New Methods for the Synthesis of Alkoxy Derivatives of the closo-Decaborate Anion [2-B10H9(OR)]2–, Where R = C2H5, iso-C3H7, С4H9

1,1-Diphenylindan was treated with one molecule of bromine. It yielded a monobromide, which was condensed with methyl and ethyl alcohols, piperidine, p-toluidine, and aniline. With aqueous solutions of potassium carbonate, the monobromide directly gave rise to 1,1-diphenylindene and small quantities of diphenylindanyl ether.The condensation of the monobromide with sodium ethyl malonate yielded ethyl 1,1-diphenyl-3-indanmalonate from which 1,1-diphenyl-3-indanmalonic and 1-1-diphenyl-3-indanacetic acids were prepared. A few derivatives of these acids were also obtained.To establish the constitution of 1,1-diphenyl-3-indanacetic acid and, hence, that of the monobromide and of the other compounds, this acid was prepared directly from 3,3-diphenyl-1-indanone by a Reformatsky reaction with ethyl bromoacetate.The method of preparation of 1,1-diphenylindan has been improved, 1,1-diphenylindene has been obtained by new methods, and the following compounds are described, as far as the authors are aware, for the first time: 3-bromo-1,1-diphenylindan, 3-methoxy-1,1-diphenylindan, 3-ethoxy-1,1-diphenylindan, 3-N-piperidyl-1,1-diphenylindan, N-phenyl-1,1-diphenyl-3-indanamine, N-p-tolyl-1,1-diphenyl-3-indanamine, ethyl 1,1-diphenyl-3-indanmalonate, 1,1-diphenyl-3-indanmalonic acid, 1,1-diphenyl-3-indanmalonic acid p-nitrobenzyl ester, silver salt of 1,1-diphenyl-3-indanmalonic acid, 1,1-diphenyl-3-indanacetic acid, 1,1-diphenyl-3-indanacetic acid p-nitrobenzyl ester, silver salt of 1,1-diphenyl-3-indanacetic acid, 1,1-diphenyl-3-indanacetanilide, 1,1-diphenyl-3-indanacetamide, 1,1-diphenyl-3-indanacetonitrile, 1,1-diphenyl-3-indanethylamine hydrochloride, ethyl 3-hydroxy-1,1-diphenyl-3-indanacetate, ethyl 1,1-diphenyl-3-indeneacetate, 1,1-diphenyl-3-indeneacetic acid, silver salt of 1,1-diphenyl-3-indeneacetic acid, 1,1-diphenyl-3-indeneacetic acid p-nitrobenzyl ester, ethyl 1,1-diphenyl-3-indanacetate.

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Noncovalent interactions in perchlorinated sulfonium and ammonium derivatives of closo-decaborate anion: 35Cl NQR and crystal structure

Polyhedron ◽

10.1016/j.poly.2021.115514 ◽

2021 ◽

pp. 115514

Author(s):

E.A. Kravchenko ◽

A.A. Gippius ◽

S.V. Zhurenko ◽

A.V. Tkachev ◽

V.A. Semenova ◽

...

Keyword(s):

Crystal Structure ◽

Noncovalent Interactions ◽

35Cl Nqr ◽

Closo Decaborate Anion ◽

Derivatives Of

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Recent Synthetic Methodologies for Chalcone Synthesis (2013-2018)

Current Organocatalysis ◽

10.2174/2213337206666190306155140 ◽

2019 ◽

Vol 6 (3) ◽

pp. 184-192 ◽

Cited By ~ 8

Author(s):

Saba Farooq ◽

Zainab Ngaini

Keyword(s):

Carbonyl Compounds ◽

Short Review ◽

High Yield ◽

New Methods ◽

Recent Modification ◽

Synthetic Methodologies ◽

Derivatives Of ◽

Heterocyclic Structure

An up-to-date short review of the chalcone methodologies is presented, which is the most interesting and beneficial for choosing the desired protocol to synthesize suitable derivatives of chalcones. Chalcones are fluorescent, stable compounds which contribute to the synthesis of various pharmacologically important heterocyclic structure-based derivatives. Chalcone has displayed a remarkable curative efficiency to cure several diseases. Several schemes and methodologies have been reported for employing different catalysts and reagents. The development of improved methodologies of α, β-unsaturated carbonyl compounds is still on going. In this review, synthetic methodologies and their recent modification in designing new methods with efficient, economical, eco-friendly and high yield are discussed.

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Nucleophilic addition of amino acid esters to nitrilium derivatives of closo-decaborate anion

Mendeleev Communications ◽

10.1016/j.mencom.2021.03.018 ◽

2021 ◽

Vol 31 (2) ◽

pp. 201-203

Author(s):

Alexey V. Nelyubin ◽

Ilya N. Klyukin ◽

Alexander S. Novikov ◽

Andrey P. Zhdanov ◽

Mikhail S. Grigoriev ◽

...

Keyword(s):

Amino Acid ◽

Nucleophilic Addition ◽

Amino Acid Esters ◽

Closo Decaborate Anion ◽

Derivatives Of ◽

Acid Esters

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THE METHOD FOR OBTAINING A DERIVATIVE CLOSO-DECABORATE ANION WITH PENDANTE DTPA-GROUP

Тонкие химические технологии ◽

10.32362/2410-6593-2019-14-1-59-65 ◽

2019 ◽

Vol 14 (1) ◽

pp. 59-65 ◽

Cited By ~ 1

Author(s):

E. Yu. Matveev ◽

S. S. Akimov ◽

A. S. Kubasov ◽

V. M. Retivov ◽

K. Yu. Zhizhin ◽

...

Keyword(s):

Malignant Tumors ◽

Complexing Agent ◽

Polydentate Ligand ◽

Boron Cluster ◽

Therapeutic Function ◽

Closo Decaborate Anion ◽

Thermographic Analysis ◽

Combined Action ◽

Esi Mass Spectrometry ◽

Derivatives Of

This paper describes the method for obtaining a new derivative of the closo-decaborate anion with diethylenetriaminepentaacetic acid (DTPA) as a pendant group attached to the boron cluster through an alkoxyl spacer chain. This derivative is formed by the interaction of 1,4-dioxane derivative of the anion [B10H10]2- with DTPA potassium salt in an aqueous medium. As a result of the reaction, an exo-polyhedral cyclic substituent is opened, and then the addition of a polyfunctional group through an oxygen atom occurs. The synthesized compound is in fact an effective polydentate ligand capable of coordinating to the complexing agent both due to the donor atoms of the attached DTPA fragment and through the formation of three-center two-electron bonds. The obtained compound interacts with gadolinium(III) carbonate forming a complex of the composition [Gd2B10H9O2C4H8(dtpa)]·3H2O. The synthesized substances were studied by IR spectroscopy, polynuclear (11B, 13C and 1H) NMR spectroscopy, ESI mass spectrometry, elemental and thermographic analysis. closo-Decaborate with the pendant DTPA group is of interest in 10B neutron capture therapy of malignant tumors due to the high content of boron atoms and a convenient way of their transport to the affected cells. The obtained boron-containing derivatives of gadolinium(III) can act as drugs of combined action, because they can perform, in addition to the above described therapeutic function, the diagnostic function due to the presence of gadolinium atoms int hem.

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ChemInform Abstract: New Methods of Synthesis of Boron, Germanium, and Tin Derivatives of Pentavalent Phosphorus Thioacids.

ChemInform ◽

10.1002/chin.200225158 ◽

2010 ◽

Vol 33 (25) ◽

pp. no-no

Author(s):

Il'yas S. Nizamov ◽

Tat'yana P. Sorokina ◽

Il'nar D. Nizamov ◽

Nailya G. Galimullina ◽

Elvira S. Batyeva ◽

...

Keyword(s):

Pentavalent Phosphorus ◽

New Methods ◽

Methods Of Synthesis ◽

Derivatives Of

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Two methods to find analytical redundancy relations for fault diagnosis

at - Automatisierungstechnik ◽

10.1515/auto-2016-0121 ◽

2017 ◽

Vol 65 (4) ◽

Author(s):

Jan Lunze

Keyword(s):

Structural Analysis ◽

Linear System ◽

State Variables ◽

Vector Representation ◽

New Methods ◽

Starting Point ◽

Analytical Redundancy ◽

Matrix Vector ◽

Analytical Expressions ◽

Derivatives Of

AbstractThe paper deals with methods to derive analytical redundancy relations for diagnosable systems. The starting point is an over-determined set of constraints, which is obtained by a structural analysis of the linear system under consideration. The problem is to find analytical expressions for residuals in terms of the measured signals and the derivatives of these signals. Two new methods are described. The first method provides a representation of the residual in terms of the observability matrix of the diagnosable subsystem. The second method replaces the derivative constraints by a series of equations that include the derivatives of the state variables and the outputs. The result is a matrix-vector representation of the over-determined set of equations, which leads to the analytical redundancy relations. The methods are illustrated by their application to an automotive example.

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