scholarly journals Uncommon cause of cardiac tamponade in a young man

2021 ◽  
Vol 14 (1) ◽  
pp. e239573
Author(s):  
Ananthu Narayan ◽  
Vineeta Ojha ◽  
Sudheer Arava ◽  
Animesh Ray

We report a rare case of cardiac angiosarcoma in a young boy who presented with cardiac tamponade. His initial symptoms were non-specific. He was initially being managed in the line of fungal infection, with a possibility of malignancy. Cardiac imaging was also not conclusive and he worsened on antibiotics and antifungals and succumbed to the illness. After his death tissue biopsy from heart and lung was done and histopathological examination revealed the diagnosis of metastatic angiosarcoma. The case highlights the importance of considering the diagnosis of cardiac angiosarcoma in the patients presenting with haemorrhagic pericardial effusion and non-specific symptoms.

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Roshanak Habibi ◽  
Negar Faramarzi ◽  
Alvaro J. Altamirano ◽  
Shahriar Dadkhah

Primary malignancies of the heart are so rare that most of the available data come from case reports or large single-center-based studies, with the overall incidence of 0.02% in the United States. Diagnosis in case of an isolated pericardial effusion as presentation is challenging, and determining that an angiosarcoma is even more challenging. Here, we presented a rare case of pericardial angiosarcoma which presented to us with tamponade. The patient eventually was diagnosed through pericardiectomy. A multimodality approach was attempted to treat the cancer. The clinical details of such a unique disease entity inspired us to present it as a case report.


Author(s):  
Elena Falchetti ◽  
Matteo Francioni ◽  
Maria Matassini ◽  
Stefano Menzo ◽  
Laura Morbidoni ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Kosuke Saku ◽  
Keisuke Yamamoto ◽  
Hironori Inoue ◽  
Masahiro Ueno

Silicosis is an occupational lung disorder caused by inhalation of silica dust. It not only causes respiratory disorders but also affects other organs. We report an extremely rare case of silicosis complicated by pericarditis in an 83-year-old male. He had been working as a coal miner and was diagnosed with silicosis at the age of 63. Because he had experienced repeated pericardial effusions, he was referred for a surgical pericardial biopsy to elucidate the cause of his repeated pericardial effusion and to perform pericardial fenestration. Thoracoscopic surgery was performed. The pericardium was resected, and a drain was placed in the left thoracic cavity. Histopathological examination revealed the pericardial degeneration due to silicosis, suggesting that pericarditis and pericardial effusion are related to silicosis. The operation was successful, and he experienced no recurrence of pericardial effusion at the 7-month follow-up.


2000 ◽  
Vol 36 (2) ◽  
pp. 121-124 ◽  
Author(s):  
JA Kirsch ◽  
S Dhupa ◽  
KK Cornell

A 6.5-year-old, spayed female Siberian husky presented with signs of cardiac tamponade and weakness. Pleural, pericardial, and abdominal effusion were identified with radiographs and ultrasound. Pericardiocentesis relieved signs of tamponade, and the dog was clinically improved. Pericardial effusion recurred, and pericardiectomy was performed. Histopathological examination of excised tissues failed to reveal evidence of infectious or neoplastic disease. After pericardiectomy, clinically apparent thoracic effusion persisted. The dog was euthanized, and postmortem histopathological examination revealed emboli of metastatic carcinoma cells in the epicardium. The location of intrathoracic disease in this dog made antemortem diagnosis difficult, if not impossible.


Author(s):  
Allan Klein ◽  
Bernard Cosyns ◽  
Aldo L. Schenone

Pericardial effusion (Peff) is a commonly encountered findings in clinical practice. It is usually asymptomatic, but can present as a life-threatening condition when cardiac tamponade ensues. The use of multimodality cardiac imaging has emerged as a crucial tool in the early detection and characterization of Peff and cardiac tamponade allowing prompt and effective treatment. Transthoracic echocardiography (TTE) is first-line imaging technique in the evaluation for Peff and cardiac tamponade. They key echocardiographic findings supporting cardiac tamponade include the presence of (1) cardiac chambers collapse; (2) an exaggerated ventricular interdependence; and (3) plethoric inferior vena cava (IVC). Advance cardiac imaging including transoesophageal echocardiography, cardiac CT, and cardiac MRI are reserved for complex cases with high suspicion for focal effusion or tamponade when TTE is unrevealing. Medical treatment of underlying cause is recommended for effusion without haemodynamic compromise, while emergent drainage is warranted when in cardiac tamponade.


2021 ◽  
Vol 9 ◽  
pp. 2050313X2110360
Author(s):  
Lardinois Benjamin ◽  
Goeminne Jean-Charles ◽  
Miller Laurence ◽  
Randazzo Adrien ◽  
Laurent Terry ◽  
...  

Immune-related adverse events including cardiac toxicity are increasingly described in patients receiving immune checkpoint inhibitors. We described a malignant pericardial effusion complicated by a cardiac tamponade in an advanced non-small cell lung cancer patient who had received five infusions of atezolizumab, a PDL-1 monoclonal antibody, in combination with cabozantinib. The definitive diagnosis was quickly made by cytology examination showing typical cell abnormalities and high fluorescence cell information provided by the hematology analyzer. The administration of atezolizumab and cabozantinib was temporarily discontinued due to cardiogenic hepatic failure following cardiac tamponade. After the re-initiation of the treatment, pericardial effusion relapsed. In this patient, the analysis of the pericardial fluid led to the final diagnosis of pericardial tumor progression. This was afterwards confirmed by the finding of proliferating intrapericardial tissue by computed tomography scan and ultrasound. This report emphasizes the value of cytology analysis performed in a hematology laboratory as an accurate and immediate tool for malignancy detection in pericardial effusions.


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