Simple Preparation of Methyl 4-Chloromethyl- and Methyl 5-Chloromethyl-2-thiophenecarboxylate
1992 ◽
Vol 57
(7)
◽
pp. 1483-1486
◽
Selective reduction of a mixture of methyl 4-chloromethyl-2-thiophenecarboxylate (I) and the 5-chloromethyl isomer II, prepared by chloromethylation of methyl 2-thiophenecarboxylate (III), gave pure 4-chloromethyl derivative I and 5-methyl-2-thiophenecarboxylate (V) which on treatment with sulfuryl chloride was converted into the 5-chloromethyl isomer II.
1964 ◽
Vol 5
(35)
◽
pp. 2423-2426
◽
1992 ◽
pp. 1447-1452
◽
1990 ◽
Vol 48
(3)
◽
pp. 226-227
2002 ◽
Vol 2002
(3)
◽
pp. 110-111
◽
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