Atypical is the new norm, for B cells and the rest of us

2021 ◽  
Vol 6 (58) ◽  
pp. eabi7304
Author(s):  
Adam Williams ◽  
Stephanie C. Eisenbarth
Keyword(s):  
Steady State ◽  
B Cells ◽  
Unusual Form ◽  
Activated B Cells

An unusual form of activated B cells in adults is described, called atypical B cells, both in the steady state and after vaccination.

scholarly journals Generation of Human CD40-activated B cells

10.3791/1373 ◽  
2009 ◽  
Author(s):  
Tanja M. Liebig ◽  
Anne Fiedler ◽  
Shahram Zoghi ◽  
Alexander Shimabukuro-Vornhagen ◽  
Michael S. von Bergwelt-Baildon
Keyword(s):  
B Cells ◽  
Activated B Cells

scholarly journals Refining the Neuberger model: Uracil processing by activated B cells

2014 ◽  
Vol 44 (7) ◽  
pp. 1913-1916 ◽  
Author(s):  
Robert W. Maul ◽  
Patricia J. Gearhart
Keyword(s):  
B Cells ◽  
Activated B Cells

scholarly journals Robust T-cell stimulation by Epstein-Barr virus–transformed B cells after antigen targeting to DEC-205

Blood ◽  
2013 ◽  
Vol 121 (9) ◽  
pp. 1584-1594 ◽  
Author(s):  
Carol S. Leung ◽  
Michael A. Maurer ◽  
Sonja Meixlsperger ◽  
Anne Lippmann ◽  
Cheolho Cheong ◽  
...  
Keyword(s):  
T Cell ◽  
B Cells ◽  
Epstein Barr Virus ◽  
Cell Stimulation ◽  
Barr Virus ◽  
T Cell Stimulation ◽  
Key Points ◽  
Epstein Barr ◽  
Mhc Presentation ◽  
Activated B Cells

Key Points B cells contribute to MHC presentation of DEC-205–targeted antigen. Activated B cells present DEC-205–targeted antigen efficiently, because they retain it longer.

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