scholarly journals In Vitro Activity of Ceftolozane-Tazobactam as Determined by Broth Dilution and Agar Diffusion Assays against Recent U.S. Escherichia coli Isolates from 2010 to 2011 Carrying CTX-M-Type Extended-Spectrum  -Lactamases

2014 ◽  
Vol 52 (11) ◽  
pp. 4049-4052 ◽  
Author(s):  
M. Estabrook ◽  
B. Bussell ◽  
S. L. Clugston ◽  
K. Bush
Keyword(s):  
Escherichia Coli ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Agar Diffusion ◽  
Extended Spectrum ◽  
Broth Dilution

In vitro activity of β-lactam and non–β-lactam antibiotics in extended-spectrum β-lactamase–producing clinical isolates of Escherichia coli

2006 ◽  
Vol 54 (2) ◽  
pp. 135-139 ◽  
Author(s):  
Antonio Sorlózano Puerto ◽  
José Gutiérrez Fernández ◽  
Juan de Dios Luna del Castillo ◽  
María José Soto Pino ◽  
Gonzalo Piédrola Angulo
Keyword(s):  
Escherichia Coli ◽  
Vitro Activity ◽  
Clinical Isolates ◽  
In Vitro Activity ◽  
Extended Spectrum

scholarly journals In Vitro Activity of Sulopenem, an Oral Penem, against Urinary Isolates of Escherichia coli

2018 ◽  
Vol 63 (1) ◽  
Author(s):  
James A. Karlowsky ◽  
Heather J. Adam ◽  
Melanie R. Baxter ◽  
Andrew J. Denisuik ◽  
Philippe R. S. Lagacé-Wiens ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Multidrug Resistant ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Broth Microdilution ◽  
Content Type ◽  
Extended Spectrum ◽  
Urinary Isolates

ABSTRACT The in vitro activity of sulopenem was assessed against a collection from 2014 to 2016 of 539 urinary isolates of Escherichia coli from Canadian patients by using CLSI-defined broth microdilution methodology. A concentration of sulopenem 0.03 µg/ml inhibited both 50% (MIC50) and 90% (MIC90) of isolates tested; sulopenem MICs ranged from 0.015 to 0.25 µg/ml. The in vitro activity of sulopenem was unaffected by nonsusceptibility to trimethoprim-sulfamethoxazole and/or ciprofloxacin, multidrug-resistant phenotypes, extended-spectrum β-lactamases, or AmpC β-lactamases.

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