Experimental Prediction of the Evolution of Ceftazidime Resistance in the CTX-M-2 Extended-Spectrum Beta-Lactamase
2005 ◽
Vol 49
(3)
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pp. 1242-1244
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Keyword(s):
ABSTRACT We applied in vitro evolution to an Escherichia coli strain containing bla CTX-M-2 and obtained 10 independent mutant bla CTX-M-2 alleles that confer elevated resistance to ceftazidime (MIC ≥ 32 μg/ml) but lost the ability to confer resistance to cefepime. All alleles had a Pro-to-Ser substitution at position 167.
2012 ◽
Vol 69
(2)
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pp. 67-74
Keyword(s):
2018 ◽
Vol Volume 11
◽
pp. 103-112
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Keyword(s):