Activation of Phosphoinositide 3-kinase in Response to High Glucose Leads to Regulation of Reactive Oxygen Species-Related Nuclear Factor-κB Activation and Cyclooxygenase-2 Expression in Mesangial Cells

Meei Ling Sheu; Feng Ming Ho; Kuo Fang Chao; Ming Liang Kuo; Shing Hwa Liu

doi:10.1124/mol.66.1.187

Activation of Phosphoinositide 3-kinase in Response to High Glucose Leads to Regulation of Reactive Oxygen Species-Related Nuclear Factor-κB Activation and Cyclooxygenase-2 Expression in Mesangial Cells

Molecular Pharmacology ◽

10.1124/mol.66.1.187 ◽

2004 ◽

Vol 66 (1) ◽

pp. 187-196 ◽

Cited By ~ 48

Author(s):

Meei Ling Sheu ◽

Feng Ming Ho ◽

Kuo Fang Chao ◽

Ming Liang Kuo ◽

Shing Hwa Liu

Keyword(s):

Reactive Oxygen Species ◽

High Glucose ◽

Mesangial Cells ◽

Reactive Oxygen ◽

Nuclear Factor Κb ◽

Cyclooxygenase 2 ◽

Nuclear Factor ◽

Oxygen Species ◽

Phosphoinositide 3 Kinase

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Curcumin attenuates high glucose-induced inflammatory injury through the reactive oxygen species-phosphoinositide 3-kinase/protein kinase B-nuclear factor-κB signaling pathway in rat thoracic aorta endothelial cells

Journal of Diabetes Investigation ◽

10.1111/jdi.12767 ◽

2017 ◽

Vol 9 (4) ◽

pp. 731-740 ◽

Cited By ~ 7

Author(s):

Zhen Zhang ◽

Keming Li

Keyword(s):

Reactive Oxygen Species ◽

Endothelial Cells ◽

Protein Kinase ◽

High Glucose ◽

Protein Kinase B ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Oxygen Species ◽

Rat Thoracic Aorta ◽

Phosphoinositide 3 Kinase

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Simvastatin abolishes nitric oxide‐ and reactive oxygen species‐induced cyclooxygenase‐2 expression by blocking the nuclear factor κB pathway in rabbit articular chondrocytes

Cell Biology International ◽

10.1002/cbin.11424 ◽

2020 ◽

Vol 44 (10) ◽

pp. 2153-2162

Author(s):

Seon‐Mi Yu ◽

Yohan Han ◽

Song Ja Kim

Keyword(s):

Nitric Oxide ◽

Reactive Oxygen Species ◽

Articular Chondrocytes ◽

Reactive Oxygen ◽

Nuclear Factor Κb ◽

Cyclooxygenase 2 ◽

Nuclear Factor ◽

Oxygen Species ◽

Rabbit Articular Chondrocytes

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Thioredoxin-interacting Protein Mediates High Glucose-induced Reactive Oxygen Species Generation by Mitochondria and the NADPH Oxidase, Nox4, in Mesangial Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m112.419101 ◽

2013 ◽

Vol 288 (10) ◽

pp. 6835-6848 ◽

Cited By ~ 95

Author(s):

Anu Shah ◽

Ling Xia ◽

Howard Goldberg ◽

Ken W. Lee ◽

Susan E. Quaggin ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Nadph Oxidase ◽

High Glucose ◽

Mesangial Cells ◽

Reactive Oxygen Species Generation ◽

Reactive Oxygen ◽

Oxygen Species ◽

Interacting Protein ◽

Thioredoxin Interacting Protein

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Reactive Oxygen Species by Isoflurane Mediates Inhibition of Nuclear Factor κB Activation in Lipopolysaccharide-Induced Acute Inflammation of the Lung

Anesthesia & Analgesia ◽

10.1213/ane.0b013e31827aec06 ◽

2013 ◽

Vol 116 (2) ◽

pp. 327-335 ◽

Cited By ~ 30

Author(s):

In Sun Chung ◽

Jie Ae Kim ◽

Ju A. Kim ◽

Hyun Sung Choi ◽

Jeong Jin Lee ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Acute Inflammation ◽

Reactive Oxygen ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Oxygen Species

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Dipyridamole inhibits lipopolysaccharide-induced cyclooxygenase-2 and monocyte chemoattractant protein-1 via heme oxygenase-1-mediated reactive oxygen species reduction in rat mesangial cells

European Journal of Pharmacology ◽

10.1016/j.ejphar.2010.09.058 ◽

2011 ◽

Vol 650 (1) ◽

pp. 445-450 ◽

Cited By ~ 8

Author(s):

Yen-Cheng Chen ◽

Cheng-Hsien Chen ◽

Wen-Sheng Ko ◽

Chung-Yi Cheng ◽

Yuh-Mou Sue ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Heme Oxygenase ◽

Mesangial Cells ◽

Reactive Oxygen ◽

Cyclooxygenase 2 ◽

Heme Oxygenase 1 ◽

Oxygen Species ◽

Monocyte Chemoattractant Protein 1 ◽

Monocyte Chemoattractant ◽

Monocyte Chemoattractant Protein

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Fluoxetine Induces Apoptosis in Ovarian Carcinoma Cell Line OVCAR-3 Through Reactive Oxygen Species-Dependent Activation of Nuclear Factor-κB

Basic & Clinical Pharmacology & Toxicology ◽

10.1111/j.1742-7843.2009.00509.x ◽

2009 ◽

Vol 106 (6) ◽

pp. 446-453 ◽

Cited By ~ 37

Author(s):

Chung Soo Lee ◽

Yun Jeong Kim ◽

Eun Ra Jang ◽

Wonyong Kim ◽

Soon Chul Myung

Keyword(s):

Reactive Oxygen Species ◽

Ovarian Carcinoma ◽

Cell Line ◽

Carcinoma Cell ◽

Reactive Oxygen ◽

Nuclear Factor Κb ◽

Carcinoma Cell Line ◽

Nuclear Factor ◽

Oxygen Species ◽

Ovarian Carcinoma Cell Line

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Pranlukast Attenuates Ischemia-like Injury in Endothelial Cells Via Inhibiting Reactive Oxygen Species Production and Nuclear Factor-κB Activation

Journal of Cardiovascular Pharmacology ◽

10.1097/fjc.0b013e318196736c ◽

2009 ◽

Vol 53 (1) ◽

pp. 77-85 ◽

Cited By ~ 14

Author(s):

San-Hua Fang ◽

Yu-Mei Yuan ◽

Fang Peng ◽

Cheng-Tan Li ◽

Li-Hui Zhang ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Endothelial Cells ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Oxygen Species ◽

Species Production

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Adenosine 5′-triphosphate stimulates the increase of TGF-β1 in rat mesangial cells under high-glucose conditions via reactive oxygen species and ERK1/2

Acta Pharmacologica Sinica ◽

10.1038/aps.2009.155 ◽

2009 ◽

Vol 30 (12) ◽

pp. 1601-1606 ◽

Cited By ~ 5

Author(s):

Lin-ping Qu ◽

Hong Xue ◽

Ping Yuan ◽

Li Zhou ◽

Tai Yao ◽

...

Keyword(s):

Reactive Oxygen Species ◽

High Glucose ◽

Mesangial Cells ◽

Reactive Oxygen ◽

Oxygen Species ◽

Tgf Β1

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The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2

Antioxidants and Redox Signaling ◽

10.1089/ars.2016.6800 ◽

2017 ◽

Vol 27 (8) ◽

pp. 453-471 ◽

Cited By ~ 44

Author(s):

Michela Campolo ◽

Giovanna Casili ◽

Flavia Biundo ◽

Rosalia Crupi ◽

Marika Cordaro ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Transcription Factor ◽

Mouse Model ◽

Neuroprotective Effect ◽

Reactive Oxygen ◽

Dimethyl Fumarate ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Oxygen Species ◽

Nuclear Transcription Factor

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Alteration of subcellular redox equilibrium and the consequent oxidative modification of nuclear factor κB are critical for anticancer cytotoxicity by emodin, a reactive oxygen species-producing agent

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2006.02.016 ◽

2006 ◽

Vol 40 (12) ◽

pp. 2183-2197 ◽

Cited By ~ 41

Author(s):

Yawu Jing ◽

Jie Yang ◽

Yumei Wang ◽

Hui Li ◽

Yuying Chen ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Reactive Oxygen ◽

Nuclear Factor Κb ◽

Oxidative Modification ◽

Nuclear Factor ◽

Oxygen Species ◽

Redox Equilibrium

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