scholarly journals Serological Detection of Varicella-Zoster Virus-Specific Immunoglobulin G by an Enzyme-Linked Immunosorbent Assay Using Glycoprotein Antigen

2006 ◽  
Vol 44 (9) ◽  
pp. 3094-3097 ◽  
Author(s):  
A. Sauerbrei ◽  
P. Wutzler
1986 ◽  
Vol 7 (2) ◽  
pp. 71-72 ◽  
Author(s):  
Nabil T. Nassar ◽  
Helen C. Tourna

AbstractFollowing an outbreak of varicella, 18% of a group of 174 young female Filipino nurses ranging in age from 20 to 25 years and working at the American University of Beirut Medical Center (AUMC) were found susceptible to the varicella-zoster virus; as compared to 3% of a matched group of 133 of their Lebanese colleagues. The level of antibody was determined by the Enzyme Linked Immunosorbent Assay (ELISA). Those susceptible were assigned duties in low-risk areas to varicella-zoster in the hospital.


2007 ◽  
Vol 14 (9) ◽  
pp. 1057-1061 ◽  
Author(s):  
Marjaleena Koskiniemi ◽  
Maija Lappalainen ◽  
D. Scott Schmid ◽  
Elena Rubtcova ◽  
Vladimir N. Loparev

ABSTRACT We evaluated the seroprevalence of varicella-zoster virus (VZV) in the Finnish population among various age groups and genetically characterized VZV strains from documented cases of varicella and zoster. VZV-specific immunoglobulin G was measured in 2,842 serum samples that had been submitted for virological studies to the Department of Virology, University of Helsinki, from 1995 to 1996. Specimens for VZV genotyping were obtained from vesicular lesions from two pediatric patients and 26 adult patients. Seroprevalence to VZV varied markedly by age: 45% in children aged ≤2 months, 12.5% in children aged 6 to 8 months, and >90% in children near 10 years of age, plateauing thereafter into advanced age. The seroprevalence rates indicate that in Finland, as in other countries with temperate climates, primary VZV infection usually occurs during the first decade of life. Twenty-eight VZV DNA-positive specimens were analyzed to identify VZV vaccine and wild-type genotypes. All analyzed specimens were wild type and the European (E) genotype.


Sign in / Sign up

Export Citation Format

Share Document