Synergy Testing of Vancomycin-Resistant Enterococcus faecium against Quinupristin-Dalfopristin in Combination with Other Antimicrobial Agents
1999 ◽
Vol 43
(11)
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pp. 2776-2779
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Keyword(s):
ABSTRACT Using checkerboard and time-kill assays, we evaluated the in vitro activity of quinupristin-dalfopristin (RP 59500) alone and in combination with five other antimicrobial agents against 12 clinical strains of vancomycin-resistant Enterococcus faecium(VREF). In time-kill studies, six VREF strains exhibited synergism with the combination of quinupristin-dalfopristin and doxycycline and three exhibited synergism with quinupristin-dalfopristin plus ampicillin-sulbactam. Combinations of quinupristin-dalfopristin with these and other agents warrant further clinical evaluation for the treatment of serious VREF infections.
2008 ◽
Vol 31
(3)
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pp. 296-298
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2007 ◽
Vol 29
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pp. S167-S168
2009 ◽
Vol 65
(2)
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pp. 196-198
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1995 ◽
Vol 22
(4)
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pp. 349-352
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2011 ◽
Vol 41
(8)
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pp. 405-409
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Keyword(s):
Keyword(s):
2007 ◽
Vol 51
(6)
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pp. 2043-2047
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2003 ◽
Vol 47
(12)
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pp. 3760-3763
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