Stratus OCT image analysis with spectral-domain OCT (Topcon 3D OCT Viewer)

Aims: To evaluate the optic coherence tomographic (OCT) features in acute central serous chorioretinopathy (ACSC) with time-domain or spectral-domain OCT at Dokuz Eylul University, Department of Ophthalmology, Izmir, Turkey.Subjects and Methods: Clinical data from the Department of Ophthalmology (of Dokuz Eylul University) including fluorescein angiography (FA) and OCT findings of 39 eyes of 34 patients with ACSC were retrospectively analyzed. Eleven eyes (Ntd =11) were examined with time-domain (Stratus OCT 3, Version 4.0) and 28 eyes (Nsd =28) with spectral-domain OCT (Heidelberg HRA2 Spectralis).Results: Of the sample of 34, twenty-four patients (70.6%) were men and 10 women (29.4%). FA demonstrated smokestack type hyperfluorescence in five eyes (12.8%), a round ink blot type hyperfluorescence in 32 eyes (82.1%) and diffuse leak-age in two (5.1%) eyes. Twenty-five eyes (64.1%) had only one leakage site, five eyes (12.8%) hadtwo leakage sites and nine eyes (23.1%) had three or more leakage sites. Detachment of the neurosensory retina was detected in 37 eyes (94.9%, 11 eyes with Stratus OCT and 26 eyes with Spectral OCT). Pigment epithelial detachment (PED) was detected in nine eyes (23.1%, one eye with Stratus OCT and eight eyes with Spectral OCT). Protrusion of the RPE layer was detected in 10 eyes (25.6%, all eyes with Spectral OCT). Both fibrinous exudates and bridging between the neurosensory retina and PED was detected with Spectral OCT in four eyes (10.2%). Retinal dipping was detected with Spectral OCT in two eyes (5.1%).Conclusion: Spectral-domain OCT seems to yield more information and depicts RPE layer protrusion, fibrinous exudates and bridging better when compared to conventional time-domain OCT. (S Afr Optom 2012 71(4) 166-170)

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Spectral Domain OCT Documented Resolution of Pseudophakic Cystoid Macular Edema after Intravitreal Triamcinolone

Ophthalmology and Eye Diseases ◽

10.4137/oed.s3671 ◽

2010 ◽

Vol 2 ◽

pp. OED.S3671

Author(s):

Ravi K Murthy ◽

Kakarla V. Chalam

Keyword(s):

Macular Edema ◽

Cystoid Macular Edema ◽

Spectral Domain ◽

Vascular Endothelial ◽

Intravitreal Triamcinolone ◽

Cross Sectional ◽

Spectral Domain Oct ◽

Endothelial Growth Factor ◽

Stratus Oct ◽

Sd Oct

Cystoid macular edema (CME) is an important cause of visual loss after cataract surgery. Treatment is usually with topical anti-inflammatory agents, with anti-vascular endothelial growth factor agents and steroids used intravitreally in resistant cases. Even though time-domain Stratus OCT can quantify the macular thickness, it cannot prognosticate visual outcomes due to the poor resolution of images, especially the outer segment-inner segment junction. Spectral-domain OCT (SD-OCT) by its ability to acquire large number of images in a short span of time provides high resolution cross-sectional images of the retina, which not only highlights the underlying pathological changes, but in addition can prognosticate visual recovery. We describe pre and post SD-OCT features of a case of refractory CME who was treated with intravitreal triamcinolone actetonide.

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Comparison between time-domain and spectral-domain OCT in the detection of retinal nerve fiber layer defects in glaucoma patients

International Eye Research ◽

10.18240/ier.2020.02.05 ◽

2020 ◽

Vol 1 (2) ◽

pp. 89-94

Author(s):

Jae Keun Chung ◽

Keyword(s):

Nerve Fiber ◽

Retinal Nerve Fiber Layer ◽

Time Domain ◽

Spectral Domain ◽

Fiber Layer ◽

Nerve Fiber Layer ◽

Spectral Domain Oct ◽

Spectralis Oct ◽

Stratus Oct ◽

Retinal Nerve Fiber

AIM: To compare, using the instruments’ built-in normative databases, the sensitivities of time-domain optical coherence tomography (Stratus OCT) and spectral-domain OCT (Spectralis OCT) in the detection of retinal nerve fiber layer (RNFL) defects in patients with glaucoma. METHODS: Fifty-two eyes of 35 patients with open angle glaucoma were included. A total of 69 hemiretinas with photographically identified RFNL defects were analyzed using the fast RNFL scan of Stratus OCT and the circle scan in Spectralis OCT. The OCT parameters were evaluated at 5% and 1% abnormality levels using the instruments’ built-in normative databases. The diagnostic sensitivity of each parameter was compared between the two devices. RESULTS: The Spectralis OCT detected RNFL defects within each quadrant more frequently than the Stratus OCT at both the 5% (79.7% vs 63.8%, P=0.01) and 1% (56.5% vs 40.6%, P=0.01) abnormality levels. At the 1% abnormality level, the sensitivity was significantly higher in the standard sector of Spectralis OCT than in the clock-hour sector of the Stratus OCT (68.1% vs 39.1%, P<0.01).

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Photoreceptor dysfunction in early and intermediate age-related macular degeneration assessed with mfERG and spectral domain OCT

Documenta Ophthalmologica ◽

10.1007/s10633-016-9523-4 ◽

2016 ◽

Vol 132 (1) ◽

pp. 17-26 ◽

Cited By ~ 8

Author(s):

Shasha Yang ◽

Chengguo Zuo ◽

Hui Xiao ◽

Lan Mi ◽

Guangwei Luo ◽

...

Keyword(s):

Macular Degeneration ◽

Age Related Macular Degeneration ◽

Spectral Domain ◽

Spectral Domain Oct ◽

Age Related

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Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography

Journal of Ophthalmology ◽

10.1155/2016/6956717 ◽

2016 ◽

Vol 2016 ◽

pp. 1-9 ◽

Cited By ~ 48

Author(s):

Pierre-Maxime Lévêque ◽

Pierre Zéboulon ◽

Emmanuelle Brasnu ◽

Christophe Baudouin ◽

Antoine Labbé

Keyword(s):

Visual Field ◽

Univariate Analysis ◽

Normal Subjects ◽

Vessel Density ◽

Spectral Domain ◽

Control Group ◽

Mean Deviation ◽

Ganglion Cell Complex ◽

Fiber Layer ◽

Spectral Domain Oct

Purpose. To detect changes in optic nerve head (ONH) vascularization in glaucoma patients using spectral-domain OCT angiography (OCT-A).Material and Method. Fifty glaucoma patients and 30 normal subjects were evaluated with OCT-A (AngioVue®, Optovue). The total ONH vessel density and temporal disc vessel density were measured. Clinical data, visual field (VF) parameters, and spectral-domain OCT evaluation (RNFL: retinal nerve fiber layer thickness, GCC: ganglion cell complex thickness, and rim area) were recorded for glaucoma patients. Correlations among total and temporal ONH vessel density and structural and VF parameters were analyzed.Results. In the glaucoma group, total and temporal ONH vessel density were reduced by 24.7% (0.412 versus 0.547;p<0.0001) and 22.88% (0.364 versus 0.472;p=0.001), respectively, as compared with the control group. Univariate analysis showed significant correlation between rim area (mm2) and temporal ONH vessel density (r=0.623;p<0.0001) and total ONH vessel density (r=0.609;p<0.0001). Significant correlations were found between temporal and total ONH vessel density and RNFL, GCC, VF mean deviation, and visual field index.Conclusion. In glaucoma patients OCT-A might detect reduced ONH blood vessel density that is associated with structural and functional glaucomatous damage. OCT-A might become a useful tool for the evaluation of ONH microcirculation changes in glaucoma.

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