The Functional Quality of Soluble Recombinant Polypeptides Produced in Escherichia coli Is Defined by a Wide Conformational Spectrum
2008 ◽
Vol 74
(23)
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pp. 7431-7433
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Keyword(s):
ABSTRACT We have observed that a soluble recombinant green fluorescent protein produced in Escherichia coli occurs in a wide conformational spectrum. This results in differently fluorescent protein fractions in which morphologically diverse soluble aggregates abound. Therefore, the functional quality of soluble versions of aggregation-prone recombinant proteins is defined statistically rather than by the prevalence of a canonical native structure.
2019 ◽
Vol 20
(4)
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pp. 907
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2008 ◽
Vol 61
(2)
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pp. 184-190
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2007 ◽
Vol 76
(1)
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pp. 91-99
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2021 ◽
2009 ◽
Vol 72
(7)
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pp. 1513-1520
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