scholarly journals Light-driven fine chemical production in yeast biohybrids

Science ◽  
2018 ◽  
Vol 362 (6416) ◽  
pp. 813-816 ◽  
Author(s):  
Junling Guo ◽  
Miguel Suástegui ◽  
Kelsey K. Sakimoto ◽  
Vanessa M. Moody ◽  
Gao Xiao ◽  
...  
Keyword(s):  
Energy Efficient ◽  
Rational Design ◽  
Light Harvesting ◽  
Shikimic Acid ◽  
Genetically Engineered ◽  
Efficient Production ◽  
Chemical Production ◽  
Photogenerated Electrons ◽  
Common Precursor ◽  
Hybrid Platform

Inorganic-biological hybrid systems have potential to be sustainable, efficient, and versatile chemical synthesis platforms by integrating the light-harvesting properties of semiconductors with the synthetic potential of biological cells. We have developed a modular bioinorganic hybrid platform that consists of highly efficient light-harvesting indium phosphide nanoparticles and genetically engineered Saccharomyces cerevisiae, a workhorse microorganism in biomanufacturing. The yeast harvests photogenerated electrons from the illuminated nanoparticles and uses them for the cytosolic regeneration of redox cofactors. This process enables the decoupling of biosynthesis and cofactor regeneration, facilitating a carbon- and energy-efficient production of the metabolite shikimic acid, a common precursor for several drugs and fine chemicals. Our work provides a platform for the rational design of biohybrids for efficient biomanufacturing processes with higher complexity and functionality.

Rational design of a pyrene based luminescent porous supramolecular framework: excimer emission and energy transfer

RSC Advances ◽  
2015 ◽  
Vol 5 (92) ◽  
pp. 74986-74993 ◽  
Author(s):  
Komal Prasad ◽  
Ritesh Haldar ◽  
Tapas Kumar Maji
Keyword(s):  
Energy Transfer ◽  
Rational Design ◽  
Light Harvesting ◽  
Supramolecular Framework ◽  
Excimer Emission ◽  
Design And Synthesis ◽  
Porous Framework ◽  
Synthesis Approach

Based on rational design and synthesis approach, a pyrene based supramolecular flexible porous framework of Zn(ii) has been synthesized. It shows excimer emission and has been exploited for light harvesting application.

scholarly journals Energy-Efficient Production of Cassava-Based Bio-Ethanol

2014 ◽  
Vol 05 (12) ◽  
pp. 925-939 ◽  
Author(s):  
Qian Kang ◽  
Lise Appels ◽  
Jan Baeyens ◽  
Raf Dewil ◽  
Tianwei Tan
Keyword(s):  
Energy Efficient ◽  
Efficient Production

Rational Design and Hierarchical Assembly of a Genetically Engineered Resilin–Silk Copolymer Results in Stiff Hydrogels

2017 ◽  
Vol 3 (8) ◽  
pp. 1576-1585 ◽  
Author(s):  
Sheng-Chen Huang ◽  
Zhi-Gang Qian ◽  
Ao-Huan Dan ◽  
Xiao Hu ◽  
Ming-Liang Zhou ◽  
...  
Keyword(s):  
Rational Design ◽  
Genetically Engineered ◽  
Hierarchical Assembly

Mobile Assistance for Energy-Efficient Production: Scenario Parameters and System Impact

2012 ◽  
pp. 169-184
Author(s):  
Sebastian Schlund ◽  
Stefan Gerlach ◽  
Wolfgang Schweizer ◽  
Uwe Laufs ◽  
Patrick Schneider ◽  
...  
Keyword(s):  
Energy Efficient ◽  
Efficient Production ◽  
System Impact

scholarly journals Genetically Engineered Proteins to Improve Biomass Conversion: New Advances and Challenges for Tailoring Biocatalysts

Molecules ◽  
2019 ◽  
Vol 24 (16) ◽  
pp. 2879 ◽  
Author(s):  
Lucas Ferreira Ribeiro ◽  
Vanesa Amarelle ◽  
Luana de Fátima Alves ◽  
Guilherme Marcelino Viana de Siqueira ◽  
Gabriel Lencioni Lovate ◽  
...  
Keyword(s):  
Protein Engineering ◽  
Rational Design ◽  
Biomass Conversion ◽  
Low Cost ◽  
Catalytic Performance ◽  
Genetically Engineered ◽  
Production Lines ◽  
Current Application ◽  
Powerful Approach

Protein engineering emerged as a powerful approach to generate more robust and efficient biocatalysts for bio-based economy applications, an alternative to ecologically toxic chemistries that rely on petroleum. On the quest for environmentally friendly technologies, sustainable and low-cost resources such as lignocellulosic plant-derived biomass are being used for the production of biofuels and fine chemicals. Since most of the enzymes used in the biorefinery industry act in suboptimal conditions, modification of their catalytic properties through protein rational design and in vitro evolution techniques allows the improvement of enzymatic parameters such as specificity, activity, efficiency, secretability, and stability, leading to better yields in the production lines. This review focuses on the current application of protein engineering techniques for improving the catalytic performance of enzymes used to break down lignocellulosic polymers. We discuss the use of both classical and modern methods reported in the literature in the last five years that allowed the boosting of biocatalysts for biomass degradation.

Green, energy-efficient preparation of CDs-embedded BiPO4 heterostructure for better light harvesting and conversion

2020 ◽  
Vol 391 ◽  
pp. 123551 ◽  
Author(s):  
Qing Chang ◽  
Wenliang Yang ◽  
Fu Li ◽  
Chaorui Xue ◽  
Huiqi Wang ◽  
...  
Keyword(s):  
Energy Efficient ◽  
Light Harvesting ◽  
Green Energy

scholarly journals Is density functional theory accurate for lytic polysaccharide monooxygenase enzymes?

2020 ◽  
Vol 49 (5) ◽  
pp. 1501-1512 ◽  
Author(s):  
Ernst D. Larsson ◽  
Geng Dong ◽  
Valera Veryazov ◽  
Ulf Ryde ◽  
Erik D. Hedegård
Keyword(s):  
Density Functional Theory ◽  
Energy Efficient ◽  
Density Functional ◽  
Efficient Production ◽  
Lytic Polysaccharide Monooxygenase ◽  
Functional Theory ◽  
Polysaccharide Monooxygenase

The lytic polysaccharide monooxygenase (LPMO) enzymes boost polysaccharide depolymerization through oxidative chemistry, which has fueled the hope for more energy-efficient production of biofuel.

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