Effects and molecular mechanisms of the biological action of weak and extremely weak magnetic fields

The magnetic alignment of cellulose nanocrystals (CNC) and lepidocrocite nanorods (LpN), pristine and in hybrid suspensions has been investigated using contrast-matched small-angle neutron scattering (SANS) under in situ magnetic fields (0 – 6.8 T) and polarized optical microscopy. The pristine CNC (diamagnetic) and pristine LpN (paramagnetic) align perpendicular and parallel to the direction of field, respectively. The alignment of both the nanoparticles in their hybrid suspensions depends on the relative amount of the two components (CNC and LpN) and strength of the applied magnetic field. In the presence of 10 wt% LpN and fields < 1.0 T, the CNC align parallel to the field. In the hybrid containing lower amount of LpN (1 wt%), the ordering of CNC is partially frustrated in all range of magnetic field. At the same time, the LpN shows both perpendicular and parallel orientation, in the presence of CNC. This study highlights that the natural perpendicular ordering of CNC can be switched to parallel by weak magnetic fields and the incorporation of paramagnetic nanoparticle as LpN, as well it gives a method to influence the orientation of LpN.<br>

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Dynamical mass generation in QED with weak magnetic fields

10.1063/1.2359274 ◽

2006 ◽

Author(s):

A. Ayala ◽

A. Bashir ◽

A. Raya ◽

E. Rojas

Keyword(s):

Magnetic Fields ◽

Mass Generation ◽

Dynamical Mass ◽

Weak Magnetic Fields ◽

Dynamical Mass Generation

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Sensitivity of PS/CoPd Janus particles to an external magnetic field

RSC Advances ◽

10.1039/d1ra02410h ◽

2021 ◽

Vol 11 (28) ◽

pp. 17051-17057

Author(s):

Anna Eichler-Volf ◽

Yara Alsaadawi ◽

Fernando Vazquez Luna ◽

Qaiser Ali Khan ◽

Simon Stierle ◽

...

Keyword(s):

Magnetic Field ◽

Magnetic Properties ◽

External Magnetic Field ◽

Magnetic Fields ◽

Janus Particles ◽

Weak Magnetic Fields

PS/CoPd Janus particles respond very sensitively to application of low external magnetic fields. Owing to the magnetic properties, the PS/CoPd particles may be used, for example, to sense the presence of weak magnetic fields as micro-magnetometers.

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Mangiferin as New Potential Anti-Cancer Agent and Mangiferin-Integrated Polymer Systems—A Novel Research Direction

Biomolecules ◽

10.3390/biom11010079 ◽

2021 ◽

Vol 11 (1) ◽

pp. 79

Author(s):

Svetlana N. Morozkina ◽

Thi Hong Nhung Vu ◽

Yuliya E. Generalova ◽

Petr P. Snetkov ◽

Mayya V. Uspenskaya

Keyword(s):

Molecular Mechanisms ◽

Biological Activities ◽

Research Direction ◽

Biological Action ◽

The Body ◽

Biologically Active ◽

Polymer Systems ◽

Anti Cancer ◽

Long Time ◽

Cancer Agent

For a long time, the pharmaceutical industry focused on natural biologically active molecules due to their unique properties, availability and significantly less side-effects. Mangiferin is a naturally occurring C-glucosylxantone that has substantial potential for the treatment of various diseases thanks to its numerous biological activities. Many research studies have proven that mangiferin possesses antioxidant, anti-infection, anti-cancer, anti-diabetic, cardiovascular, neuroprotective properties and it also increases immunity. It is especially important that it has no toxicity. However, mangiferin is not being currently applied to clinical use because its oral bioavailability as well as its absorption in the body are too low. To improve the solubility, enhance the biological action and bioavailability, mangiferin integrated polymer systems have been developed. In this paper, we review molecular mechanisms of anti-cancer action as well as a number of designed polymer-mangiferin systems. Taking together, mangiferin is a very promising anti-cancer molecule with excellent properties and the absence of toxicity.

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