scholarly journals A Patient Presenting with Cardiac Tamponade and the Challenges of Finding Its Cause: A Cardiac Angiosarcoma

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Roshanak Habibi ◽  
Negar Faramarzi ◽  
Alvaro J. Altamirano ◽  
Shahriar Dadkhah
Keyword(s):  
United States ◽  
Case Report ◽  
Pericardial Effusion ◽  
Rare Case ◽  
Case Reports ◽  
The United States ◽  
Disease Entity ◽  
Single Center ◽  
Cardiac Angiosarcoma ◽  
Multimodality Approach

Primary malignancies of the heart are so rare that most of the available data come from case reports or large single-center-based studies, with the overall incidence of 0.02% in the United States. Diagnosis in case of an isolated pericardial effusion as presentation is challenging, and determining that an angiosarcoma is even more challenging. Here, we presented a rare case of pericardial angiosarcoma which presented to us with tamponade. The patient eventually was diagnosed through pericardiectomy. A multimodality approach was attempted to treat the cancer. The clinical details of such a unique disease entity inspired us to present it as a case report.

scholarly journals Sugammadex-Associated Hypotension, Bradycardia, Asystole, and Death

2020 ◽  
Vol 2020 ◽  
pp. 1-2
Author(s):  
Kazim Mirza ◽  
Kathryn Landoski ◽  
Dilip Thakar ◽  
Jagtar Heir-Singh ◽  
Timothy Jackson ◽  
...  
Keyword(s):  
United States ◽  
Case Report ◽  
Drug Administration ◽  
Muscle Relaxant ◽  
Case Reports ◽  
The United States ◽  
Binding Agent ◽  
Reversal Agent ◽  
The Family ◽  
Gamma Cyclodextrin

On December 16, 2015, the Food and Drug Administration (FDA) in the United States approved sugammadex (Bridion, Merck and Co), a modified gamma-cyclodextrin, to be used as a reversal agent. It is a first and unique selective nondepolarizing steroidal muscle relaxant (NDSMR) binding agent with a great affinity for rocuronium and vecuronium. However, there have been several recently published case reports of bradycardia and asystole immediately after sugammadex administration for the reversal. This report presents a case of sugammadex administration followed by rapidly progressing bradycardia leading to asystole and subsequent death. The family has provided the written consent to share this case report.

Acute Inflammatory Reaction Following Removal of Hydrophilic Polyacrylamide Gel

2018 ◽  
Vol 35 (2) ◽  
pp. 59-63
Author(s):  
Victoria Karlinsky ◽  
Judson Boisvert
Keyword(s):  
United States ◽  
Case Report ◽  
Inflammatory Reaction ◽  
Case Reports ◽  
The United States ◽  
Polyacrylamide Gel ◽  
Permanent Filler ◽  
Management Of Complications ◽  
The World ◽  
Acute Reaction

Hydrophilic polyacrylamide gel (PAAG), although not approved for use in the United States, has been used throughout the world as a permanent filler for aesthetic applications since the 1980s. Numerous articles and case reports have been published highlighting complications arising from its use. In this case report, we present a 54-year-old woman who presented for surgical consultation, requesting removal of previously injected polyacrylamide gel with subsequent silicone implant breast augmentation who experienced an acute reaction following attempted removal of the gel. This report reviews the current use, complications, and management of complications in patient’s previously injected with PAAG.

Cryptosporidiosis Presenting as Acute Appendicitis: A Case Report

2005 ◽  
Vol 71 (6) ◽  
pp. 537-538 ◽  
Author(s):  
Kerri Buch ◽  
Scott Nguyen ◽  
Celia M. Divino ◽  
Kaare Weber ◽  
Raffaella A. Morotti
Keyword(s):  
United States ◽  
Case Report ◽  
Acute Appendicitis ◽  
Acute Infection ◽  
The United States ◽  
Gastrointestinal Illness ◽  
Disease Entity ◽  
The Third ◽  
Life Threatening ◽  
Cryptosporidial Infection

Although uncommon in the United States, cryptosporidiosis can be life-threatening in an immunosuppressed host. Rarely, an acute infection of this gastrointestinal illness can present as another disease entity. We present only the third reported case of cryptosporidial infection presenting as acute appendicitis in a 17-year-old HIV+ patient.

Linezolid Induced Skin Reactions in a Multi Drug Resistant Infective Endocarditis Patient: A Rare Case

2020 ◽  
Vol 15 (3) ◽  
pp. 222-226 ◽  
Author(s):  
Asha K. Rajan ◽  
Ananth Kashyap ◽  
Manik Chhabra ◽  
Muhammed Rashid
Keyword(s):  
Case Report ◽  
Infective Endocarditis ◽  
Rare Case ◽  
Case Reports ◽  
Multidrug Resistant ◽  
The Body ◽  
Prior History ◽  
Skin Reactions ◽  
Rare Case Report ◽  
Multiple Drugs

Rationale: Linezolid (LNZ) induced Cutaneous Adverse Drug Reactions (CADRs) have rare atypical presentation. Till date, there are very few published case reports on LNZ induced CADRs among the multidrug-resistant patients suffering from Infective Endocarditis (MDR IE). Here, we present a rare case report of LNZ induced CARs in a MDR IE patient. Case report: A 24-year-old female patient was admitted to the hospital with chief complaints of fever (101°C) associated with rigors, chills, and shortness of breath (grade IV) for the past 4 days. She was diagnosed with MDR IE, having a prior history of rheumatic heart disease. She was prescribed LNZ 600mg IV BD for MDR IE, against Staphylococcus coagulase-negative. The patient experienced flares of cutaneous reactions with multiple hyper-pigmented maculopapular lesions all over the body after one week of LNZ therapy. Upon causality assessment, she was found to be suffering from LNZ induced CADRs. LNZ dose was tapered gradually and discontinued. The patient was prescribed corticosteroids along with other supportive care. Her reactions completely subsided and infection got controlled following 1 month of therapy. Conclusion: Healthcare professionals should be vigilant for rare CADRs, while monitoring the patients on LNZ therapy especially in MDR patients as they are exposed to multiple drugs. Moreover, strengthened spontaneous reporting is required for better quantification.

scholarly journals Complications of drowning: A case report

2019 ◽  
Vol 59 (5) ◽  
pp. 284-8
Author(s):  
Felicia Anita Wijaya ◽  
I Gde Doddy Kurnia Indrawan
Keyword(s):  
United States ◽  
Case Report ◽  
Brain Damage ◽  
The United States ◽  
Accidental Death ◽  
Common Cause ◽  
Death By Drowning

Unintentional drowning is the sixth most common cause of accidental death, accounting for 4,086 deaths (1.4 per 100,000) in the United States in 2007.1 In children, drowning is the second leading cause of injury-related death, and those aged 1–3 years have the highest rate of drowning.2 More than 1,400 pediatric drownings were reported in the United States in 2008.3 Many drowning deaths are due to lack of supervision in the bathtub, unprotected access to a pool, or lack of swimming skills.3 For every death by drowning, six children are hospitalized for drowning, and up to 10% of survivors experience severe brain damage.2

scholarly journals 354. The Epidemiology and Clinical Features of Acanthamoeba Disease in the United States, 1956–2018

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S246-S246
Author(s):  
Kevin O’Laughlin ◽  
Jennifer R Cope ◽  
Zachary A Marsh
Keyword(s):  
United States ◽  
Case Reports ◽  
The United States ◽  
Severe Illness ◽  
People Living With Hiv ◽  
Cutaneous Lesions ◽  
Free Living ◽  
Organ Systems ◽  
Free Living Ameba ◽  
Soil And Water

Abstract Background Acanthamoeba is a free-living ameba found worldwide in soil and water that can cause severe illness. Transmission is thought to be through the skin, eyes, or lungs; Acanthamoeba can cause disseminated infection (Acanthamoeba disease) in addition to the more widely recognized Acanthamoeba keratitis. Infections however are rare, and only case reports or small case series have been published. We review Acanthamoeba disease cases from the Centers for Disease Control and Prevention (CDC) free-living ameba registry to characterize the disease in the United States. Methods CDC maintains a free-living ameba (FLA) registry of laboratory-confirmed Acanthamoeba cases (excluding keratitis) sourced from published case reports, CDC case report forms, and CDC laboratory results. SAS© version 9.4 software was used to calculate descriptive statistics and frequencies. Results We identified 163 cases of Acanthamoeba disease between 1956 and 2018. Of cases with documented outcome, 85% were fatal (105/124). Most (88%) cases were in patients who were immunocompromised (136/155): 66 people living with HIV (of whom 49 were classified as having AIDS); 33 recipients of organ transplantation; 30 people diagnosed with malignancy. The most common manifestation of disease was encephalitis (49%). Other clinical presentations included cutaneous lesions (20%) and rhinosinusitis (6%); 40 cases involved multiple organ systems. Median patient age was 42 years (range 0–83 years). Males accounted for 71% (114/160) of cases. California (29) and Texas (14) had the most case reports; 30 other states reported cases. The source of exposure was unknown in most cases (75%); soil and water were documented in 14 and 17 cases, respectively. Conclusion Acanthamoeba disease in the United States is primarily characterized by encephalitis and cutaneous lesions that affect predominately immunocompromised individuals. Acanthamoeba as a cause of encephalitis in immunocompromised patients should be considered by clinicians, which may lead to earlier diagnosis and treatment. Disclosures All Authors: No reported disclosures

scholarly journals Pericardial effusion and cardiac tamponade requiring pericardial window in an otherwise healthy 30-year-old patient with COVID-19: a case report

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Christina Walker ◽  
Vincent Peyko ◽  
Charles Farrell ◽  
Jeanine Awad-Spirtos ◽  
Matthew Adamo ◽  
...  
Keyword(s):  
Case Report ◽  
Pericardial Effusion ◽  
Cardiac Tamponade ◽  
Case Reports ◽  
Healthy Woman ◽  
Signs And Symptoms ◽  
Rare Presentation ◽  
Pericardial Window ◽  
Acute Pericarditis ◽  
Novel Coronavirus

Abstract Background This case report demonstrates pericardial effusion, acute pericarditis, and cardiac tamponade in an otherwise healthy woman who had a positive test result for coronavirus disease 2019. Few case reports have been documented on patients with this presentation, and it is important to share novel presentations of the disease as they are discovered. Case presentation A Caucasian patient with coronavirus disease 2019 returned to the emergency department of our hospital 2 days after her initial visit with worsening chest pain and shortness of breath. Imaging revealed new pericardial effusion since the previous visit. The patient became hypotensive, was taken for pericardial window for cardiac tamponade with a drain placed, and was treated for acute pericarditis. Conclusion Much is still unknown about the implications of coronavirus disease 2019. With the novel coronavirus disease 2019 pandemic, research is still in process, and we are slowly learning about new signs and symptoms of the disease. This case report documents a lesser-known presentation of a patient with coronavirus disease 2019 and will help to further understanding of a rare presentation.

scholarly journals Autochthonous Furuncular Myiasis in the United States: Case Report and Literature Review

2003 ◽  
Vol 36 (7) ◽  
pp. e73-e80 ◽  
Author(s):  
Nasia Safdar ◽  
Daniel K. Young ◽  
David Andes
Keyword(s):  
United States ◽  
Case Report ◽  
Literature Review ◽  
The United States ◽  
Furuncular Myiasis

Aflatoxin B1: Its Role in the Etiology of Reye's Syndrome

PEDIATRICS ◽  
1979 ◽  
Vol 64 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Nell J. Ryan ◽  
Gwendolyn R. Hogan ◽  
A. Wallace Hayes ◽  
Peter D. Unger ◽  
Mohamed V. Siraj
Keyword(s):  
United States ◽  
Acute Phase ◽  
Aflatoxin B1 ◽  
Case Reports ◽  
The United States ◽  
Reye's Syndrome ◽  
Autopsy Specimens

Seven cases of Reye's syndrome in which aflatoxin B1 was isolated from the blood or liver or both are presented. In two cases aflatoxin B1 was found in the blood during the acute phase of the disease; a finding not previously reported. In six cases aflatoxin B1 was recovered from autopsy specimens of liver. A number of case reports linking aflatoxin B1 to Reye's syndrome have appeared in the literature but until now only one case has been reported from the United States. Aflatoxin B1 and its possible role in the etiology of Reye's syndrome is discussed. It is concluded that Reye's syndrome is the result of multiple interrelated factors.

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