Role of Tumor Necrosis Factor Alpha in Development of Immunity against Cryptosporidium parvum Infection
Keyword(s):
Tnf Α
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ABSTRACT Tumor necrosis factor (TNF-α) significantly reduced Cryptosporidium parvum development in a murine enterocyte cell line, and a key mechanism of action appeared to be inhibition of parasite invasion. However, TNF-α-deficient mice controlled infection as effectively as wild-type mice. This suggests that TNF-α might have only a redundant role for establishing immunity against C. parvum.
2007 ◽
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pp. 1771-1783
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Vol 69
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pp. 6651-6659
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