Blockage of tropoelastin secretion by monensin represses tropoelastin synthesis at a pretranslational level in rat smooth muscle cells.
1985 ◽
Vol 5
(1)
◽
pp. 253-258
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Keyword(s):
The blockage of protein secretion in the R22 cultured rat aortic smooth muscle cell strain with monensin repressed tropoelastin gene expression at the mRNA level by ca. 50-fold as measured by biosynthetic pulse-labeling, in vitro translation, and hybridization with a tropoelastin genomic DNA probe. These results suggest that tropoelastin gene expression is autoregulated, and they represent the first reported effect of monensin on gene expression.
Keyword(s):
1992 ◽
Vol 20
(8-9)
◽
pp. 703-707
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1987 ◽
Vol 7
(6)
◽
pp. 593-598
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Keyword(s):
2014 ◽
Vol 8
(5)
◽
pp. 1545-1550
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Keyword(s):
1995 ◽
Vol 22
(9-10)
◽
pp. 749-753
1990 ◽
Vol 189
(1)
◽
pp. 23-29
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