Refractory primary intestinal lymphangiectasia effectively managed with subcutaneous octreotide

This case report describes a young man with a history of lymphoedema and long-standing gastrointestinal symptoms since childhood. After undergoing extensive investigations, he was diagnosed with primary intestinal lymphangiectasia (IL). The patient’s condition was refractory to conventional medium-chain triglyceride diet but responded well to treatment with subcutaneous octreotide. We have shown octreotide to be effective in improving the pathological effects of primary IL, associated with improved clinical well-being and serology, but it is not a curative therapy.

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Protein-losing enteropathy with systemic lupus erythematosus effectively treated with octreotide and medium chain triglyceride diet: A case report

Japanese Journal of Clinical Immunology ◽

10.2177/jsci.38.421 ◽

2015 ◽

Vol 38 (5) ◽

pp. 421-425 ◽

Cited By ~ 4

Author(s):

Makoto KUBO ◽

Kousuke UCHIDA ◽

Tadaaki NAKASHIMA ◽

Seiko ODA ◽

Tomomi NAKAMURA ◽

...

Keyword(s):

Systemic Lupus Erythematosus ◽

Case Report ◽

Lupus Erythematosus ◽

Medium Chain Triglyceride ◽

Systemic Lupus ◽

Protein Losing Enteropathy ◽

Medium Chain ◽

Medium Chain Triglyceride Diet

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Rickets and a medium chain triglyceride diet

Journal of Pediatric Surgery ◽

10.1016/0022-3468(73)90119-x ◽

1973 ◽

Vol 8 (3) ◽

pp. 439-440 ◽

Cited By ~ 2

Author(s):

James P. Keating ◽

Donald B. Strominger ◽

John Poulos

Keyword(s):

Medium Chain Triglyceride ◽

Medium Chain ◽

Medium Chain Triglyceride Diet

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Acute Iodine Toxicity from a Suspected Oral Methamphetamine Ingestion

Clinical Medicine Insights Case Reports ◽

10.4137/ccrep.s20086 ◽

2014 ◽

Vol 7 ◽

pp. CCRep.S20086 ◽

Cited By ~ 3

Author(s):

Marilyn N. Bulloch

Keyword(s):

Case Report ◽

Gastrointestinal Symptoms ◽

Liver Function Tests ◽

Oral Ingestion ◽

Methamphetamine Abuse ◽

Normal Limits ◽

Naturally Occurring ◽

History Of ◽

Systemic Symptoms ◽

Iodine Toxicity

Background Iodine is a naturally occurring element commercially available alone or in a multitude of products. Iodine crystals and iodine tincture are used in the production of methamphetamine. Although rarely fatal, iodine toxicity from oral ingestion can produce distressing gastrointestinal symptoms and systemic symptoms, such as hypotension and tachycardia, from subsequent hypovolemia. Objective The objective of this case report is to describe a case of iodine toxicity from suspected oral methamphetamine ingestion. Case Report A male in his early 20′s presented with gastrointestinal symptoms, chills, fever, tachycardia, and tachypnea after orally ingesting a substance suspected to be methamphetamine. The patient had elevated levels of serum creatinine, liver function tests, and bands on arrival, which returned to within normal limits by day 4 of admission. Based on the patient's narrow anion gap, halogen levels were ordered on day 3 and indicated iodine toxicity. This is thought to be the first documented case of iodine toxicity secondary to suspected oral methamphetamine abuse. Conclusion Considering that the incidence of methamphetamine abuse is expected to continue to rise, clinicians should be aware of potential iodine toxicity in a patient with a history of methamphetamine abuse.

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Intestinal lymphangiectasia: case report

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20194139 ◽

2019 ◽

Vol 6 (5) ◽

pp. 1678

Author(s):

Reham Mohmmad Aljohnei ◽

Hawazen Yousef Abdullah Alani

Keyword(s):

Case Report ◽

Rare Disease ◽

Present Report ◽

Abdominal Distention ◽

Intestinal Lymphangiectasia ◽

Peripheral Edema ◽

Long Duration ◽

White Spots ◽

Intestinal Lymphatics ◽

History Of

Primary intestinal lymphangiectasia (PIL) was first described by Waldmann et al, in 1961. PIL is a rare disease with several hundred reported cases. It is rarely reported in adults because it is presumably a congenital disorder and when present in adults it typically produces a long duration of manifestation such as diarrhea, abdominal distention from ascites, and peripheral edema. This disorder is characterized by markedly dilated intestinal lymphatics, hypoproteinemia, generalized edema, lymphocytopenia hypogammaglobinemia, and immunologic anomalies. The loss of protein into the from dilated intestinal lymphatics leads to the development of hypoproteinemia in these patients and its demonstration is important in the diagnosis of intestinal lymphangiectasia. The disease can be secondary to congenital, secondary or idiopathic defects in the formation of the lymphatic ducts. In the present report, we describe a case of 15 years old female presented to our hospital with history of generalized edema, bilateral hand spasm, and diarrhea. Endoscopy of the patient revealed White spots (dilated lacteals), white nodules, and submucosal elevations were observed. Changes suggestive of the disease includes White villi and/or spots (dilated lacteals), white nodules, and submucosal elevations are observed. Xanthomata’s plaques are often visualized, there are no specific treatments for patients with PIL. treatment of patients with primary intestinal lymphangiectasia involves control of symptoms with the use of dietary, pharmaceutical, and behavioral modifications.

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The fatal cholera like diarrhoea in coronavirus disease 2019(COVID-19)- a rare case report in toddler

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl1.4531 ◽

2020 ◽

Vol 11 (SPL1) ◽

pp. 1894-1897

Author(s):

Varsha Gajbhiye ◽

Shubhangi Patil (Ganvir) ◽

Sarika Gaikwad

Keyword(s):

Case Report ◽

Rare Case ◽

Digestive System ◽

Gastrointestinal Symptoms ◽

Female Child ◽

Multiple Organ ◽

Mild Case ◽

Severe Dehydration ◽

Rare Case Report ◽

History Of

A 14-month female child came with complain of cholera like watery loose stool 10-12 times and vomiting 6-7 times, 24 hrs before admission. She was in severe dehydration, hypotension, unconscious with no recorded fever during her stay in hospital and no history of contact with COVID-19. Patient was COVID-19 positive Dehydration and hypotension was corrected, metabolic acidosis continued and eventually patient succumb due to multiple organ failure. This case report should arouse us to suspect COVID infection in every acute Gastroenteritis child who may not have any common symptoms as seen in COVID patient, also who have no history of significant contact with COVID positive patient in family. Some people with COVID-19 develop gastrointestinal symptoms either alone or with respiratory symptoms. Recently, researchers at Stanford University found that a third of patients they studied with a mild case of COVID-19 had symptoms affecting the digestive system. Another recent study Trusted Source published by researchers in Beijing found that anywhere from 3 to 79 percent of people with COVID-19 develop gastrointestinal symptoms.

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