scholarly journals Trephine biopsy for diffuse lung lesions.

BMJ ◽  
1967 ◽  
Vol 3 (5556) ◽  
pp. 30-32 ◽  
Author(s):  
S. J. Steel ◽  
D. P. Winstanley
2019 ◽  
Vol 61 (10) ◽  
pp. 1062-1063
Author(s):  
Hiroyuki Yoshizawa ◽  
Keiji Nogami ◽  
Hiroaki Yaoi ◽  
Midori Shima

1929 ◽  
Vol 49 (4) ◽  
pp. 695-700 ◽  
Author(s):  
Julia T. Parker

The necrotizing and lung-toxic principles present in certain anaerobically prepared autolysates of Pneumococcus Types I and II are similar in respect to extreme sensitiveness to heat and to oxidation, and to their ability to be neutralized by the same anti-autolysate serums. These two poisons differ, however, in their ability to be adsorbed or inactivated by red cells; the lung-toxic principle being adsorbed or inactivated by such procedure while the necrotizing principle is not. Since pneumococcus hemotoxin is present in the anaerobic autolysates and is also adsorbed by red cells, it seemed possible that it was this substance in the autolysates which caused the diffuse lung lesions and death of guinea pigs. However, it was found that the intratracheal injection of pneumococcus hemotoxin prepared by the method of Avery and Neill only occasionally produced the characteristic reaction caused by the intratracheal injection of the anaerobic autolysates.


2021 ◽  
Vol 5 (6) ◽  
Author(s):  
Qin-Hua Zhao ◽  
Wen-Hui Wu ◽  
Li-Jun Fu ◽  
Lan Wang

Abstract Background Cobalamin C (cbl-C) defect is an inherited autosomal recessive disorder that commonly affects the central nervous system of infants. Severe pulmonary hypertension (PH) and diffuse lung lesions are unusual clinical manifestations, especially among adults. Case summary A 25-year-old man with hypoxaemia, diffuse lung lesions, and PH, suddenly developed nausea, vomiting, headache, and worsening of dyspnoea. Metabolic screening showed elevated serum levels of methylmalonic acid and homocysteine, and genetic testing revealed MMACHC gene mutations. He was eventually diagnosed with severe PH secondary to cbl-C defect and was successfully managed with vitamin B12, betaine, L-carnitine, folate, as well as ambrisentan and sildenafil. Discussion cbl-C is a rare cause of PH and can present with severe PH and diffuse lung lesions in adults. Given that the condition is treatable, a careful metabolic screening should be considered when a diagnosis of PH is made.


1992 ◽  
Vol 28 (6) ◽  
pp. 897 ◽  
Author(s):  
Young Rahn Lee ◽  
Myung Gyu Kim ◽  
Eun Young Kang ◽  
Won Hyuck Suh

2019 ◽  
Vol 1 (9) ◽  
pp. 53-57
Author(s):  
T. N. Gavva ◽  
L. V. Kuzmenkova ◽  
Yu. N. Fedulaev ◽  
T. V. Pinchuk ◽  
D. D. Kaminer ◽  
...  

A case of lung damage in systemic lupus erythematosus (SLE) in a 33-year-old woman is described. This case is of clinical interest due to the complexity of diagnosis due to the fact that SLE is a disease with diverse clinical manifestations involving many organs and systems, which often makes it difficult to timely recognize the onset of the disease. SLE still remains a challenge and requires special attention to the patient s history, clinical and laboratory parameters of the patient, as well as specific immunological examinations.


2006 ◽  
Vol 228 (9) ◽  
pp. 1396-1396
Author(s):  
Joseph A. Daniel ◽  
Jeff E. Held ◽  
Denise G. Brake ◽  
Duane M. Wulf ◽  
William B. Epperson
Keyword(s):  

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