scholarly journals Detection of Herpes Simplex Virus Type 2-Specific Immunoglobulin G Antibodies in African Sera by Using Recombinant gG2, Western Blotting, and gG2 Inhibition

2002 ◽  
Vol 40 (10) ◽  
pp. 3635-3640 ◽  
Author(s):  
W. Hogrefe ◽  
X. Su ◽  
J. Song ◽  
R. Ashley ◽  
L. Kong
2007 ◽  
Vol 15 (2) ◽  
pp. 382-384 ◽  
Author(s):  
Thoai D. Ngo ◽  
Oliver Laeyendecker ◽  
Hanh La ◽  
Wayne Hogrefe ◽  
Rhoda Ashley Morrow ◽  
...  

ABSTRACT Sera from 1,238 Vietnamese women in Hanoi were tested for herpes simplex virus type 2 (HSV-2). HSV-2 prevalence was 2.0%. The Kalon and Biokit assays showed significantly higher concordance to Western blotting data than did the Focus assay (P < 0.01). Screening by Focus and then retesting with Kalon/Biokit of positive samples can reduce falsely positive results significantly (P < 0.01).


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