Acetaminophen Recruits Spinal p42/p44 MAPKs and GH/IGF-1 Receptors to Produce Analgesia via the Serotonergic System

2006 ◽  
Vol 71 (2) ◽  
pp. 407-415 ◽  
Author(s):  
Jérôme Bonnefont ◽  
Laurence Daulhac ◽  
Monique Etienne ◽  
Eric Chapuy ◽  
Christophe Mallet ◽  
...  
Keyword(s):  
Serotonergic System

Serotonergic System and Its Role in Epilepsy and Neuropathic Pain Treatment: A Review Based on Receptor Ligands

2015 ◽  
Vol 21 (13) ◽  
pp. 1723-1740 ◽  
Author(s):  
Katarzyna Panczyk ◽  
Sylwia Go.lda ◽  
Anna Waszkielewicz ◽  
Dorota Zelaszczyk ◽  
Agnieszka Gunia-Krzyz.ak ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Pain Treatment ◽  
Serotonergic System ◽  
Receptor Ligands

Genetics, Parenting, and Moral Development

2019 ◽  
pp. 106-128
Author(s):  
Dana Vertsberger ◽  
Salomon Israel ◽  
Ariel Knafo-Noam
Keyword(s):  
Moral Development ◽  
Moral Reasoning ◽  
Prosocial Behavior ◽  
Dopaminergic System ◽  
Molecular Genetic ◽  
Parental Influences ◽  
Serotonergic System ◽  
Social Situations ◽  
Gene Environment ◽  
The Way

This chapter reviews findings regarding genetic and parental influences on moral development, and is organized according to three morally relevant components: cognitive, affective, and behavioral. The cognitive component refers to the conceptualization of right and wrong, and specifically moral reasoning and values. The affective component refers to feelings related to reactions to social situations and evaluations of chosen actions, focusing on emotions such as empathy, guilt, and pride. The behavioral component refers to the way individuals choose to behave, and specifically to prosocial behavior. We review relevant quantitative and molecular genetic designs, and particularly four neurobiological systems: the dopaminergic system, the oxytocinergic and vasopressinergic systems, and the serotonergic system, which have been found to be associated with moral development. In addition, we review parents’ influences on moral development, in the context of gene-environment interactions and correlations.

scholarly journals Involvement of serotonergic system in motion sickness of Suncus murinus.

1994 ◽  
Vol 64 ◽  
pp. 201
Author(s):  
Fumihiko Okada ◽  
Hiroshi Saito ◽  
Norio Matsuki
Keyword(s):  
Motion Sickness ◽  
Serotonergic System ◽  
Suncus Murinus

The role of tryptophan in hepatic encephalopathy

1993 ◽  
Vol 5 (4) ◽  
pp. 71-75
Author(s):  
C. Aaldijk ◽  
W.W. Van Den Broek ◽  
R.C. Van Der Mast
Keyword(s):  
Hepatic Encephalopathy ◽  
Clinical Picture ◽  
Serotonergic System ◽  
Pathogenetic Mechanisms ◽  
Research Findings ◽  
Glutamine Synthesis ◽  
The Brain ◽  
Tryptophan Uptake

SummaryIn this review the most important hypotheses for the occurrence of the clinical picture of hepatic encephalopathy are discussed. As possible pathogenetic mechanisms are raised: dysfunction of the serotonergic system due to an increased tryptophan uptake in the brain, an elevated intracerebral ammoniac concentration and glutamine synthesis, and a heightened intracerebral GABA-activity.The dysregulation of the serotonergic system as a consequence of the increased intracerebral tryptophan uptake is described as one of the most important pathogenetic mechanisms. The elevated intracerebral ammoniac concentration and the elevated intracerebral glutamine synthesis play in this a facilitating role. The similarity in symptomatology of the clinical picture of HE and the serotonergic syndrome support this hypothesis. Due to contradictory research findings the role of the GABA-ergic system and the occurrence of HE remains unclear.

Pre- and postnatal lead exposure affects the serotonergic system in the immature rat brain

1991 ◽  
Vol 47 (5) ◽  
pp. 463-466 ◽  
Author(s):  
H. R. Widmer ◽  
E. E. Bütikofer ◽  
M. Schlumpf ◽  
W. Lichtensteiger
Keyword(s):  
Rat Brain ◽  
Lead Exposure ◽  
Serotonergic System ◽  
Immature Rat
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