The impact of environmental enrichment on sex-specific neurochemical circuitries – Effects on brain-derived neurotrophic factor and the serotonergic system

Neuroscience ◽  
2012 ◽  
Vol 220 ◽  
pp. 267-276 ◽  
Author(s):  
S. Chourbaji ◽  
H. Hörtnagl ◽  
R. Molteni ◽  
M.A. Riva ◽  
P. Gass ◽  
...  
2019 ◽  
Vol 49 (10) ◽  
pp. 1529-1546 ◽  
Author(s):  
Nastasia Marinus ◽  
Dominique Hansen ◽  
Peter Feys ◽  
Raf Meesen ◽  
Annick Timmermans ◽  
...  

2006 ◽  
Vol 24 (7) ◽  
pp. 1850-1856 ◽  
Author(s):  
Chiara Rossi ◽  
Andrea Angelucci ◽  
Laura Costantin ◽  
Chiara Braschi ◽  
Mario Mazzantini ◽  
...  

2009 ◽  
Vol 8 (4) ◽  
pp. 499-506 ◽  
Author(s):  
Francesco Angelucci ◽  
Paola De Bartolo ◽  
Francesca Gelfo ◽  
Francesca Foti ◽  
Debora Cutuli ◽  
...  

2010 ◽  
Vol 214 (1) ◽  
pp. 319-328 ◽  
Author(s):  
Bernet M. Elzinga ◽  
Marc L. Molendijk ◽  
Richard C. Oude Voshaar ◽  
Boudewijn A. A. Bus ◽  
Jos Prickaerts ◽  
...  

2020 ◽  
Vol 65 (No. 6) ◽  
pp. 269-279
Author(s):  
B Bayraktar ◽  
E Tekce ◽  
H Kaya ◽  
M Karaalp ◽  
E Turunc

Due to its association with several other stress factors (poultry house gases, inadequate ventilation, heat, cold and poor hygiene), the high stocking density is a major stress factor that adversely affects the health and performance of poultry and the quality of the poultry products. Therefore, this experimental study was aimed at analysing the impact of different doses of dietary tarragon (Artemisia dracunculus) on the serum apelin, plasma brain-derived neurotrophic factor (p-BDNF), and cardiac troponin I (cTnI) concentrations, and the correlation between these indicators in laying hens housed at different stocking densities. The aim of this study is to investigate the effects of adding tarragon in different ratios to laying hen rations in the 2<sup>nd</sup> ovulation period on the cTnI, apelin, and BDNF hormone concentrations and the liver histopathology. The experiment was carried out over a period of eight weeks, with 192 Lohman Brown commercial hybrids at 50 weeks of age. Eight groups (four replicates each), composed of laying hens of equal body weight, which were housed at stocking densities of 580 cm<sup>2</sup>/hen and 810 cm<sup>2</sup>/hen and received 0, 1, 5 and 10 mmol/kg of tarragon (Artemisia dracunculus) in the feed, were established. At the end of the trial, 96 of the housed egg-laying hens (3 birds in each subgroup, a total of 12 birds in each group) were randomly selected and blood samples were taken from the vena subcutanea ulnaris. The samples collected were analysed for the apelin, p-BDNF, and cTnI contents. The analysis results demonstrated that tarragon supplementation had no effect on the serum apelin, p-BDNF and cTnI concentrations (P &gt; 0.05). The Sub-Groups ST1, ST1.2, and ST6 presented with severe hyperaemia of the sinusoidal, portal and acinar blood vessels, whilst the hyperaemia of these blood vessels was moderate in Sub-Group ST12. Apelin, BDNF, and cTnI can act as protective factors against negative consequences of stress (e.g., stocking density or heat stress).


2017 ◽  
Vol 30 (1) ◽  
pp. 125-141 ◽  
Author(s):  
Alexandria Meyer ◽  
Greg Hajcak ◽  
Elizabeth Hayden ◽  
Haroon I. Sheikh ◽  
Shiva M. Singh ◽  
...  

AbstractThe error-related negativity (ERN) is a negative deflection in the event-related potential occurring when individuals make mistakes, and is increased in children with internalizing psychopathology. We recently found that harsh parenting predicts a larger ERN in children, and recent work has suggested that variation in the brain-derived neurotrophic factor (BDNF) gene may moderate the impact of early life adversity. Parents and children completed measures of parenting when children were 3 years old (N = 201); 3 years later, the ERN was measured and diagnostic interviews as well as dimensional symptom measures were completed. We found that harsh parenting predicted an increased ERN only among children with a methionine allele of the BDNF genotype, and evidence of moderated mediation: the ERN mediated the relationship between parenting and internalizing diagnoses and dimensional symptoms only if children had a methionine allele. We tested this model with externalizing disorders, and found that harsh parenting predicted externalizing outcomes, but the ERN did not mediate this association. These findings suggest that harsh parenting predicts both externalizing and internalizing outcomes in children; however, this occurs through different pathways that uniquely implicate error-related brain activity in the development of internalizing disorders.


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