Concentrations of Tenofovir and Emtricitabine in Breast Milk of HIV-1-Infected Women in Abidjan, Côte d'Ivoire, in the ANRS 12109 TEmAA Study, Step 2
2010 ◽
Vol 55
(3)
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pp. 1315-1317
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ABSTRACTThe aim was to evaluate emtricitabine (FTC) and tenofovir (TFV) neonatal ingestion through breast milk. Median TFV and FTC breast milk doses represented 0.03% and 2%, respectively, of the proposed oral infant doses. Neonatal simulated plasma concentrations were extremely low for TFV but between the half-maximal inhibitory concentration and the adult minimal expected concentration for FTC. The rare children who will acquire HIV despite TDF-FTC therapy will need to be monitored for viral resistance acquisition.
2000 ◽
Vol 23
(5)
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pp. 430-436
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2008 ◽
Vol 55
(3)
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pp. 170-176
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1994 ◽
Vol 48
(1)
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pp. 23-30
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2007 ◽
Vol 23
(9)
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pp. 1155-1160
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2006 ◽
Vol 37
(3)
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pp. 199-205
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2009 ◽
Vol 2
(5)
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pp. 456-463
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