Recent Synthetic Methodologies for Chalcone Synthesis (2013-2018)

An up-to-date short review of the chalcone methodologies is presented, which is the most interesting and beneficial for choosing the desired protocol to synthesize suitable derivatives of chalcones. Chalcones are fluorescent, stable compounds which contribute to the synthesis of various pharmacologically important heterocyclic structure-based derivatives. Chalcone has displayed a remarkable curative efficiency to cure several diseases. Several schemes and methodologies have been reported for employing different catalysts and reagents. The development of improved methodologies of α, β-unsaturated carbonyl compounds is still on going. In this review, synthetic methodologies and their recent modification in designing new methods with efficient, economical, eco-friendly and high yield are discussed.

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α-Alkoxyalkyl Triphenylphosphonium Salts: Synthesis and Reactions

Current Organic Chemistry ◽

10.2174/1385272823666190926092242 ◽

2019 ◽

Vol 23 (16) ◽

pp. 1738-1755

Author(s):

Humaira Y. Gondal ◽

Zain M. Cheema ◽

Abdul R. Raza ◽

Ahmed Abbaskhan ◽

M. I. Chaudhary

Keyword(s):

Carbonyl Compounds ◽

Claisen Rearrangement ◽

Alder Reaction ◽

Coupling Reactions ◽

Phosphonium Salts ◽

Organic Transformations ◽

Enol Ethers ◽

Wide Range ◽

Synthetic Methodologies ◽

Alkoxy Groups

Following numerous applications of Wittig reaction now functionalized phosphonium salts are gaining attention due to their characteristic properties and diverse reactivity. This review is focused on α-alkoxyalkyl triphenylphosphonium salts: an important class of functionalized phosphonium salts. Alkoxymethyltriphenylphosphonium salts are majorly employed in the carbon homologation of carbonyl compounds and preparation of enol ethers. Their methylene insertion strategy is extensively demonstrated in the total synthesis of a wide range of natural products and other important organic molecules. Similarly enol ethers prepared thereof are important precursors for different organic transformations like Diels-Alder reaction, Claisen rearrangement, Coupling reactions, Olefin metathesis and Nazarov cyclization. Reactivity of these α-alkoxyalkylphosphonium salts have also been studied in the nucleophilic substitution reactions. A distinctive application of this class of phosphonium salts was recently reported in the phenylation of carbonyl compounds under very mild conditions. Synthesis of structurally diverse alkoxymethyltriphenylphosphonium salts with variation in alkoxy groups as well as counter anions are reported in literature. Here we present a detailed account of different synthetic methodologies for the preparation of this unique class of quaternary phosphonium salts and their applications in organic synthesis.

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Core-Substituted Naphthalene-diimides (cNDI) and Related Derivatives: Versatile Scaffold for Supramolecular Assembly and Functional Materials

Organic Materials ◽

10.1055/a-1530-0476 ◽

2021 ◽

Author(s):

Anurag Mukherjee ◽

Suhrit Ghosh

Keyword(s):

Photophysical Properties ◽

Supramolecular Assembly ◽

Functional Materials ◽

Building Blocks ◽

Short Review ◽

Molecular Engineering ◽

Organic Optoelectronics ◽

Naphthalene Diimide ◽

Naphthalene Diimides ◽

Derivatives Of

Naphthalene-diimide (NDI) derived building blocks have been explored extensively for supramolecular assembly as they exhibit attractive photophysical properties, suitable for applications in organic optoelectronics. Core-substituted derivatives of the NDI chromophore (cNDI) differ significantly from the parent NDI dye in terms of optical and redox properties. Adequate molecular engineering opportunities and substitution-dependent tunable optoelectronic properties make cNDI derivatives highly promising candidates for supramolecular assembly and functional material. This short review discusses recent development in the area of functional supramolecular assemblies based on cNDIs and related molecules.

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Tautomerism and geometric isomerism of nitrogen-containing derivatives of carbonyl compounds

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science ◽

10.1007/bf00911433 ◽

1961 ◽

Vol 10 (10) ◽

pp. 1652-1658 ◽

Cited By ~ 1

Author(s):

Yu. P. Kitaev ◽

G. K. Budnikov ◽

A. E. Arbuzov

Keyword(s):

Carbonyl Compounds ◽

Geometric Isomerism ◽

Derivatives Of

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Cleavage of C=N derivatives and Oxidation of Thiols in Water under Neutral Conditions with 1,4-dichloro-1,4-diazoniabicyclo[2,2,2]octane bischloride

Journal of Chemical Research ◽

10.3184/030823407x240890 ◽

2007 ◽

Vol 2007 (8) ◽

pp. 486-489 ◽

Cited By ~ 4

Author(s):

Mahmood Tajbakhsh ◽

Setareh Habibzadeh

Keyword(s):

Carbonyl Compounds ◽

High Yield ◽

Reaction Conditions ◽

Neutral Conditions

1,4-Diazabicyclo[2,2,2]octane (DABCO) is easily chlorinated and gives a complex which efficiently converts aliphatic and aromatic oximes, phenylhydrazones and semicarbazones to their corresponding carbonyl compounds in water at 50°C in high yield. This reagent can also be used for conversion of thiols to their compounding disulfide under the same reaction conditions. DABCO is quantitatively recovered which can be rechlorinated and reused several times.

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