Milestone in congenital cardiac surgery: 65 years of the heart–lung machine

2018 ◽  
Vol 105 (1) ◽  
pp. 92-94
Author(s):  
Magdalena Mazurak ◽  
Jacek Kusa



Perfusion ◽  
2005 ◽  
Vol 20 (5) ◽  
pp. 237-241 ◽  
Author(s):  
D Belway ◽  
F D Rubens ◽  
D Wozny ◽  
B Henley ◽  
H J Nathan

Introduction: Despite major advances in biomaterial research and blood conservation, bleeding is still a common complication after cardiopulmonary bypass and cardiac surgery remains a major consumer of blood products. Although the underlying mechanisms for these effects are not fully established, two proposed major etiologies are the hemodilution associated with the use of the heart-lung machine and the impact of reinfusion of shed cardiotomy blood. Therapeutic strategies that primarily encompass the use of devices or technologies to overcome these effects may result in improved clinical outcomes. Objective: To determine the extent to which 1) lipid/leukocyte filtration and centrifugal processing of cardiotomy blood, and 2) modified ultrafiltration (MUF) are currently applied in adult cardiac surgery in Canada. Methods: A questionnaire was mailed to the chief perfusionist at all adult cardiac surgical centers in Canada, addressing details regarding the frequency of use of cardiotomy blood processing and MUF. Results: All questionnaires (36, 100%) were completed and returned. With regards to cardiotomy blood management, in 21 centers (58%), no specific processing steps were utilized exclusive of the integrated cardiotomy reservoir filter. Of the remaining centers, two (6%) reported using lipid/leukocyte filtration and 15 (42%) reported washing their cardiotomy blood. Three centers (8%) reported using MUF at the end of CPB. Conclusions: Despite growing concern about the potential detrimental effects of cardiotomy blood, few centers in Canada routinely manage this blood with additional filtration and/or centrifugal processing prior to reinfusion. Similarly, MUF, demonstrated to be effective in the pediatric population, has not seen popular application in adult cardiac surgical practice.



2016 ◽  
Vol 28 (7) ◽  
pp. 1053-1055 ◽  
Author(s):  
Lisbeth Evered ◽  
Brendan Silbert ◽  
David A. Scott

Changes in cognition are known to follow anesthesia and surgery in older individuals (Evered et al., 2011). Although survival per se was the prime outcome in the 19th and early 20th centuries for invasive procedures, a link was none-the-less observed with adverse cognitive outcomes as far back as 1887 (Savage, 1887). Historical reports of “insanity” or “weak mindedness” after anesthesia appeared within 40 years of the first anesthetic having been administered and anecdotal and retrospective reports have implicated anesthesia ever since. However, it was not until the 1970s that these observations received any sound scientific evaluation, when clinicians became aware of cognitive changes following cardiac surgery. It was assumed that the cardiopulmonary bypass (heart lung machine) must have been the main culprit because it was this factor which so greatly distinguished cardiac surgery from non-cardiac surgery (Shaw et al., 1987). This long held belief entered surgical folklore and was the basis for many publications endeavoring to identify particular aspects of the heart lung machine responsible for this cognitive decline.





Author(s):  
Jeremy W. Cannon ◽  
Robert D. Howe ◽  
Pierre E. Dupont ◽  
John K. Triedman ◽  
Gerald R. Marx ◽  
...  


1956 ◽  
Vol 32 (3) ◽  
pp. 410-416 ◽  
Author(s):  
Jackson H. Stuckey ◽  
Melvin M. Newman ◽  
Clarence Dennis ◽  
Bernard S. Levowitz ◽  
Harry N. Iticovici ◽  
...  


1988 ◽  
Vol 15 (3) ◽  
pp. 713-719 ◽  
Author(s):  
William I. Norwood ◽  
John D. Pigott


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