scholarly journals Meconium Microbiome of Very Preterm Infants across Germany

mSphere ◽  
2022 ◽  
Author(s):  
Jonas Klopp ◽  
Pamela Ferretti ◽  
Claudius U. Meyer ◽  
Katja Hilbert ◽  
Annette Haiß ◽  
...  

Meconium is present in the intestines of infants before and after birth and constitutes their first bowel movements postnatally. The consistency, composition and microbial load of meconium is largely different from infant and adult stool.

2020 ◽  
Vol 179 (6) ◽  
pp. 929-937 ◽  
Author(s):  
Renée Lampe ◽  
Esther Rieger-Fackeldey ◽  
Irina Sidorenko ◽  
Varvara Turova ◽  
Nikolai Botkin ◽  
...  

2017 ◽  
Vol 34 (14) ◽  
pp. 1396-1404
Author(s):  
Bruno Piedboeuf ◽  
Robert Platt ◽  
Keith Barrington ◽  
Victoria Bizgu ◽  
Prakesh Shah ◽  
...  

Objective To assess the association of the 2011 Quebec provincial resident duty hour reform, which reduced the maximum consecutive hours worked by all residents from 24 to 16 hours, with neonatal outcomes. Study Design Retrospective observational study of 4,271 infants born between 23 and 32 weeks, admitted at five Quebec neonatal intensive care units (NICUs) participating in the Canadian Neonatal Network (CNN) between 2008 and 2015 was conducted. Adjusted odds ratios (AORs) were calculated to compare mortality and the composite outcome of mortality or major morbidity before and after the implementation of the duty hour reform. Results The mortality rate was 8.4% (218/2,598) before the resident duty hour reform and 8.6% (182/2,123) after the reform (odds ratio [OR] = 1.02, 95% confidence interval [CI] = 0.83–1.26). The composite outcome rate was 32% (830/2,598) before the duty hour reform and 29% (615/2,123) after the reform (OR = 0.87, 95% CI = 0.77–0.98). In the adjusted analyses, the resident call-hour reform was not associated with a significant change in mortality (AOR = 1.17, 95% CI = 0.91–1.50) or composite outcome (AOR = 0.87, 95% CI = 0.74–1.03). Conclusion Reducing residents' duty hours from 24 to 16 hours in Quebec was not associated with a difference in mortality or the composite outcome of very preterm infants.


2014 ◽  
Vol 47 (7-8) ◽  
pp. 584-587 ◽  
Author(s):  
Sergio Verd ◽  
MaríaJosé García ◽  
Antonio Gutiérrez ◽  
Eli Moliner ◽  
Esther López ◽  
...  

Children ◽  
2021 ◽  
Vol 8 (12) ◽  
pp. 1081
Author(s):  
Audrey Marchal ◽  
Meggane Melchior ◽  
André Dufour ◽  
Pierrick Poisbeau ◽  
Claire Zores ◽  
...  

Noise and high light illumination in the neonatal intensive care unit (NICU) are recognized as stressors that could alter the well-being and development of vulnerable preterm infants. This prospective observational study evaluated the pain behaviours of very preterm infants (VPIs) to sound peaks (SPs) and light levels variations (LLVs) in the NICU. We measured spontaneously occurring SPs and LLVs in the incubators of 26 VPIs over 10 h. Their behavioural responses were analysed through video recordings using the “Douleur Aigue du Nouveau-né” (DAN) scale. We compared the maximum DAN scores before and after environmental stimuli and the percentage of VPIs with a score ≥ 3 according to the type of stimuli. A total of 591 SPs and 278 LLVs were analysed. SPs of 5 to 15 dBA and LLVs significantly increased the maximum DAN scores compared to baseline. The occurrence of DAN scores ≥ 3 increased with both stressors, with a total of 16% of SPs and 8% of LLVs leading to quantifiable pain behaviour. Altogether, this study shows that VPIs are sensitive to SPs and LLVs, with a slighter higher sensitivity to SPs. The mechanisms leading to pain behaviours induced by noise and light changes should be evaluated further in the context of VPIs brain development. Our results provide further arguments to optimize the NICU sensory environment of neonatal units and to adapt it to the expectations and sensory abilities of VPIs.


2003 ◽  
Vol 92 (5) ◽  
pp. 1-1 ◽  
Author(s):  
GMSJ Stoelhorst ◽  
SE Martens ◽  
M Rijken ◽  
van Zwieten PHT ◽  
AH Zwinderman ◽  
...  

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