scholarly journals Progesterone-Mediated Enhancement of Hepatitis E Virus Replication in Human Liver Cells

mBio ◽  
2021 ◽  
Author(s):  
Harini Sooryanarain ◽  
S. Ansar Ahmed ◽  
Xiang-Jin Meng
Keyword(s):  
Mortality Rate ◽  
Pregnant Women ◽  
Virus Replication ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Human Liver ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Severe Form ◽  
Human Liver Cells

Hepatitis E is usually a self-limiting acute disease; however, during pregnancy, a severe form of fulminant hepatic failure and high mortality rate are associated with hepatitis E virus (HEV) infection. Increased levels of progesterone and HEV RNA are observed in pregnant women with fulminant hepatic failures.

Fulminant hepatic failure due to hepatitis E virus

1994 ◽  
Vol 21 (6) ◽  
pp. 1156-1157
Author(s):  
Rakesh Aggarwal ◽  
Hansa Shahi ◽  
Sita Naik ◽  
Subhash R. Naik ◽  
Soniya Nityanand ◽  
...  
Keyword(s):  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Hepatitis E Virus ◽  
Hepatitis E

P.332 Detection and characterization of hepatitis E virus RNA in three fulminant hepatic failure cases in children in Argentina

2006 ◽  
Vol 36 ◽  
pp. S163
Author(s):  
M.S. Munne ◽  
S. Vladimirsky ◽  
L. Otegui ◽  
L. Brajterman ◽  
R. Castro ◽  
...  
Keyword(s):  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Virus Rna

Hepatitis E virus infection and fulminant hepatic failure during pregnancy

2007 ◽  
Vol 22 (5) ◽  
pp. 676-682 ◽  
Author(s):  
Nishat Jilani ◽  
Bhudev C Das ◽  
Syed A Husain ◽  
Usha K Baweja ◽  
Debashish Chattopadhya ◽  
...  
Keyword(s):  
Virus Infection ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Hepatitis E Virus ◽  
Hepatitis E

scholarly journals Biochemical Evaluation and Out Come of Hepatitis E in Pregnancy

2015 ◽  
Vol 2 (2) ◽  
pp. 65-67
Author(s):  
Fazle Rabbi Mohammed ◽  
Raihana Amin ◽  
HAM Nazmul Ahasan ◽  
Md Billal Alam
Keyword(s):  
Pregnant Women ◽  
Hepatic Failure ◽  
Hepatitis E Virus ◽  
Serological Test ◽  
Acute Hepatic Failure ◽  
Hepatitis E ◽  
Mean Value ◽  
College Hospital ◽  
Biochemical Evaluation ◽  
In Pregnancy

Background: Viral hepatitis is common in Bangladesh. Hepatitis E virus is waterborne and usually self-limiting. But infection with Hepatitis E virus is a serious threat to pregnancy. In this study, we aimed to assess the clinical course and biochemical evaluation of hepatitis E during pregnancy.Materials & Methods: This descriptive observational study included 50 pregnant women having hepatitis E conducted from September, 2008 to September, 2011 in Dhaka Medical College Hospital. Every case was initially evaluated on the basis of history, clinical examination, liver function profile and serological test of hepatitis E.Result: Anti HEV IgM was detected in each case. Most of them (64%) were in third trimester and only 42% cases got boiled water. The mean value of serum bilirubin, alanine aminotransferase (ALT) and prothrombin time (PT) was 11.62 mg/dl ± 8.01 SD, 777.75 U/L ± 590.39 SD and 29.88 sec ± 12.54 SD respectively. Acute hepatic failure (AHF) was detected in 56% pregnant women. In this study, the death rate of Hepatitis E in pregnancy was 43%.Conclusion: During pregnancy, hepatitis E is associated with the development of acute hepatic failure (AHF) which has high mortality rate.Bangladesh Crit Care J September 2014; 2 (2): 65-67

A case of fulminant hepatic failure caused by hepatitis E virus

2008 ◽  
Vol 1 (2) ◽  
pp. 69-74 ◽  
Author(s):  
Masataka Tsuge ◽  
Chiemi Noguchi ◽  
Nobuhiko Hiraga ◽  
Nami Mori ◽  
Akira Hiramatsu ◽  
...  
Keyword(s):  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Hepatitis E Virus ◽  
Hepatitis E

scholarly journals The Prognosis of Fulminant Hepatic Failure in Pregnant Women due to Hepatitis E

2013 ◽  
Vol 3 (2) ◽  
pp. 94-96
Author(s):  
Disha Sahijwani ◽  
Ajesh Desai ◽  
Hina Oza ◽  
Vijay Kansara ◽  
Pallavi Ninama
Keyword(s):  
Pregnant Women ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Hepatitis E

Retransplant Due to Fulminant Hepatic Failure From Hepatitis E Virus: A Case Report

2018 ◽  
Vol 50 (2) ◽  
pp. 685-686 ◽  
Author(s):  
E. Tenorio González ◽  
M. Robles Díaz ◽  
R. Sanjuan Jiménez ◽  
R. González Grande ◽  
R.V. Olmedo Martín ◽  
...  
Keyword(s):  
Case Report ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Hepatitis E Virus ◽  
Hepatitis E

scholarly journals Study of acute viral hepatitis with special reference to fulminant hepatic failure

2018 ◽  
Vol 5 (4) ◽  
pp. 1533
Author(s):  
Rajesh N. Pankhaniya ◽  
Yogesh N. Parikh ◽  
Dhanya Soodhana Mohan
Keyword(s):  
Hepatic Encephalopathy ◽  
Viral Hepatitis ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Hepatitis E Virus ◽  
Hepatitis A ◽  
Acute Viral Hepatitis ◽  
Hepatitis A Virus ◽  
Hepatitis E ◽  
Age Group

Background: Fulminant hepatic failure is a complication of viral hepatitis and is one of the leading causes of death in hospitalized children with viral hepatitis in India.Methods: All the patients suspected to have acute viral hepatitis and/or fulminant hepatic failures with hepatic encephalopathies were included in the study and the diagnosis was made on the basis of history, clinical examination including a detailed neurological examination. Triage scoring, Glasgow coma scale, encephalopathy grading were recorded at the time of admission and necessary investigations were carried out.Results: The occurrence of acute viral hepatitis and fulminant hepatic failure was 200 (2.004%) and 40 (0.401%) respectively during study period. Highest occurrence of 35.50% in the age group of 4-6 years, yellowish discoloration of the eyes or the urine was the most common presenting complaint. Only 45 % of the children who had fulminant hepatic failure survived and mortality was found to be 100% in those children who had grade 4 hepatic encephalopathy. Mortality was higher in those children who had duration of more than 10 days between the onset of jaundice and encephalopathy. Mortality was higher in those with prothrombin time between 41 to 50 seconds and with serum ammonia level more than 200 mmol/l.  Hepatitis A virus was the most common cause of fulminant hepatic failure and Hepatitis E virus with hepatic encephalopathy was associated with 100 % mortality.Conclusions: Hepatitis A infection though associated with a good prognosis, younger age group (< 6 years) and co infection with Hepatitis E virus have a poor prognosis. Good hygiene practices and early immunization could be a step towards the prevention of Hepatitis A infection.

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