Model of the Final Stage of Nonstationary Radiation Swelling of Metals

2020 ◽  
Vol 121 (7) ◽  
pp. 611-617
Author(s):  
A. V. Kozlov ◽  
I. A. Portnykh ◽  
A. R. Isinbaev
Keyword(s):  
Final Stage ◽  
Nonstationary Radiation ◽  
Radiation Swelling

At the final stage of the global crisis: Economic tasksin 2017-2019

2018 ◽  
pp. 5-29 ◽  
Author(s):  
V. A. Mau
Keyword(s):  
Economic Growth ◽  
Final Stage ◽  
Government Regulation ◽  
Inflation Targeting ◽  
Social Dynamics ◽  
Growth Stimulation ◽  
Central Banks ◽  
Economic Area ◽  
National Trends

The paper deals with the global and national trends of economic and social development at the final stage of the global structural crisis. Special attention is paid to intellectual challenges economists will face with in the post-crisis world: prospects of growth without inflation, new global currencies and the role of cryptocurrencies, central banks independence and their role in economic growth stimulation, new tasks and patterns of government regulation, inequality and growth. Special features of Russian post-crisis development are also under consideration. Among them: prospects of macroeconomic support of growth, inflation targeting, new fiscal rule, social dynamics and new challenges to welfare state. The paper concludes that the main obstacles for economic growth in Russia are concentrated in the non-economic area.

Light Dramaturgy as an Element of an Integrated Approach to the Creation of Museum Expositions and Exhibition Projects

2019 ◽  
pp. 108-114
Author(s):  
Nicolay R. Vorobyov
Keyword(s):  
Final Stage ◽  
Historical Development ◽  
Integrated Approach ◽  
Lighting Design ◽  
Lighting System ◽  
Scientific Concepts ◽  
Hands On ◽  
Artistic Styles ◽  
The Creation

Architectural and artistic construction of museum is one of the most complex genres in environment development and design, with its inherent qualities, means of expressiveness, principles of environment and image development, scientific concepts, in the context of historical development, artistic styles and trends. The author of the article considers the artistic lighting design in isolation from the integral dramaturgy of the project to be deeply flawed, and the setting of accent lighting at the final stage Ц to be simple, but not outstanding. Based on extensive hands-on experience in the construction of museum expositions, the author of the article reveals some peculiarities, especially significant to the participants of the lighting system setting for museums and other cultural facilities.

The final stage of granitoid magmatism in the Dniester-Bug megablocks Ukrainian shield

2016 ◽  
Vol 36 ◽  
pp. 72-81 ◽  
Author(s):  
L.M. Stepaniuk ◽  
◽  
T.Y. Dovbush ◽  
S.Y. Kurylo ◽  
Y.M. Lesnaya ◽  
...  
Keyword(s):  
Final Stage ◽  
Ukrainian Shield ◽  
Granitoid Magmatism

TRAINING USE IN PREPARING FUTURE TEACHERS TO BUILD A PROFESSIONAL CAREER

2019 ◽  
pp. 46-54
Author(s):  
Taras Olefirenko
Keyword(s):  
Capacity Building ◽  
Final Stage ◽  
Professional Training ◽  
Group Discussion ◽  
Role Play ◽  
Future Teachers ◽  
Professional Career ◽  
Training Organization

The article presents the experience of using training teaching technologies in the process of future teachers’ professional training. There is considered the specificity of the training organization, which includes all types of training that affect the qualities, skills and abilities that are manifested in the process of communication with students. The main stages of the training are highlighted, which include: the stage of capacity building; the orientation phase, in the form of role play or group discussion; the stage of study and the final stage.

A Novel Scheme for the Synthesis of 21-Acetoxypregna-1,4,9(11)-triene- 17α,21-diol-3,20-dione from 9α-Hydroxyandrostenedione

2020 ◽  
Vol 16 (5) ◽  
pp. 606-610
Author(s):  
Nguyen T. Diep ◽  
Luu D. Huy
Keyword(s):  
Double Bond ◽  
Chemical Synthesis ◽  
Economic Efficiency ◽  
Final Stage ◽  
Side Chain ◽  
Entire Process ◽  
Drug Synthesis ◽  
First Time

Background: Vietnam currently imports up to 90% of the pharmaceuticals it consumes and 100% of the steroid-based pharmaceuticals. The ability for efficient chemical synthesis of the steroids could create commercial opportunities to address this issue. Synthesis of 21-acetoxypregna-1,4,9(11)- triene-17α,21-diol-3,20-dione is considered a key intermediate in the scheme of steroidal drug synthesis. Previous synthesis attempts of such steroids (corticoids) introduce a double bond at C-1(2) in the final stage of synthesis, which delivers a poor yield and reduces the economic efficiency of the process. Objective: To study and develop a novel and effective method for the synthesis of 21-acetoxypregna- 1,4,9(11)-triene-17α,21-diol-3,20-dione. Methods: Using 9α-hydroxyandrostenedione as a substrate chemical synthesis was performed as follows: pregnane side chain construction at C-17 (acetylene method), introduction of C-1(2) double bond (using SeO2), epimerization of C-17 (via 17-ONO2 ester) and Stork’s iodination. Results: 21-acetoxypregna-1,4,9(11)-triene-17α,21-diol-3,20-dione was prepared from 9α- hydroxyandrostenedione with an improved yield compared to previous attempts. Conclusion: Here, 21-acetoxypregna-1,4,9(11)-triene-17α,21-diol-3,20-dione has been synthesized from 9α-hydroxyandrostenedione based on a novel, effective and commercially feasible scheme. The introduction of the C-1(2) double bond at an earlier stage of the synthesis has increased the economic efficiency of the entire process. For the first time, the indirect epimerization mechanism has been clarified along with the configuration of the C-17 stereo-center which has been confirmed using NOESY data.

Transitional Figures: Immanuel Kant, Adam Smith, James Madison

2018 ◽  
Author(s):  
Nicholas Greenwood Onuf
Keyword(s):  
Civil Society ◽  
Immanuel Kant ◽  
Final Stage ◽  
Adam Smith ◽  
Animal Husbandry ◽  
Legal Order ◽  
Human History ◽  
James Madison ◽  
Human Reason ◽  
Mutual Exchange

Foucault’s sense of the modern epoch finds Kant everywhere in the background. If, for Kant, nature appears to accommodate our needs, human reason nevertheless has a purpose beyond ourselves; nature’s purpose dictates our use of reason. Kant had us use reason to progress from savagery to animal husbandry and the cultivation of the land, mutual exchange, culture, and civil society. Better known are Smith’s four stages of human history: the Ages of Hunters, Shepherds, Agriculture, and Commerce. Set back by nomadic barbarians, Europe belatedly developed a novel society of independent nations, ever vigilant (and often enough at war), committed to improving their productive capabilities and reaping the benefits of commerce. Rationalization and positivism marked the final stage, which in turn required a positive legal order grounded in unimpeachable sources of law. These James Madison definitively articulated when he was U.S. secretary of state.

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