydrocarbon Receptor ◽

Kinase Inhibitors ◽

Glycogen Synthase ◽

Pregnane X Receptor ◽

Human Hepatocytes ◽

Glycogen Synthase Kinase ◽

Receptor Signaling ◽

Aryl Hydrocarbon ◽

P450 Expression

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Regulation of NADPH‐cytochrome P450 oxidoreductase by glucocorticoids in rat liver

The FASEB Journal ◽

10.1096/fasebj.27.1_supplement.lb627 ◽

2013 ◽

Vol 27 (S1) ◽

Author(s):

Alex Vonk ◽

David S Riddick

Keyword(s):

Cytochrome P450 ◽

Rat Liver ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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