scholarly journals OP0257 VALUE OF COLOR DOPPLER ULTRASOUND ASSESSMENT OF SACROILIAC JOINTS IN NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS:A COMPARISON WITH ANKYLOSING SPONDYLITIS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 157.1-157
Author(s):  
N. MA ◽  
S. Haili

Background:Ultrasound (US) is an accessible imaging technique with a possible role to diagnose active sacroiliitis, so this technique is projected as a promising diagnostic tool for the diagnosis of spondyloarthritis(SpA).The diagnostic value of sacroiliac US has been studied in patients with Ankylosing Spondylitis(AS),becoming a useful and practical tool in comparison with MRI.There are scarce data on the utility of US in the evaluation of Non-radiographic Axial Spondyloarthritis (nr-axSpA).Objectives:The aim of this study is to evaluate the diagnostic utility of color Doppler ultrasound (CDUS) for the detection of sacroiliitis in patients with nr-axSpA and AS.Methods:Patients with nr-axSpA (n=114) and AS(n=80) were enrolled in the study with standardized clinical criteria.According to the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI),nr-axSpA and AS patients were separately divided into active group(n=47,n=43)and inactive group (n=67,n=37).All patients underwent clinical evaluation,and CDUS of sacroiliac joints (SIJs) within the same week. Vascularization, the resistive index (RI) of the SIJs and the first foraminal ramus of the lateral sacral artery were observed and measured by a sonographer who is blinded to initial clinical and radiological assessments. The associated statistics and graphs was utilized to obtain the relationship,which were reflected by the Co-index receiver operating characteristic(ROC)curve or calculating the area under ROC curve(AUC),between the RI of the SIJs and the RI of the first foraminal ramus of the lateral sacral artery in nr-axSpA and AS by using the Logistic Regressive analysis methods,SPSS24.0 and MedCalc19.6.0 software.With MRI-proven sacroiliitis as thediagnostic standard,the Kappa test were used to measure the consistency between the RI of the SIJs and MRI.Results:1. The RI of the SIJs(AUC=0.855,P<0.001)and Co-index(AUC=0.886,P<0.001)were similar sufficient (Z=1.331, P=0.183) to distinguish the active and inactive group in nr-axSpA .2.The RI of the SIJs(AUC=0.869,P<0.001)and Co-index(AUC=0.893,P<0.001)were also similar sufficient (Z=1.292, P=0.196) to distinguish the active and inactive group in AS .3.Neither of the RI of the first foraminal ramus of the lateral sacral artery in nr-axSpA(AUC=0.748,P<0.001)and AS(AUC=0.674,P=0.003)was outstanding to distinguish the active and inactive group.4.The RI of the SIJs was similar sufficient (Z=0.267,P=0.790) to detect sacroiliitis in nr-axSpA and AS.5. The Co-index was also similar sufficient (Z=0.146, P=0.884) to detect sacroiliitis in nr-axSpA and AS.6.The RI of the SIJs in nr-axSpA and AS showed moderate consistency with MRI(the Kappa values were 0.534 and 0.609,respectively,P<0.01).Conclusion:The RI of the SIJs is a possible role to diagnose active sacroiliitis, so CDUS is projected as a promising diagnostic tool for the diagnosis of nr-axSpA and AS in comparison with MRI.References:[1]Rosa JE, Ruta S, Bravo M, et al. Value of Color Doppler Ultrasound Assessment of Sacroiliac Joints in Patients with Inflammatory Low Back Pain. J Rheumatol. 2019 Jul;46(7):694-700.Disclosure of Interests:None declared

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1840.2-1840
Author(s):  
M. Bouaziz ◽  
D. Ben Nessib ◽  
H. Riahi ◽  
K. Maatallah ◽  
E. Labbene ◽  
...  

Background:Magnetic resonance imaging (MRI) of sacroiliac joints (SIJ) can assess early inflammatory changes, thus allowing an early diagnosis of spondyloarthritis (SpA). However, its use in clinical practice may be limited by its cost, its duration and its limited availability. In this sense, ultrasound (US) has been suggested as a feasible and easy-to-apply alternative.Objectives:The objective of this study was to evaluate the validity of Color Doppler Ultrasound (CDUS) in early assessment of sacroiliitis, compared to MRI findings as the gold standard.Methods:A cross-sectional prospective monocentric study included patients attending the rheumatology department with suggestive signs of SpA between February 2014 and February 2017. Patients with pelvic radiography showing a confirmed sacroiliitis (grade 3 or 4) were not included. Eligible patients underwent US and MRI of SIJ. US examinations were performed by an experimented musculoskeletal radiologist blinded to MRI results. Vascularization within the SIJs was explored by the presence of a CDUS. When an artery was found, the resistive index (RI) was measured. The values of the RI ranged between 0 and 1. Doppler of each SIJ was considered as positive when RI was <0.75.Results:Forty-three patients were included: 10 men and 33 women, with an average age at inclusion of 40.2 ± 11.1 years [17-59]. The mean duration of symptoms was 46±37.5 months [6.6-180]. A personal history of uveitis was noted in 3 patients and of chronic diarrhea in 3 patients. Morning stiffness was noted in 72% (n=31) of patients. Good response to nonsteroidal anti-inflammatory drugs (NSAIDs) and to physical activity were respectively reported by 41.8% (n=18) and 58% (n=25) of patients. Sacroiliac compression test, distraction provocative test, sacral thrust test, Gaenslen’s test, Faber’s test (Patrick) and Mennel’s test were respectively positive in 39.5%, 32.5%, 48.8%, 23.2%, 32.5%, and 51.2% of the patients. Twenty-seven per cent of the patients were HLA-B27+. The MRI showed a confirmed sacroiliitis in 14 patients. Doppler signal was detected in 44 SIJ of 25 patients, of whom 14 SIJ of 8 patients showed bone marrow edema at MRI (p=0.054). At the joint level, considering MRI-proven sacroiliitis as the diagnostic standard, CDUS had a sensitivity of 70%, a specificity of 54.5%, a positive predictive value of 31.8%, and a negative predictive value of 85.7%. The spectral Doppler RI, averagely estimated at 0.74±0.12 [0.48-0.87], was not associated with the presence of sacroiliitis on MRI (p=0.747).Conclusion:US, an imaging technique increasingly used in the assessment of musculoskeletal diseases, has been suggested to detect active sacroiliitis [1, 2]. Our study revealed that in early SpA, CDUS may be useful to assess active inflammatory changes of SIJ since it had a sensitivity of 70%, despite a relatively reduced specificity. However, RI values, which are expected to be low in patients with active inflammation [3], were unrelated to the presence of sacroiliitis. Future studies on larger numbers of patients might be conducted to complete previous data.References:[1]Mohammadi A, Ghasemi-rad M, Aghdashi M, et al (2013) Evaluation of disease activity in ankylosing spondylitis; diagnostic value of color Doppler ultrasonography. Skeletal Radiol 42:219–224.https://doi.org/10.1007/s00256-012-1412-7[2]Hu Z, Xu M, Wang Q, et al (2015) Colour Doppler ultrasonography can be used to detect the changes of sacroiliitis and peripheral enthesitis in patients with ankylosing spondylitis during adalimumab treatment. Clin Exp Rheumatol 33:844–850[3]Arslan H, Sakarya ME, Adak B, et al (1999) Duplex and color Doppler sonographic findings in active sacroiliitis. AJR Am J Roentgenol 173:677–680.https://doi.org/10.2214/ajr.173.3.10470902Disclosure of Interests:None declared


1998 ◽  
pp. 796-799 ◽  
Author(s):  
REI K. CHIOU ◽  
JOHN M. DONOVAN ◽  
JOSEPH C. ANDERSON ◽  
AURELIO MATAMOROS ◽  
RANDY K. WOBIG ◽  
...  

2007 ◽  
Vol 22 (3) ◽  
pp. 701-705 ◽  
Author(s):  
M. Cimador ◽  
M. R. Di Pace ◽  
M. Castagnetti ◽  
M. Sergio ◽  
P. Catalano ◽  
...  

1998 ◽  
Vol 159 (3) ◽  
pp. 796-799 ◽  
Author(s):  
REI K. CHIOU ◽  
JOHN M. DONOVAN ◽  
JOSEPH C. ANDERSON ◽  
AURELIO MATAMOROS ◽  
RANDY K. WOBIG ◽  
...  

2017 ◽  
Vol 43 (6) ◽  
pp. 817-825 ◽  
Author(s):  
Nelson Lobos ◽  
Ximena Wortsman ◽  
Fernando Valenzuela ◽  
Faustino Alonso

2018 ◽  
Vol 46 (7) ◽  
pp. 694-700 ◽  
Author(s):  
Javier E. Rosa ◽  
Santiago Ruta ◽  
Maximiliano Bravo ◽  
Luciano Pompermayer ◽  
Josefina Marin ◽  
...  

Objective.To evaluate the diagnostic value of color Doppler ultrasound (CDUS) for the detection of sacroiliitis, in patients with inflammatory back pain (IBP).Methods.Consecutive patients with IBP and suspected axial spondyloarthritis (SpA), but without a definitive diagnosis, were included. Consecutive patients with defined SpA and axial involvement were included as a control group. All patients underwent clinical evaluation, magnetic resonance imaging (MRI), and CDUS of sacroiliac joints (SIJ) within the same week. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for the diagnosis of sacroiliitis by CDUS were calculated, using MRI as the gold standard.Results.There were 198 SIJ evaluated in 99 patients (36 with previous SpA). There were 61 men (61.6%), with a mean age of 39.8 years (SD 11.3) and median disease duration of 24 months (IQR 12–84). At the patient level, CDUS had a sensitivity of 63% (95% CI 48.7–75.7%) and a specificity of 89% (95% CI 76–96%). The PPV was 87.2% (95% CI 72.6–95.7%) and the NPV was 66.7% (95% CI 53.3–78.3%). At joint level, CDUS had a sensitivity of 60% (95% CI 49–70%) and a specificity of 93% (95% CI 88–98%). The PPV was 83% (95% CI 78–95%) and the NPV was 43% (95% CI 33–56%). The sensitivity of CDUS for the diagnosis of axial SpA was 54% (95% CI 36.6–71.2%), specificity was 82% (95% CI 63.1–93.9%), PPV was 79% (95% CI 57.8–92.9%), and NPV was 59% (95% CI 42.1–74.4%).Conclusion.CDUS showed adequate diagnostic properties for detection of sacroiliitis and is a useful tool in patients with IBP.


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